Results 101 to 110 of about 84,247 (263)
Journal of General Virology, 1993 The gene encoding the major nucleocapsid, N, protein of measles virus has been inserted into a baculovirus vector under the control of the polyhedrin promoter. Insect cells infected with this recombinant baculovirus synthesize high levels of measles N protein, up to 40% of total soluble cell protein.
A R, Fooks +5 more
openaire +2 more sources
Electron, EarlyView.Physics‐driven advances in optical nanobiosensors for rapid, miniaturized, and point‐of‐care diagnostics for next‐generation decentralized and personalized healthcare based on sensor intelligence. ABSTRACT Public health emergencies and the escalating burden of chronic diseases necessitate a paradigm shift from centralized laboratory testing to rapid ...
Vishal Chaudhary +5 more
wiley +1 more source
Structure-Function Relationships of the Nucleocapsid in Vesicular Stomatitis Virus
, 2018 Understanding the basic structure-function relationships that guide the biology of various pathogenic viruses is the cornerstone in the development of antiviral therapies.
Gumpper, Ryan
core +1 more source
Illuminating point‐of‐care diagnostics with aggregation‐induced emission biosensors
FlexMat, EarlyView.This review highlights the application of aggregation‐induced emission luminogens (AIEgens) in point‐of‐care (POC) diagnostics for disease biomarker detection. It systematically examines a range of biosensing platforms, including lateral flow immunoassays, microfluidic chips, and electrochemiluminescence sensors, alongside their utility in detecting ...
Danni Hu +3 more
wiley +1 more source
Architecture of the Baculovirus Nucleocapsid Revealed by Cryo-EM
, 2023 Baculovirus Autographa californica multiple nucleopolyhedrovirus (AcMNPV) has been widely used as a bioinsecticide and a protein expression vector. Despite their importance, very little is known about the structure of most baculovirus proteins.
Li, Yinyin +13 more
core +1 more source
OXCT1‐driven succinylation of PSMG3 stabilizes the proteasome to facilitate picornavirus replication
iMetaOmics, EarlyView.Upon entering the pig, foot‐and‐mouth disease virus (FMDV) regulates host glycolysis and the citrate cycle by modulating the expression of metabolic enzymes, resulting in changes in post‐translational modifications (PTMs) including succinylation, lactylation, crotonylation, acetylation, and phosphorylation.
Huisheng Liu +9 more
wiley +1 more source
Comparative Properties of Bacteriophage φ6 and φ6 Nucleocapsid [PDF]
, 1976 Nonionic detergent treatments released a nucleocapsid from the enveloped bacteriophage φ6. The nucleocapsid sedimented at nearly the same rate as the whole phage in sucrose density gradients, but the buoyant density in Cs2SO4 changed from 1.22 g/cm3 for ...
Vidaver, Anne +4 more
core
Interactions of Marburg Virus Nucleocapsid Proteins
Virology, 1998 In this study, the components of Marburg virus nucleocapsid complex were determined, and interactions between the compounds were investigated. Using salt dissociation of isolated virions, four proteins (NP, VP35, VP30, and L) remained attached to the core complex.
Becker, S. +4 more
openaire +2 more sources
Mixed lineage kinase 3 mediates SARS‐CoV‐2‐induced kidney injury via the Hsp70‐IL‐17A axis
Interdisciplinary Medicine, EarlyView.Kidney samples from patients infected with severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2) showed upregulated expression and activity of Mixed Lineage Kinase (MLK3). Based on the mechanistic studies, we identified MLK3 as a critical player in promoting SARS‐CoV‐2‐induced kidney injury.
Sandeep Kumar +18 more
wiley +1 more source
, 2013 SARS-CoV immunohistochemical staining of 293T cells transfected with spike (S), nucleocapsid (N), and spike, nucleocapsid, membrane, and envelope (SEMN) genes of SARS-CoV. Untransfected control is shown in the lower right photomicrograph.
Kwok H Chan (61037) +7 more
core +1 more source