Results 1 to 10 of about 91,885 (305)

Adeno-associated virus type 2 (AAV2) uncoating is a stepwise process and is linked to structural reorganization of the nucleolus.

PLoS Pathogens, 2022
Nucleoli are membrane-less structures located within the nucleus and are known to be involved in many cellular functions, including stress response and cell cycle regulation. Besides, many viruses can employ the nucleolus or nucleolar proteins to promote
Sereina O Sutter, Anouk Lkharrazi, Elisabeth M Schraner, Kevin Michaelsen, Anita Felicitas Meier, Jennifer Marx, Bernd Vogt, Hildegard Büning, Cornel Fraefel   +8 more
doaj   +3 more sources

Systematic analysis of A-to-I RNA editing upon release of ADAR from the nucleolus. [PDF]

RNA Biol
Adenosine-to-inosine (A-to-I) RNA editing, catalysed by two ADAR isoforms (p110 and p150) and ADARB1, is a critical regulatory step in gene expression.
Lattuca R, Bascetin R, Detours V, Lafontaine DLJ.   +3 more
europepmc   +2 more sources

HAND2 invades nucleolar condensates to pioneer lineage-specific cardiac pacemaker gene programs. [PDF]

Nat Commun
Although best known as the site for ribosome assembly, the nucleolus organizes heterochromatin into transcriptionally repressed Nucleolus-Associated Domains (NADs).
Kulkarni K, Quinn G, Dela Rosa J, Goetsch S, Pandit V, Wang L, Sakaguchi A, Sivakumar S, Munshi NV.   +8 more
europepmc   +2 more sources

Nucleolus, Ribosomes, and Cancer [PDF]

American Journal of Pathology, 2008
Lorenzo Montanaro
exaly   +2 more sources

Space explorers need to be space farmers: What we know and what we need to know about plant growth in space

Mètode Science Studies Journal: Annual Review, 2021
Space exploration will require life support systems, in which plants can provide nutrients, oxygen, moisture, and psychological well-being and eliminate wastes. In alien environments, plants must adapt to a different gravity force, even the zero gravity
F. Javier Medina
doaj   +1 more source

Recent transcriptomic studies to elucidate the plant adaptive response to spaceflight and to simulated space environments

iScience, 2022
Summary: Discovering the adaptation mechanisms of plants to the space environment is essential for supporting human space exploration. Transcriptomic analyses allow the identification of adaptation response pathways by detecting changes in gene ...
Aránzazu Manzano, Eugénie Carnero-Diaz, Raúl Herranz, F. Javier Medina   +3 more
doaj   +1 more source

Manipulation of Cellular Processes via Nucleolus Hijaking in the Course of Viral Infection in Mammals

Cells, 2021
Due to their exceptional simplicity of organization, viruses rely on the resources, molecular mechanisms, macromolecular complexes, regulatory pathways, and functional compartments of the host cell for an effective infection process.
Olga V. Iarovaia, Elena S. Ioudinkova, Artem K. Velichko, Sergey V. Razin   +3 more
doaj   +1 more source

Fibrillarin-GFP Facilitates the Identification of Meiotic Competent Oocytes

Frontiers in Cell and Developmental Biology, 2021
The nucleolus undergoes significant functional changes and plays important roles during mammalian oocyte meiotic maturation. Fibrillarin (FBL) is the component of nucleolar small nuclear ribonucleoprotein (snRNP) particle and localizes to the dense ...
Ting Wang, Ting Wang, Jie Na
doaj   +1 more source

Beyond ribosome biogenesis: noncoding nucleolar RNAs in physiology and tumor biology

Nucleus, 2023
The nucleolus, the largest subcompartment of the nucleus, stands out from the nucleoplasm due to its exceptionally high local RNA and low DNA concentrations.
Nuray Böğürcü-Seidel, Nadja Ritschel, Till Acker, Attila Németh   +3 more
doaj   +1 more source

The structure of the mitotic spindle and nucleolus during mitosis in the amebo-flagellate Naegleria. [PDF]

PLoS ONE, 2012
Mitosis in the amebo-flagellate Naegleria pringsheimi is acentrosomal and closed (the nuclear membrane does not break down). The large central nucleolus, which occupies about 20% of the nuclear volume, persists throughout the cell cycle.
Charles J Walsh
doaj   +1 more source