Results 171 to 180 of about 171,665 (294)

Bavachalcone targets transferrin receptor and sensitizes gemcitabine to affect bladder cancer progression

open access: yesiMeta, EarlyView.
Transferrin (Tf) binds extracellular Fe3+ and interacts with transferrin receptor (TFRC) on the cell membrane, leading to endocytosis. Iron is reduced by STEAP3, transported by DMT1 into the cytoplasm, then enters mitochondria to support Fe–S cluster formation, mitochondrial respiration, and ATP production.
Zihao Zhang   +21 more
wiley   +1 more source

Pediococcus acidilactici GR-5 alleviates hyperuricemia by degrading purine nucleosides and improving gut microbiota metabolism. [PDF]

open access: yesNPJ Sci Food
Ji J   +9 more
europepmc   +1 more source

Nanomaterial‐Enhanced Electrochemical Sensors for Clinical Monitoring of Acyclovir: Integration Into Molecular Diagnostics

open access: yesJournal of Clinical Laboratory Analysis, EarlyView.
Schematic illustration of biosensor technology for detection of ACV. ABSTRACT Objective This study investigates the innovative application of nanomaterial‐based micro‐devices aimed at enhancing the diagnosis and management of acyclovir (ACV) for herpes virus infections, specifically those caused by HSV‐1, HSV‐2, CMV, and VZV.
Mohammad Darvishi   +5 more
wiley   +1 more source

Nucleosides and Related Substances

open access: bronze, 1964
Kônoshin Onodera   +2 more
openalex   +2 more sources

Chemoselective Difluoromethylation of Nucleosides. [PDF]

open access: yesOrg Lett
Linden O   +3 more
europepmc   +1 more source

Clinical Evaluation of Drug–Drug Interactions Between Bictegravir and Strong Inhibitors/Inducers of the CYP3A4, UGT1A1, or P‐gp Pathways

open access: yesThe Journal of Clinical Pharmacology, EarlyView.
Abstract In addition to antiretroviral therapy (ART), people with HIV often take medications to treat comorbidities. It is therefore important to assess these medications for potential drug‐drug interactions, which may affect the safety and efficacy of ART. Three phase I studies were conducted in adult participants without HIV. The pharmacokinetics (PK)
Priyanka Arora   +4 more
wiley   +1 more source

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