Results 11 to 20 of about 79,372 (334)
Current Opinion in Cell Biology, 1994 The transcriptionally active rRNA genes have the remarkable ability to organize and integrate the biochemical pathway of ribosome production into a structural framework, the nucleolus. The past year has seen numerous advances in our understanding of the relationships between nucleolar substructures, the site of ribosomal RNA (rRNA) gene transcription ...
Scheer, Ulrich, Weisenberger, Dieter
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Histochemistry and Cell Biology, 2018 The nucleolus as site of ribosome biogenesis holds a pivotal role in cell metabolism. It is composed of ribosomal DNA (rDNA), which is present as tandem arrays located in nucleolus organizer regions (NORs). In interphase cells, rDNA can be found inside and adjacent to nucleoli and the location is indicative for transcriptional activity of ribosomal ...
Christian Schöfer, Klara Weipoltshammer
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Mathematical Methods of Operations Research, 2017 This paper analyzes the 1-nucleolus and, in particular, its relation to the nucleolus. It is seen that, contrary to the nucleolus, the 1-nucleolus can be computed in polynomial time due to a characterization using a combination of standard bankruptcy rules for associated bankruptcy problems. Sufficient conditions on a compromise stable game are derived
A. Estévez-Fernández +4 more
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The F-actin filament capping protein CapG is a bona fide nucleolar protein [PDF]
, 2008 Actin works in concert with myosin I to regulate the transcription of ribosomal genes in the nucleolus. Recently, nucleolar actin has been shown to be active in its polymeric form raising the question how actin dynamics is regulated in the nucleolus ...
Gettemans, Jan +3 more
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Studies on the relation between heme and nucleic acid syntheses in erythroid cell. 3. Nucleolus of erythroblast, changes in relation with cell specialization [PDF]
, 1969 The disappearance of nucleolus has been traced in the rat erythroid cells in relation with the cell specialization under varying conditions, i. e. in anemia with or without treatment by bromouracil and aminopterin.
Shigehisa, Morio
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Cold Spring Harbor Perspectives in Biology, 2010 When cells are observed by phase contrast microscopy, nucleoli are among the most conspicuous structures. The nucleolus was formally described between 1835 and 1839, but it was another century before it was discovered to be associated with a specific chromosomal locus, thus defining it as a cytogenetic entity. Nucleoli were first isolated in the 1950s,
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A Wiring of the Human Nucleolus [PDF]
Molecular Cell, 2006 Recent proteomic efforts have created an extensive inventory of the human nucleolar proteome. However, approximately 30% of the identified proteins lack functional annotation. We present an approach of assigning function to uncharacterized nucleolar proteins by data integration coupled to a machine-learning method.
Hinsby, Anders M. +8 more
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Nucleolar accumulation of RNA binding proteins induced by Actinomycin D is functional in Trypanosoma cruzi and Leishmania mexicana but not in T. brucei. [PDF]
PLoS ONE, 2011 We have recently shown in T. cruzi that a group of RNA Binding Proteins (RBPs), involved in mRNA metabolism, are accumulated into the nucleolus in response to Actinomycin D (ActD) treatment. In this work, we have extended our analysis to other members of
Ezequiel Názer, Daniel O Sánchez
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