Results 91 to 100 of about 42,345 (197)

Charge Transfer-oxy Radical Mechanism for Anti-cancer Agents [PDF]

open access: yes, 1986
The proposal is advanced that anti-cancer drugs generally function by charge transfer resulting in formation of toxic oxy radicals which destroy the neoplasm.
Ames, James R.   +5 more
core   +1 more source

Antiviral treatment for chronic hepatitis B virus infection--immune modulation or viral suppression? [PDF]

open access: yes, 2006
The availability of nucleoside analogues has broadened treatment options for chronic hepatitis B virus (HBV ) infection. Registered treatment for chronic hepatitis B currently consists of (pegylated) interferon, lamivudine and adefovir,
Buster, E.H.C.J. (Erik)   +1 more
core   +2 more sources

Phylogenetic Analysis and Emerging Drug Resistance against Different Nucleoside Analogues in Hepatitis B Virus Positive Patients. [PDF]

open access: yesMicroorganisms, 2023
Gohar M   +7 more
europepmc   +1 more source

Infectivity decline of an RNA plant virus by increased mutagenesis supports the lethal defection model in vivo [PDF]

open access: yes, 2013
Lethal mutagenesis is a new antiviral therapy based on increasing the mutation rate by using mutagenic base and nucleoside analogues whose molecular mechanisms are not fully understood.
Brichette Mieg, Isabel   +2 more
core  

Template polymerization of nucleotide analogues [PDF]

open access: yes
Recent work on the template-directed reactions of the natural D-nucleotides has made it clear that l-nucleotides and nucleotide-like derivatives of other sugars would strongly inhibit the formation of long oligonucleotides.
Orgel, L. E.
core   +1 more source

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