Results 101 to 110 of about 58,095 (298)

Clinical significance and prognostic value of urinary nucleosides in breast cancer patients

open access: yes, 2005
Objective: Thirteen urinary nucleosides, primarily degradation products of tRNA, were evaluated as potential tumor markers for breast cancer ...
Kong, HW   +5 more
core   +1 more source

SYNTHESIS OF 2'-DEOXYHEXOSYLADENINE NUCLEOSIDES.

open access: yes, 1970
SYNTHESIS OF 2'-DEOXYHEXOSYLADENINE ...
DAVID HART. WARNOCK (7989071)
core   +4 more sources

Oligonucleotides containing disaccharide nucleosides: synthesis, physicochemical, and substrate properties

open access: yes, 2003
The efficient synthesis of oligonucleotides containing 2'-O-beta-D-ribofuranosyl (and beta-D-ribopyranosyl)nucleosides, 2'-O-alpha-D-arabinofuranosyl (and alpha-L-arabinofurano syl)nucleosides, 2'-O-beta-D-erythrofuranosylnucleosides, and 2'-O-(5'-amino ...
Efimtseva, E.V.   +9 more
core   +1 more source

The tRNA‐Modification Geranyl‐2‐Thiouridine Enables RNA‐Lipid Association

open access: yesAngewandte Chemie International Edition, EarlyView.
We report the preparation of mono‐ to tri‐geranylated RNA and the association of the hydrophobic RNA with membranes for future efficient incorporation of RNA into liposomes. ABSTRACT The packaging of RNA in lipid nanoparticles for protection and delivery was key for the development of mRNA vaccines and therapeutics. Formulation requires the addition of
Johannes Singer   +3 more
wiley   +1 more source

Synthesis, reactivity and biological activity of 5-alkoxymethyluracil analogues

open access: yesBeilstein Journal of Organic Chemistry, 2011
This review article summarizes the results of a long-term investigation of 5-alkoxymethyluracil analogues and is aimed, in particular, at methods of syntheses.
Lucie Brulikova, Jan Hlavac
doaj   +1 more source

Biological Activity Profile of Triazolylpurine Nucleosides

open access: yes
The biological activity of novel 2,6-bis-(1,2,3-triazol-1-yl)purine, N6-substituted-2-(1,2,3-triazol-1-yl)adenine and 6-alkyl/arylthio-2-(1,2,3-triazol-1-yl)purine nucleosides were studied.
Petrovska, Ramona   +5 more
core  

Asymmetric synthesis of novel pseudo-D-vinylcyclopropyl nucleosides bearing quaternary carbon as potential anti-herpesvirus agent

open access: yes, 2017
Pseudo-d-vinylcyclopropyl nucleosides 10-12 bearing a quaternary carbon were designed and synthesized starting from (R)-epichlorohydrin using a tandem reaction of double alkylation and lactonization via oxirane-ring opening reaction, a Wittig reaction ...
정낙신
core   +1 more source

Synthesis and Properties of Ditriazolylpurine Nucleosides

open access: yes
The synthesis of new 2,6-bis-ditriazolylpurine nucleosides is described and reactions with different nucleophiles ...
Bižāne, Inga   +7 more
core  

The enzymatic and chemical synthesis of nucleoside analogues using N-deoxyribosyltransferase from Lactobacillus leichmannii [PDF]

open access: yes
N-deoxyribosyltransferase catalyses the transfer of 2-deoxy-I 2.3, -dideoxyand 2,5-dideoxyribose sugars between purine and pyrimidine bases. In this work, a crude extract of N-deoxyribosyltransferase from Lactobacillus leichmannii was used in the ...
Hicks, Nicola
core  

Crown ether ring-fused nucleosides: synthesis and conformational properties

open access: yes, 2008
We here describe the synthesis of a series of novel bicyclic ribonucleoside derivatives, with 18-crown-6 ether moieties attached via their ribose 2- and 3-positions, as first examples of crown ether ring-fused nucleosides, to be evaluated as antiviral ...
J. D’Onofrio   +4 more
core   +1 more source

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