Results 121 to 130 of about 82,632 (214)
The Sindbis virus (SINV) nucleocapsid protein (NCP) is a 264 amino acid protein that is involved in a variety of functions in the virus life cycle. In addition to its role as a viral structural protein and an RNA-binding protein, the NCP is also a serine
Little, Carla Norrene
core +1 more source
Upon JEV infection, ZNF33B recruits METTL14 to stabilize the METTL3‐METTL14 m6A methyltransferase complex, leading to increased m6A modification of host transcripts, including Trim25 mRNA. ZNF33B selectively binds m6A‐modified sites on Trim25 mRNA and accelerates its decay, resulting in reduced TRIM25 protein abundance.
Jian Du +9 more
wiley +1 more source
The Significance of cGAS‐STING Signaling in Response to Oncogenic Viruses
ABSTRACT The cyclic GMP‐AMP synthase (cGAS)‐stimulator of interferon genes (STING) signaling pathway, as a key DNA sensor, plays a significant role in the regulation of innate immune responses. This pathway can be activated by sensing abnormal DNA, and is of great significance for resisting the invasion of pathogenic microorganisms and maintaining ...
Limei Guo +4 more
wiley +1 more source
Purification of nucleocapsid of tospoviruses from Chenopodium quinoa leaves v1
Purification of nucleocapsid of tospoviruses from Chenopodium quinoa leaves
Tsung-Chi Chen
core +1 more source
Whether viral lipids can directly interact with pattern recognition receptors to modulate antiviral immune responses remains unclear. We show that Mincle‐dependent recognition of HCMV viral particles induces proinflammatory cytokine production in primary human macrophages.
Vladimir Bokun +6 more
wiley +1 more source
ABSTRACT Background and Aims Long COVID, also known as post‐acute sequelae of SARS‐CoV‐2 infection (PASC), is a multisystem condition characterized by persistent symptoms that continue beyond the acute phase of infection. Growing evidence indicates that sustained immune dysregulation involving cytokine‐mediated inflammation, complement activation ...
Emmanuel Ifeanyi Obeagu
wiley +1 more source
Serodiagnosis of avian infectious bronchitis virus using recombinant nucleocapsid protein
Due to the character of the original source materials and the nature of batch digitization, quality control issues may be present in this document. Please report any quality issues you encounter to digital@library.tamu.edu, referencing the URI of the ...
Ndifuna, Abdul-El-Nuru
core +1 more source
This study generates a comprehensive Ebola virus (EBOV)‐human protein–protein interactome, comprising 1728 core high‐confidence interactions. Further interactome analysis revealed the potential association of EBOV glycoprotein (GP) with the host factor TM9SF2. Subsequent mechanistic investigations confirmed that TM9SF2 functions as an attachment factor
Limin Shang +16 more
wiley +1 more source
ANDV nucleocapsid protein inhibits caspase 3-activity.
Analysis of possible interactions between ANDV nucleocapsid protein and caspase 3. (A) Western blot analyses showing a cleaved fragment of the ANDV nucleocapsid protein (ANDV-N) after incubation with recombinant caspase 3 in the presence or absence of ...
Karin B. Sundström (337165) +7 more
core +1 more source
Protein modification by the ubiquitin-like protein ISG15 (ISGylation) plays a crucial role in the immunological defense against viral infection. During severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, innate immune signaling ...
Wonjin Bang +10 more
doaj +1 more source

