Results 31 to 40 of about 72,696 (188)

Bioorthogonal Postlabeling Reveals Nuclear Localization of a Highly Cytotoxic Half‐Sandwich Ir(III) Tetrazine Complex in Live Cells

open access: yesChemBioChem, EarlyView.
This study reports the synthesis of five tetrazine‐coordinated, half‐sandwich iridium complexes and extensively describe their reactivity. Live cell fluorescent bioorthogonal labeling reveals the nuclear tropism of the most cytotoxic complex. Intracellular imaging of anticancer metallodrugs often relies on prelabeling with organic fluorophores, which ...
Alfonso Annunziata   +6 more
wiley   +1 more source

Peptidomimetics Targeting the Amyloidogenicity of Nucleophosmin 1 Mutations in Acute Myeloid Leukemia

open access: yesChemBioChem, Accepted Article.
Nucleophosmin 1(NPM1) is an abundant human protein endowed with many functions whose dysregulation leads to various cancers and mutations are relevant in Acute Myeloid Leukemia (AML). In the wild type form, pentameric NPM1 resides mainly in the nucleolus even if it shuttles toward the cytosol exerting its chaperon function, conversely in AML‐mutated ...
Daniele Florio   +7 more
wiley   +1 more source

A Nucleolus for Stochastic Cooperative Games [PDF]

open access: yes
This paper extends the definition of the nucleolus to stochastic cooperative games, that is, to cooperative games with random payoffs to the coalitions.
Suijs, J.P.M.
core   +1 more source

The nucleolus of directed acyclic graph games [PDF]

open access: yes, 2013
In this paper we consider a natural generalization of standard tree games where the underlying structure is a directed acyclic graph. We analyze the properties of the game and illustrate its relation with other graph based cost games.
Fleiner, Tamás   +2 more
core  

Upstream-binding factor is sequestered into herpes simplex virus type 1 replication compartments [PDF]

open access: yes, 2009
Previous reports have shown that adenovirus recruits nucleolar protein upstream-binding factor (UBF) into adenovirus DNA replication centres. Here, we report that despite having a different mode of viral DNA replication, herpes simplex virus type 1 (HSV ...
Ahmed   +25 more
core   +2 more sources

Recent Cutting‐Edge Technologies for the Delivery of Peptide Nucleic Acid

open access: yesChemistry – A European Journal, EarlyView.
This review provides an overview of PNA cellular delivery methods, starting with traditional peptide‐based systems and progressing to advanced approaches using nanoparticles, liposomes, and calixarene. It highlights how these innovative strategies have opened the way for more effective and efficient PNA delivery, ultimately enhancing the potential for ...
Concetta Avitabile   +4 more
wiley   +1 more source

A noncooperative view on two consistent aiport cost sharing rules [PDF]

open access: yes
This paper provides a noncooperative understanding of the nucleolus and the egalitarian allocation for airport cost problems. We find that every Nash equilibrium of the noncooperative game has the nucleolus as outcome while the egalitarian allocation is ...
Arin Aguirre, Francisco Javier   +2 more
core  

AKT regulates NPM dependent ARF localization and p53mut stability in tumors [PDF]

open access: yes, 2014
Nucleophosmin (NPM) is known to regulate ARF subcellular localization and MDM2 activity in response to oncogenic stress, though the precise mechanism has remained elusive.
Abraham, Aswin G.   +12 more
core   +2 more sources

A Case Series and Literature Review of Angiosarcoma With Malignant Effusion—A Challenging Cytologic Diagnosis With Dire Prognostic Implications

open access: yesDiagnostic Cytopathology, Volume 53, Issue 7, Page E119-E126, July 2025.
ABSTRACT Angiosarcoma with malignant effusion is an uncommon yet clinically aggressive presentation, which poses as a diagnostic pitfall with its overlapping cytomorphologic features with metastatic adenocarcinoma. In this article, two cases reported in the literature were reviewed for cytology, immunocytochemistry, and clinical course.
Jamie C. Y. Lam   +3 more
wiley   +1 more source

Nucleolus vs nucleus count for identifying spiral ganglion in human temporal bone [PDF]

open access: yes, 2018
OBJECTIVES: Spiral ganglion (SG) counting is used in experimental studies conducted on age-, noise-, and drug-induced sensorineural hearing loss, as well as in the assessment of cochlear implant performances.
Antonio Della Volpe,   +7 more
core   +1 more source

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