Results 1 to 10 of about 79,372 (334)

Nucleolar origins: challenging perspectives on evolution and function. [PDF]

Open Biol
The nucleolus, once considered a mere ‘ribosome factory’, is now recognized as a dynamic hub influencing nearly every aspect of cellular life, from genome organization to stress response and ageing.
Muñoz-Velasco I, Herrera-Escamilla AK, Vázquez-Salazar A.   +2 more
europepmc   +2 more sources

Space explorers need to be space farmers: What we know and what we need to know about plant growth in space

Mètode Science Studies Journal: Annual Review, 2021
Space exploration will require life support systems, in which plants can provide nutrients, oxygen, moisture, and psychological well-being and eliminate wastes. In alien environments, plants must adapt to a different gravity force, even the zero gravity
F. Javier Medina
doaj   +1 more source

Manipulation of Cellular Processes via Nucleolus Hijaking in the Course of Viral Infection in Mammals

Cells, 2021
Due to their exceptional simplicity of organization, viruses rely on the resources, molecular mechanisms, macromolecular complexes, regulatory pathways, and functional compartments of the host cell for an effective infection process.
Olga V. Iarovaia, Elena S. Ioudinkova, Artem K. Velichko, Sergey V. Razin   +3 more
doaj   +1 more source

Beyond ribosome biogenesis: noncoding nucleolar RNAs in physiology and tumor biology

Nucleus, 2023
The nucleolus, the largest subcompartment of the nucleus, stands out from the nucleoplasm due to its exceptionally high local RNA and low DNA concentrations.
Nuray Böğürcü-Seidel, Nadja Ritschel, Till Acker, Attila Németh   +3 more
doaj   +1 more source

The structure of the mitotic spindle and nucleolus during mitosis in the amebo-flagellate Naegleria. [PDF]

PLoS ONE, 2012
Mitosis in the amebo-flagellate Naegleria pringsheimi is acentrosomal and closed (the nuclear membrane does not break down). The large central nucleolus, which occupies about 20% of the nuclear volume, persists throughout the cell cycle.
Charles J Walsh
doaj   +1 more source

Fibrillarin-GFP Facilitates the Identification of Meiotic Competent Oocytes

Frontiers in Cell and Developmental Biology, 2021
The nucleolus undergoes significant functional changes and plays important roles during mammalian oocyte meiotic maturation. Fibrillarin (FBL) is the component of nucleolar small nuclear ribonucleoprotein (snRNP) particle and localizes to the dense ...
Ting Wang, Ting Wang, Jie Na
doaj   +1 more source

The enteropathogenic E. coli effector EspF targets and disrupts the nucleolus by a process regulated by mitochondrial dysfunction. [PDF]

PLoS Pathogens, 2010
The nucleolus is a multifunctional structure within the nucleus of eukaryotic cells and is the primary site of ribosome biogenesis. Almost all viruses target and disrupt the nucleolus--a feature exclusive to this pathogen group. Here, using a combination
Paul Dean, Jon A Scott, Andrew A Knox, Sabine Quitard, Nicholas J Watkins, Brendan Kenny   +5 more
doaj   +1 more source

Distinct dynamics of the nucleolus in response to nutrient availability and during development in the rice blast fungus

mBio, 2023
The nucleolus has emerged as a central hub for nuclear functions in eukaryotes. Studies in mammals and the model yeast Saccharomyces cerevisiae showed that the nucleolus is pivotal to nuclear functions other than ribosome biogenesis.
Eunbyeol Cho, Song Hee Lee, Ralph A. Dean, Junhyun Jeon   +3 more
doaj   +1 more source

Nucleolar Proteome Analysis and Proteasomal Activity Assays Reveal a Link between Nucleolus and 26S Proteasome in A. thaliana

Frontiers in Plant Science, 2017
In all eukaryotic cells, the nucleolus is functionally and structurally linked to rRNA synthesis and ribosome biogenesis. This compartment contains as well factors involved in other cellular activities, but the functional interconnection between non ...
Charlotte Montacié, Charlotte Montacié, Nathalie Durut, Nathalie Durut, Alison Opsomer, Denise Palm, Pascale Comella, Pascale Comella, Claire Picart, Claire Picart, Marie-Christine Carpentier, Marie-Christine Carpentier, Frederic Pontvianne, Frederic Pontvianne, Christine Carapito, Enrico Schleiff, Julio Sáez-Vásquez, Julio Sáez-Vásquez   +17 more
doaj   +1 more source

Nucleolar Organization and Functions in Health and Disease

Cells, 2020
The nucleolus is a prominent, membraneless compartment found within the nucleus of eukaryotic cells. It forms around ribosomal RNA (rRNA) genes, where it coordinates the transcription, processing, and packaging of rRNA to produce ribosomal subunits ...
Ursula Stochaj, Stephanie C. Weber
doaj   +1 more source