Results 141 to 150 of about 146,762 (298)

Cancer incidence in people with HIV in Italy: Comparison of the ICONA COHORT with general population data

open access: yesInternational Journal of Cancer, EarlyView.
What's New? Immune suppression induced by HIV infection significantly increases the risk of certain cancers among people with HIV (PWH). In the present study, the authors investigated cancer incidence among HIV‐infected individuals in Italy using data from the Italian Cohort Naïve Antiretrovirals. Comparison with the corresponding general population in
Pierluca Piselli   +243 more
wiley   +1 more source

In Vitro and Clinical Evaluations of UGT1A1‐, P‐gp‐, OATP1B1‐, and BCRP‐Mediated Drug–Drug Interactions of Belumosudil, a Potent ROCK2 Inhibitor

open access: yesThe Journal of Clinical Pharmacology, EarlyView.
Abstract Belumosudil is an oral selective rho‐associated coiled‐coil containing protein kinase 2 inhibitor, approved as a treatment for chronic graft‐versus‐host disease. Prior clinical studies demonstrated that coadministration with strong CYP3A4 inducers or proton pump inhibitors requires dose modification of belumosudil.
Olivier Schueller   +4 more
wiley   +1 more source

Two avian Plasmodium species trigger different transcriptional responses on their vector Culex pipiens

open access: yesMolecular Ecology, EarlyView., 2023
Abstract Malaria is a mosquito‐borne disease caused by protozoans of the genus Plasmodium that affects both humans and wildlife. The fitness consequences of infections by avian malaria are well known in birds, however, little information exists on its impact on mosquitoes.
Marta Garrigós   +4 more
wiley   +1 more source

Drug resistance mutations and phylogenetic analysis of HIV-1 subtypes B and F from mothers and children with vertical transmission. [PDF]

open access: yesBMC Infect Dis
Luz AL   +8 more
europepmc   +1 more source

Evidence of the Presence of 1-Phosphohistidine as the Main Phosphorylated Component at the Active Site of Bovine Liver Nucleoside Diphosphate Kinase. [PDF]

open access: bronze, 1969
Olov Wålinder   +7 more
openalex   +1 more source

Clinical Evaluation of Drug–Drug Interactions Between Bictegravir and Strong Inhibitors/Inducers of the CYP3A4, UGT1A1, or P‐gp Pathways

open access: yesThe Journal of Clinical Pharmacology, EarlyView.
Abstract In addition to antiretroviral therapy (ART), people with HIV often take medications to treat comorbidities. It is therefore important to assess these medications for potential drug‐drug interactions, which may affect the safety and efficacy of ART. Three phase I studies were conducted in adult participants without HIV. The pharmacokinetics (PK)
Priyanka Arora   +4 more
wiley   +1 more source

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