Results 171 to 180 of about 174,887 (292)

The discovery of crotonoside as a nucleoside analogue demonstrates its potential to inhibit acute myeloid leukemia  activity through multiple pathways [PDF]

Chenchen Ma, Jingyi Wang
openalex   +1 more source

Multifunctional Porous Microshuttles as Scaffolding Components and Carriers of Bioactive Factors in Self‐Assembled Microtissues

Small, EarlyView.
This study introduces multifunctional, bioactive factor‐loaded porous microshuttles fabricated via a one‐step emulsification and chemical etching method. The poly(lactic‐co‐glycolic acid) microshuttles, featuring tunable pore sizes, enable loading and release of bioactive factors, and thereby enhance osteogenic marker expression and promote endothelial
Ke Song, Francesca Giacomini, Esra Güben Kaçmaz, Pamela Habibović, Roman Truckenmüller, Zeinab Niloofar Tahmasebi Birgani   +5 more
wiley   +1 more source

National representative survey of pretreatment HIV drug resistance in Colombia: analysis of antiretroviral resistance-associated mutations using next-generation sequencing. [PDF]

J Antimicrob Chemother
Martínez-Buitrago E, Zapata-Marín AF, Rubiano LC, Sañudo LM, Oñate JM, Lenis W, García-Góez JF, Álvarez JE, García-Morales C, Matías-Florentino M, Ávila-Ríos S.   +10 more
europepmc   +1 more source

Light‐Guided Molecular Patterning for High‐Throughput Single‐Molecule Mechanical Characterization

Small, EarlyView.
A light‐guided molecular patterning method is presented for high‐throughput single‐molecule characterization. The approach enables scalable and accessible molecular patterning without specialized lithography equipment. Patterned surfaces are compatible with downstream biophysical assays, demonstrated by magnetic tweezers and flow‐based single‐molecule ...
Hansol Choi, Andrew Ward, Wesley P. Wong
wiley   +1 more source

Stereodivergent access to α- and β-azanucleosides <i>via</i> catalyst-free, achiral modulator-controlled iodocyclization: a concise synthesis of forodesine. [PDF]

Chem Sci
Zhong Y, Zeng J, Li M, Liang Y, Guan S, Zhao K, Mu J, Tang P, Wang H, Chen F.   +9 more
europepmc   +1 more source

Evaluation of purine-nucleoside degrading ability and in vivo uric acid lowering of Streptococcus thermophilus IDCC 2201, a novel antiuricemia strain

Dayoung Kim, Jin Seok Moon, Ji Eun Kim, Ye-Ji Jang, Han Sol Choi, Ikhoon Oh   +5 more
openalex   +1 more source

Flexoelectric Polarization‐Enhanced Gd‐Based Nanoflowers for Efficient Phosphatase‐Mimicking Dephosphorylation

Small Structures, EarlyView.
Flexoelectric polarization is harnessed to dynamically enhance phosphatase‐mimicking catalysis in Gd‐based nanoflowers, enabling ultrasound‐responsive and efficient biophosphate ester hydrolysis through strain‐induced electronic modulation. Phosphatase‐mimicking nanozymes provide highly stable enzyme‐like activity but remain limited by their static ...
Linjing Su, Jingyan Xu, Rong Huang, Jinlan Liao, Lixue Zhao, Ling Li, Zhi Zhang, Yuhao Xiong   +7 more
wiley   +1 more source

A nucleoside transporter on the mitochondria of T. gondii is essential for maintaining normal growth of the parasite. [PDF]

Parasit Vectors
Qian J, Guo L, Yang Y, He Z, He M, Chen C, Luo Y, Xu J, Li S, Fang R.   +9 more
europepmc   +1 more source

Recent Advances in Bioconjugation of Aromatic Amino Acid Residues by a Reactivity‐Guided Approach

The Chemical Record, EarlyView.
This review highlights recent advances in the bioconjugation of aromatic amino acids residues, focusing on strategies that leverage their inherent chemical reactivity to enable precise and versatile modifications of biomacromolecules, illustrating relevant applications.
Bruno M. da S. Santos, Lívia C. R. M. da Frota, Thais G. Silva, Fernanda G. Finelli   +3 more
wiley   +1 more source

ToxPoint: The case for Equilibrative Nucleoside Transporters in current regulatory guidance. [PDF]

Toxicol Sci
Martinez-Guerrero L, Tang X, Ekins S, Wright SH, Cherrington NJ.   +4 more
europepmc   +1 more source