Results 141 to 150 of about 105,644 (246)

Stimulus-responsive assembly of nonviral nucleocapsids

Nature Communications
AbstractControlled assembly of a protein shell around a viral genome is a key step in the life cycle of many viruses. Here we report a strategy for regulating the co-assembly of nonviral proteins and nucleic acids into highly ordered nucleocapsids in vitro.
Mao Hori, Angela Steinauer, Stephan Tetter, Jamiro Hälg, Eva-Maria Manz, Donald Hilvert   +5 more
openaire   +4 more sources

SARS‐CoV‐2 Variants and Immune Evasion: Mapping the Future of Vaccine Design

Reviews in Medical Virology, Volume 36, Issue 3, May 2026.
ABSTRACT The evolutionary trajectory of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS‐CoV‐2) has progressed through several distinct phases since its zoonotic emergence, transitioning from initial human adaptation to an era of rapid antigenic drift and complex immune evasion. As of early 2026, the global landscape is dominated by highly evolved
Fatih Uzer, Fulya Erendor, Salih Sanlioglu   +2 more
wiley   +1 more source

Identification of individuals with gonorrhoea within sexual networks: a population-based study.

, 2006
BACKGROUND: Molecular typing of Neisseria gonorrhoeae and contact tracing provide a combined approach for analysis of sexual networks in metropolitan areas, although there are some difficulties in application.
Bishop, Cynthia J, Choudhury, Bhudipa, Fenton, Kevin A, Ghani, Azra C, Ison, Catherine A, Risley, Claire L, Spratt, Brian G, Ward, Helen   +7 more
core   +1 more source

Evaluation of Selected Brain Damage Biomarkers in the Determination of Brain Damage in Dogs With Neurological Distemper

Veterinary Medicine and Science, Volume 12, Issue 3, May 2026.
In this study, a significant increase in serum NSE, GFAP, CK‐B, IgM and IgM concentrations was determined in dogs with nervous distemper. It was shown that NSE, GFAP and CK‐B biomarkers have a useful and reliable diagnostic value in determining brain damage in dogs with nervous distemper .
Muhammed Mustafa Kapar, Mahmut Ok, Oğuzhan Avcı   +2 more
wiley   +1 more source

SARS‐CoV‐2 nucleocapsid protein variants have differential RNA chaperone activity

The FEBS Journal, Volume 293, Issue 9, Page 2579-2598, May 2026.
The SARS‐CoV‐2 nucleocapsid (N) protein is not only the specific viral RNA packaging protein, but also acts as an RNA chaperone, facilitating RNA folding. We show that it facilitates RNA annealing through its RBD–IDR2–CTD region, identifying it as a functional RNA chaperone.
Sabrina Babl, Julia M. Seidel, Fabian Kugler, Elisabeth Silberhorn, Anna Ludwig, Jonas Abel, Sophia Winklbauer, Niklas Schaub, Silvia Materna‐Reichelt, Kamran Honarnejad, Nataša Stojanović Gužvić, Gernot Längst   +11 more
wiley   +1 more source

Tomato Spotted Wilt Virus Reprogrammes Host Glycolysis to Facilitate Proliferation by a Phase‐Separated Co‐Aggregate of Nucleocapsid Protein and Phosphoglycerate Kinase

Plant Biotechnology Journal, Volume 24, Issue 5, Page 2826-2842, May 2026.
ABSTRACT Efficient viral proliferation within the host is a critical step in pathogenicity and requires adenosine triphosphate (ATP). The replication, movement and immune evasion of many plant viruses within their hosts are associated with phase separation (PS)‐derived aggregates formed by viral components.
Guangcheng Zu, Zhifu Xing, Jiao Li, Tangbing Yang, Huan Wu, Qiangsheng Ge, Yanju Wang, Baoan Song, Runjiang Song   +8 more
wiley   +1 more source

SARS-CoV-2 structural proteins affect the expression of IL-8 and TNF-α cytokines and APOBEC genes in human lung A549 and liver Huh-7 cells

Acta Pharmaceutica
The apolipoprotein B mRNA editing catalytic polypeptide-like (APOBEC) proteins belong to a family of cytidine deami nases responsible for DNA and RNA sequence editing, playing pivotal roles in a wide range of biological processes, including immune ...
Marušič Martina Bergant, Costa Margarida, Turk Špela, Lovšin Nika   +3 more
doaj   +1 more source

Nanoassemblies of an Artificial Ferric Enterobactin Analog for Biosensing Enterobacteriaceae

ChemElectroChem, Volume 13, Issue 8, 15 April 2026.
Nanoassemblies of an artificial trisamine‐based Ferric Enterobactin, analogs to natural enterobactin and ferric enterobactin, is reported as molecular recognition receptors for real‐time biosensing. The electrochemical sensors, made from the nanoassemblies of its iron(III)complex, exhibit rapid anodic peak current changes upon exposure to live cells of
Selina Laws, Ndepana Andrew, Robson L. Grosso, Matthew Carnaghi, Hemali Rathnayake   +4 more
wiley   +1 more source

Topographical mapping of epitopes on the glycoproteins of murine hepatitis virus-4 (strain JHM): correlation with biological activities. [PDF]

, 1984
Monoclonal hybridoma antibodies (MAb) of defined polypeptide specificity and biological activity were used in a competition binding assay to identify antibody binding sites (epitopes) on the glycoproteins of murine hepatitis virus-4 strain JHM (MHV-4 ...
Buchmeier, MJ, Knobler, RL, Salmi, AA, Talbot, PJ   +3 more
core  

Detection of eight different tospovirus species by a monoclonal antibody against the common epitope of NSs protein [PDF]

Rabbit antisera against the nucleocapsid protein (NP) have been commonly used for detection of tospoviruses and classification into serogroups or serotypes. Mouse monoclonal antibodies (MAbs) with high specificity to the NPs have also been widely used to
Chen, T.C., Kang, Y.C., Kormelink, R.J.M., Li, J.T., Lu, Y.Y., Yeh, S.D., Yeh, Y.C.   +6 more
core   +2 more sources