Results 141 to 150 of about 174,887 (292)

Isomorphic Fluorescent Nucleosides

Accounts of Chemical Research
In 1960, Weber prophesied that "There are many ways in which the properties of the excited state can be utilized to study points of ignorance of the structure and function of proteins". This has been realized, illustrating that an intrinsic and highly responsive fluorophore such as tryptophan can alter the course of an entire scientific discipline. But
openaire   +4 more sources

Thermometer Ions, Internal Energies, and In‐Source Fragmentation in Ambient Ionization

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Ionization and fragmentation are at the core of mass spectrometry. But they are not necessarily separated in space, as in‐source fragmentation can also occur. Here, we survey the literature published since our 2005 review on the internal energy and fragmentation in electrospray ionization sources.
Emilie Bertrand, Valérie Gabelica
wiley   +1 more source

Two-photon excitation enables single-molecule detection of a fluorescent base analogue in DNA with high photostability. [PDF]

Chem Sci
Sansom HG, Bailie AE, Stefanou F, Purse BW, Jones AC, Magennis SW.   +5 more
europepmc   +1 more source

NME1 (NME/NM23 nucleoside diphosphate kinase 1)

, 2013
ML Lacombe, Mathieu Boissan
openalex   +2 more sources

Emerging Therapeutic Strategies in Anti‐Aging Medicine: A Comprehensive Review

Medicine Bulletin, EarlyView.
ABSTRACT Aging is orchestrated by interconnected hallmarks such as genomic instability, mitochondrial dysfunction, cellular senescence, and disrupted intercellular communication, which collectively drive chronic disease progression. Recent advances have expanded therapeutic opportunities to include pharmacological agents, gene and epigenome editing ...
Yundong Peng, Rui Li, Huan Li, Jun Zhou, Xuanshi Liu, Guilherme Valente, Tatiana de Campos Melo, Sifan Chen, Lei Gu   +8 more
wiley   +1 more source

5-Phosphoribosyl 1-pyrophosphate synthetase converts the acyclic nucleoside phosphonates 9-(3-hydroxy-2-phosphonylmethoxypropyl)adenine and 9-(2-phosphonylmethoxyethyl)adenine directly to their antivirally active diphosphate derivatives

, 1991
Jan Balzarini, Erik De Clercq
openalex   +1 more source

Protection against herpes simplex virus type 2 infection in a neonatal murine model using a trivalent nucleoside-modified mRNA in lipid nanoparticle vaccine

, 2020
Philip LaTourette, Sita Awasthi, Angela Desmond, Norbert Pardi, Gary H. Cohen, Drew Weissman, Harvey M. Friedman   +6 more
openalex   +2 more sources

The cdc 22 Mutation in Schizosaccharomyces pombe is a Temperature‐Sensitive Defect in Nucleoside Diphosphokinase [PDF]

, 1981
John R. Dickinson
openalex   +1 more source

The ketogenic diet alters microbiome‐metabolome profiles to improve West syndrome therapy

Pediatric Investigation, EarlyView.
The ketogenic diet alleviates West syndrome by reshaping gut microbiota (increasing Bacteroides, Parabacteroides, and reducing Escherichia and Bifidobacterium), and modulating metabolites—including anticonvulsant lipids (e.g., capric acid), suppressed harmful lipids (e.g., 2‐methylbutyroylcarnitine), and amino acids and analogs (e.g., 3‐sulfinoalanine)—
Gan Xie, Qian Zhou, Jianxiang Liao, Yuejie Zheng, Wenjian Wang, Kunling Shen   +5 more
wiley   +1 more source

Adipose tissue releases nucleosides. [PDF]

Am J Physiol Cell Physiol
Zhang J, Le T, Ruiz-Torres V, Cohen M, Paharkova V, Abt E, Alnajjar HS, Tan J, Rashid K, Jones AE, Ball AB, Divakaruni AS, Paszkiewicz RL, Bandaru P, Mack JJ, Ashby JW, Kim J, Li G, Radu CG, Mittelman SD.   +19 more
europepmc   +1 more source