Results 21 to 30 of about 3,660,966 (235)

Structural Basis for SARS-CoV-2 Nucleocapsid Protein Recognition by Single-Domain Antibodies

Frontiers in Immunology, 2021
The COVID-19 pandemic, caused by the coronavirus SARS-CoV-2, is the most severe public health event of the twenty-first century. While effective vaccines against SARS-CoV-2 have been developed, there remains an urgent need for diagnostics to quickly and ...
Qiaozhen Ye, Shan Lu, Kevin D. Corbett, Kevin D. Corbett   +3 more
doaj   +1 more source

Antibody Screening Results for Anti-Nucleocapsid Antibodies Towards the Development of a SARS-CoV-2 Nucleocapsid Protein Antigen Detecting Lateral Flow Assay [PDF]

, 2021
The global COVID-19 pandemic has created an urgent demand for large numbers of inexpensive, accurate, rapid, point-of-care diagnostic tests. Analyte-based assays are suitably inexpensive and can be rapidly mass-produced, but for sufficiently accurate ...
David, S. Boyle, Rafael, Rivera, John T, Connelly, Ben D, Grant, Ethan, Spencer, Sam A, Byrnes, H Gleda, Hermansky, Crissa, Bennett, Puneet K, Dewan, Joshua D, Bishop, Caitlin E, Anderson, Bernhard H, Weigl, Veronika, Glukhova, Helen, Hsieh, Kevin P, Nichols, David, Cate, Samantha, Kuhn, Ryan, Gallagher, Brianda, Barrios-Lopez   +18 more
core   +2 more sources

Hantavirus Nucleocapsid Protein Oligomerization [PDF]

Journal of Virology, 2001
ABSTRACT Hantaviruses are enveloped, negative-strand RNA viruses which can be lethal to humans, causing either a hemorrhagic fever with renal syndrome or a hantaviral pulmonary syndrome. The viral genomes consist of three RNA segments: the L segment encodes the viral polymerase, the M segment encodes the viral surface glycoproteins G1 and G2,
A, Alfadhli, Z, Love, B, Arvidson, J, Seeds, J, Willey, E, Barklis   +5 more
openaire   +2 more sources

Function of a retrotransposon nucleocapsid protein [PDF]

RNA Biology, 2010
Long terminal repeat (LTR) retrotransposons are not only the ancient predecessors of retroviruses, but they constitute significant fractions of the genomes of many eukaryotic species. Studies of their structure and function are motivated by opportunities to gain insight into common functions of retroviruses and retrotransposons, diverse mechanisms of ...
Sandmeyer, Suzanne B, Clemens, Kristina A   +1 more
openaire   +4 more sources

A computational method for predicting nucleocapsid protein in retroviruses [PDF]

Scientific Reports, 2022
AbstractNucleocapsid protein (NC) in the group-specific antigen (gag) of retrovirus is essential in the interactions of most retroviral gag proteins with RNAs. Computational method to predict NCs would benefit subsequent structure analysis and functional study on them.
Manyun Guo, Yucheng Ma, Wanyuan Liu, Zuyi Yuan   +3 more
openaire   +3 more sources

Analysing the impact of the two most common SARS-CoV-2 nucleocapsid protein variants on interactions with membrane protein in silico

Journal of Genetic Engineering and Biotechnology, 2021
As the body of scientific research focusing on the severe acute respiratory syndrome coronavirus 2 or SARS-CoV-2 continues to grow, several mutations have been reported as very common across the globe.
Syeda Tasnim Quayum, Saam Hasan
doaj   +1 more source

Baculovirus AC102 is a nucleocapsid protein that is crucial for nuclear actin polymerization and nucleocapsid morphogenesis [PDF]

Journal of Virology, 2018
ABSTRACT The baculovirus Autographa californica multiple nucleopolyhedrovirus (AcMNPV), the type species of alphabaculoviruses, is an enveloped DNA virus that infects lepidopteran insects and is commonly known as a vector for protein expression and cell transduction.
Hepp, Susan E., Borgo, Gina M., Ticau, Simina, Ohkawa, Taro, Welch, Matthew D.   +4 more
openaire   +4 more sources

Nucleocapsid Structure of Negative Strand RNA Virus

Viruses, 2020
Negative strand RNA viruses (NSVs) include many important human pathogens, such as influenza virus, Ebola virus, and rabies virus. One of the unique characteristics that NSVs share is the assembly of the nucleocapsid and its role in viral RNA synthesis ...
Ming Luo, James Ross Terrell, Shelby Ashlyn Mcmanus   +2 more
doaj   +1 more source

Subcellular localization of the porcine deltacoronavirus nucleocapsid protein [PDF]

Virus Genes, 2020
Porcine deltacoronavirus (PDCoV) has been recently identified as an emerging enteropathogenic coronavirus that mainly infects newborn piglets and causes enteritis, diarrhea and high mortality. Although coronavirus N proteins have multifarious activities, the subcellular localization of the PDCoV N protein is still unknown.
Zhen Ding, Suxian Luo, Wang Gong, Leyi Wang, Nengshui Ding, Jun Chen, Jiajia Chen, Ting Wang, Yu Ye, Deping Song, Lingbao Kong, Jinghua Zhang, Yuxing Tang   +12 more
openaire   +2 more sources

Comparison of Six Immunoassays for Assaying Levels of Immunoglobulin G against the Nucleocapsid and Spike Proteins of SARS-CoV-2 [PDF]

Journal of Clinical and Diagnostic Research, 2022
Introduction: Assay kits for detection of Immunoglobulin G (IgG) against the nucleocapsid protein (anti-nucleocapsid IgG) and spike proteins (anti-spike IgG) of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) were commercially provided by ...
Itsumi Suda, Takao Kimura, Takahiko Niwa, Katsuhiko Tsunekawa, Osamu Araki, Kunio Yanagisawa, Yutaka Tokue, Masami Murakami   +7 more
doaj   +1 more source