Results 41 to 50 of about 313,454 (314)
Carbamate-Based Bolaamphiphile as Low-Molecular-Weight Hydrogelators
Gels, 2016 A new bolaamphiphile analog featuring carbamate moieties was synthesized in six steps starting from thymidine. The amphiphile structure exhibits nucleoside-sugar polar heads attached to a hydrophobic spacer via carbamate (urethane) functions.
Laurent Latxague +5 more
doaj +1 more source
Structure Characterization of Escherichia coli Pseudouridine Kinase PsuK
Frontiers in Microbiology, 2022 Pseudouridine (Ψ) is one of the most abundant RNA modifications in cellular RNAs that post-transcriptionally impact many aspects of RNA. However, the metabolic fate of modified RNA nucleotides has long been a question. A pseudouridine kinase (PsuK) and a
Xiaojia Li +7 more
doaj +1 more source
Moving breathers in bent DNA with realistic parameters [PDF]
Mod. Phys. Lett. B. 18(25):1319-1326, 2004, 2004 Recent papers have considered moving breathers (MBs) in DNA models including long range interaction due to the dipole moments of the hydrogen bonds. We have recalculated the value of the charge transfer when hydrogen bonds stretch using quantum chemical methods which takes into account the whole nucleoside pairs.
arxiv +1 more source
Nature Communications, 2018 Currently available influenza virus vaccines have inadequate effectiveness and are reformulated annually due to viral antigenic drift. Thus, development of a vaccine that confers long-term protective immunity against antigenically distant influenza virus
N. Pardi +13 more
semanticscholar +1 more source
eLife, 2014 Concentrative nucleoside transporters (CNTs) are responsible for cellular entry of nucleosides, which serve as precursors to nucleic acids and act as signaling molecules. CNTs also play a crucial role in the uptake of nucleoside-derived drugs, including anticancer and antiviral agents.
Minhee Lee +6 more
openaire +4 more sources
Nucleic Acid Based Fluorinated Derivatives: New Tools for Biomedical Applications
Applied Sciences, 2012 Nucleic acid-based fluorinated derivatives, e.g., nucleosides or oligonucleotides connected to highly fluorinated chains or labeled with one or more fluorine atoms, have been investigated recently due to their high potential for biomedical applications ...
Christel Dolain +3 more
doaj +1 more source
Mesoscopic modeling for nucleic acid chain dynamics [PDF]
Phys. Rev. E, 71 art. num. 051902 (2005), 2005 To gain a deeper insight into cellular processes such as transcription and translation, one needs to uncover the mechanisms controlling the configurational changes of nucleic acids. As a step toward this aim, we present here a novel mesoscopic-level computational model that provides a new window into nucleic acid dynamics.
arxiv +1 more source
Determination of total potentially available nucleosides in bovine milk [PDF]
, 2010 Bovine colostrum and milk samples were collected from two herds over the course of the first month post-partum, pooled for each herd by stage of lactation and total potentially available nucleosides were determined.
Gill, Brendon D. +2 more
core +2 more sources
Mechanochemistry of nucleosides, nucleotides and related materials
Beilstein Journal of Organic Chemistry, 2018 The application of mechanical force to induce the formation and cleavage of covalent bonds is a rapidly developing field within organic chemistry which has particular value in reducing or eliminating solvent usage, enhancing reaction rates and also in ...
Olga Eguaogie +4 more
doaj +1 more source
Pharmaceuticals, 2017 Tumor suppressor genes can be silenced genetically as well as epigenetically. One approach to reversing epigenetic suppression of tumor suppressor genes is to inhibit DNA methyl transferase.
Richard Daifuku +2 more
doaj +1 more source