Results 121 to 130 of about 84,247 (263)

Mouse Hepatitis Coronavirus Nucleocapsid Phosphorylation [PDF]

, 2006
The coronavirus nucleocapsid (N) is a multifunctional phosphoprotein that encapsidates the genomic RNA into a helical nucleocapsid within the mature virion. The protein also plays roles in viral RNA transcription and/or replication and possibly viral mRNA translation.
White, Tiana C., Hogue, Brenda G.
openaire   +2 more sources

Construction optimization and functional applications of fluorescent nanodiamonds

Responsive Materials, EarlyView.
This review summarizes synthesis, surface modification and optical properties of fluorescent nanodiamonds. Their advances in quantum sensing, single‐photon emission and biomedicine are discussed, and existing challenges and future directions are presented.
Yunpeng Yang, Sen Zhang, Chao Chen, Wensi Yang, Zuanquan Chen, Rui Fan, Linlin Liu, Benjian Liu, Kang Liu, Zhibo Zhang, Bing Dai, Jiaqi Zhu   +11 more
wiley   +1 more source

Bovine Herpesvirus Type 4 (BoHV-4) Vector Delivering Nucleocapsid Protein of Crimean-Congo Hemorrhagic Fever Virus Induces Comparable Protective Immunity against Lethal Challenge in IFNα/β/γR−/− Mice Models

Viruses, 2019
Crimean-Congo hemorrhagic fever virus (CCHFV) is the causative agent of a tick-borne infection with a significant mortality rate of up to 40% in endemic areas, with evidence of geographical expansion.
Touraj Aligholipour Farzani, Katalin Földes, Alireza Hanifehnezhad, Burcu Yener Ilce, Seval Bilge Dagalp, Neda Amirzadeh Khiabani, Koray Ergünay, Feray Alkan, Taner Karaoglu, Hurrem Bodur, Aykut Ozkul   +10 more
doaj   +1 more source

Rapid and Efficient Affinity Isolation of Engineered Extracellular Vesicles Encapsulating Functional Proteins via Internal Twin‐Strep Tetraspanin Tagging

Small, EarlyView.
Structure‐guided internal twin‐Strep tagging of the tetraspanins CD63 or CD9 enables rapid and efficient antibody‐free affinity isolation of engineered extracellular vesicles (EVs) using Strep technology while allowing luminal protein loading. The approach removes over 96% of contaminants, separates tagged EVs from coexisting viral particles, and ...
Minh‐Tu Pham, Jona Benjamin Krohn, Janis Meyer, Christian Ritter, Martin Schneider, Dominic Helm, Dario Frey, Kleopatra Rapti, Uta Haselmann‐Weiss, Elif Toprak, Viet Loan Dao Thi, Florian Leuschner, Dirk Grimm, Karl Rohr, Ralf Bartenschlager   +14 more
wiley   +1 more source

Structural basis for Ebola virus nucleocapsid assembly and function regulated by VP24 [PDF]

エボラウイルス粒子の「中核」構造を解明 --VP24タンパク質の異なる結合様式がウイルス増殖制御のカギに-- . 京都大学プレスリリース. 2025-03-11.The Ebola virus, a member of the Filoviridae family, causes severe hemorrhagic fever in humans.
Houri, Kazuya, Sugita, Y., Ng, Yen Ni, Houri, K., Fujita-Fujiharu, Y., Muramoto, Yukiko, Fujita-Fujiharu, Yoko, Nakano, Masahiro, Takamatsu, Y., Muramoto, Y., Noda, Takeshi, Nakano, M., Noda, T., Sugita, Yukihiko, Hu, Shangfan, Hirabayashi, Ai, Takamatsu, Yuki, Ng, Y., Hu, S., Hirabayashi, A.   +19 more
core   +1 more source

Strategies for enhancing sensitivity in lateral flow assays

VIEW, EarlyView.
Lateral flow assays (LFAs) are essential for cost‐effective, rapid point‐of‐care diagnostics. However, conventional colourimetric LFAs often lack the sensitivity required for low‐abundance biomarkers. This review evaluates six enhancement strategies: flow modulation, sample preconcentration, advanced reporters, chemical signal amplification, structural
Aylar Eslami Saed, Jacopo Giaretta, Syamak Farajikhah, Fariba Dehghani   +3 more
wiley   +1 more source

Ebola virus nucleocapsid-like particles demonstrate consistent assembly, but a wide range of helical condensation [PDF]

, 2017
The overall goal of this thesis was to determine whether envelope-free Ebola virus (EBOV) nucleocapsids could be isolated. We identified novel structures from EBOV infected cells that we have termed “proto-nucleocapsids”.
Rabb, Melissa
core  

Autographa californica multiple nucleopolyhedrovirus 38K is a novel nucleocapsid protein that interacts with VP1054, VP39, VP80, and itself

, 2008
It has been shown that the Autographa californica multiple nucleopolyhedrovirus (AcMNPV) 38K (ac98) is required for nucleocapsid assembly. However, the exact role of 38K in nucleocapsid assembly remains unknown.
Pang, Yi, Liu, Chao, Liang, Chun, Kan, Junsuo, Yang, Kai, Wu, Wenbi, Liang, Hanquan, Yuan, Meijin   +7 more
core   +1 more source

Nucleocapsid Structure of Negative Strand RNA Virus

, 2020
Negative strand RNA viruses (NSVs) include many important human pathogens, such as influenza virus, Ebola virus, and rabies virus. One of the unique characteristics that NSVs share is the assembly of the nucleocapsid and its role in viral RNA synthesis ...
Ming Luo, James Ross Terrell, Shelby Ashlyn Mcmanus   +2 more
core   +1 more source

Co-Delivery Effect of CD24 on the Immunogenicity and Lethal Challenge Protection of a DNA Vector Expressing Nucleocapsid Protein of Crimean Congo Hemorrhagic Fever Virus

Viruses, 2019
Crimean Congo hemorrhagic fever virus (CCHFV) is the causative agent of a globally-spread tick-borne zoonotic infection, with an eminent risk of fatal human disease.
Touraj Aligholipour Farzani, Alireza Hanifehnezhad, Katalin Földes, Koray Ergünay, Erkan Yilmaz, Hiba Hashim Mohamed Ali, Aykut Ozkul   +6 more
doaj   +1 more source