Charge Transfer-oxy Radical Mechanism for Anti-cancer Agents [PDF]
The proposal is advanced that anti-cancer drugs generally function by charge transfer resulting in formation of toxic oxy radicals which destroy the neoplasm.
Ames, James R. +5 more
core +1 more source
Antiviral treatment for chronic hepatitis B virus infection--immune modulation or viral suppression? [PDF]
The availability of nucleoside analogues has broadened treatment options for chronic hepatitis B virus (HBV ) infection. Registered treatment for chronic hepatitis B currently consists of (pegylated) interferon, lamivudine and adefovir,
Buster, E.H.C.J. (Erik) +1 more
core +2 more sources
Synthesis and photophysical characterization of fluorescent indole nucleoside analogues. [PDF]
Sawyer JM, Passow KT, Harki DA.
europepmc +1 more source
Air pollution impede ALT normalization in chronic hepatitis B patients treated with nucleotide/nucleoside analogues. [PDF]
Jang TY +5 more
europepmc +1 more source
Phylogenetic Analysis and Emerging Drug Resistance against Different Nucleoside Analogues in Hepatitis B Virus Positive Patients. [PDF]
Gohar M +7 more
europepmc +1 more source
Watson-Crick Base Pairing of N-Methoxy-1,3-Oxazinane (MOANA) Nucleoside Analogues within Double-Helical DNA. [PDF]
Afari MNK +3 more
europepmc +1 more source
Infectivity decline of an RNA plant virus by increased mutagenesis supports the lethal defection model in vivo [PDF]
Lethal mutagenesis is a new antiviral therapy based on increasing the mutation rate by using mutagenic base and nucleoside analogues whose molecular mechanisms are not fully understood.
Brichette Mieg, Isabel +2 more
core
Anti-HSV nucleoside and non-nucleoside analogues: spectroscopic characterisation of naphthyl and coumarinyl amides and their mode and mechanism of antiviral action. [PDF]
Das Mahapatra A +4 more
europepmc +1 more source
Template polymerization of nucleotide analogues [PDF]
Recent work on the template-directed reactions of the natural D-nucleotides has made it clear that l-nucleotides and nucleotide-like derivatives of other sugars would strongly inhibit the formation of long oligonucleotides.
Orgel, L. E.
core +1 more source

