RESEARCHES ON PYRIMIDINES. LXXXIV. THE TRANSFORMATION BY HYDROLYSIS OF SECONDARY PYRIMIDINE NUCLEOSIDES INTO IMIDAZOL COMBINATIONS. [PDF]
, 1917 Treat B. Johnson, Sidney E. Hadley
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Angewandte Chemie International Edition, EarlyView.This review highlights mechanochemical strategies for the late‐stage modification of active pharmaceutical ingredients (APIs), providing a valuable resource for selecting substrates to evaluate the pharmaceutical potential of novel and existing (mechano)chemical protocols.
Johanna Templ, Lars Borchardt
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AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury
, 2022 Hepatology, EarlyView.
Robert J. Fontana +6 more
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Second generation silver(I)-mediated imidazole base pairs
Beilstein Journal of Organic Chemistry, 2014 The imidazole–Ag(I)–imidazole base pair is one of the best-investigated artificial metal-mediated base pairs. We show here that its stability can be further improved by formally replacing the imidazole moiety by a 2-methylimidazole or 4-methylimidazole ...
Susanne Hensel +3 more
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Isolation and Separation of the Pyrimidine Nucleosides of Yeast Ribosenucleic Acid [PDF]
, 1948 R. J. C. Harris, J. F. Thomas
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Inhibition of adenovirus serotype 14 infection by octadecyloxyethyl esters of (S)-[(3-hydroxy-2-phosphonomethoxy)propyl]- nucleosides in vitro. [PDF]
, 2018 On September 22, 2008, a physician on Prince of Wales Island, Alaska, notified the Alaska Department of Health and Social Services (ADHSS) of an unusually high number of adult patients with recently diagnosed pneumonia (n = 10), including three persons ...
Barnard, Dale L +8 more
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Influence of a fluorobenzene nucleobase analogue on the conformational flexibility of RNA studied by molecular dynamics simulations [PDF]
, 2006 Chemically modified bases are frequently used to stabilize nucleic acids, to study the driving forces for nucleic acid structure formation and to tune DNA and RNA hybridization conditions.
Engels, Joachim W. (Prof. Dr.) +1 more
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Inter‐Nanoparticle FRET for Biosensing: Photophysics Versus Size
Angewandte Chemie International Edition, EarlyView.Förster resonance energy transfer (FRET) systems with luminescent nanoparticles (NPs) as donors and acceptors (inter‐NP FRET) combine unique photophysical properties with large sizes. This review discusses the influence of NP type, architecture, surface chemistry, and optical properties on FRET and the pros and cons of inter‐NP FRET for bioanalytical ...
Eduard Madirov +3 more
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The Origin of the Feedstock Molecules for Life on the Hadean Earth
Angewandte Chemie International Edition, EarlyView.The origin of life in the Hadean eon required the formation of amino acids and nucleosides among the key molecules of life. In an often postulated strongly reducing atmosphere, HCN and its derivatives are robustly formed as plausible starting molecules. But HCN does not form in a Hadean, weakly reducing atmosphere.
Nikolai Diukarev +6 more
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