Results 141 to 150 of about 58,095 (298)

Reactivity Studies of 2,6-Ditriazolylpurine Nucleosides with Nucleophiles

Reaction of 2,6-ditriazolylpurine nucleosides with nucleophiles is mild and efficient route to C6 derivatization of purine base. To explore scope and limitations of the method, we studied reactivity of various N- and S-nucleophiles as well as kinetics ...
Bizdēna, Ērika, Novosjolova, Irina, Kovaļovs, Armands, Turks, Māris   +3 more
core  

Nucleoside Antibiotics

Journal of Biological Chemistry, 1968
Bruce M. Chassy, R.J. Suhadolnik
openaire   +1 more source

Cordycepin mediates neuroprotection against apoptosis via ERK/CREB signaling activation in Aβ1–42‐induced neuronal cell models

Ibrain, Volume 11, Issue 1, Page 84-97, Spring 2025.
This study demonstrates cordycepin's neuroprotective effects against Aβ1–42‐induced apoptosis in neuronal cells, mediated through the activation of the extracellular signal‐regulated kinase/cyclic AMP‐responsive element‐binding protein (ERK/CREB) signaling pathway.
Wenshu Zhou, Cheng Wang, Yige Tan, Philip Lazarovici, Xiaoyan Wen, Shaoping Li, Wenhua Zheng   +6 more
wiley   +1 more source

Clinical performance of sFlt‐1/PlGF ratio triage in suspected pre‐eclampsia: A prospective, observational multicenter diagnostic‐triage study in South Africa (TsHEPPO study)

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective To evaluate the diagnostic and short‐term predictive performance of the soluble fms‐like tyrosine kinase‐1/placental growth factor (sFlt‐1/PlGF ratio) in South African women with suspected pre‐eclampsia (PE), comparing thresholds of ≥ 33 and ≥ 38 in a predominantly African population.
Ismail Bhorat, Priya Soma‐Pillay, Lawrence Chauke, Mushi Matjila, Tshidi Sebitloane, Nitalia Naidoo, Manu Vatish   +6 more
wiley   +1 more source

Continuous UV irradiation played an inconclusive role in selecting the canonical genetic alphabet. [PDF]

Proc Natl Acad Sci U S A
Jusino-Maldonado M, Platten WC, Wolfe HJ, Todd ZR.   +3 more
europepmc   +1 more source

Noncanonical Nucleotides in the Genome Around the Maternal‐Zygotic Transition

Journal of Experimental Zoology Part B: Molecular and Developmental Evolution, EarlyView.
In this paper, Kazzazi et al. provide a comprehensive review of the dynamics of nonconventional nucleotides in the genome during early developmental stages, hypothesizing a potential role for these nucleotides in the activation of the zygotic genome. ABSTRACT From the very moment of fertilization and throughout development, the cells of animal embryos ...
Latifa Kazzazy, Dávid Mező, Kinga K. Nagy, Viktória Perey‐Simon, Judit Tóth, Angéla Békési, Beáta Vértessy, Máté Varga   +7 more
wiley   +1 more source

Integrating UHPLC-MS and MALDI-MSI for Spatial Nucleoside Profiling in FFPE Breast Cancer: A Multimodal Molecular Pathology Framework. [PDF]

Anal Chem
Wu J, Geisberger S, Mastrobuoni G, Lisek K, Raimundo S, Nebrich G, Grzeski M, Rajewsky N, Klauschen F, Klein O, Kempa S.   +10 more
europepmc   +1 more source

Effects of mixed microbial fermentation on the quality and metabolite profile of cassava leaf feed based on untargeted metabolomics

JSFA reports, EarlyView.
Abstract Background Cassava leaves are a major byproduct of cassava processing and have a low utilization rate. In this study, Lactiplantibacillus plantarum, Saccharomyces cerevisiae, and Bacillus subtilis were used for solid‐state fermentation of cassava leaves to improve their feed quality. Results After 48 h of fermentation, the feed pH decreased to
Mengjun Zhou, Dongxiu Wang, jie Zhang, Jian Chen, Xuding Wen   +4 more
wiley   +1 more source

Polyphenol dietary supplementation prevents inflammation‐induced muscle atrophy in a zebrafish (Danio rerio) model

Journal of the Science of Food and Agriculture, EarlyView.
Abstract BACKGROUND Diet‐induced inflammation is a major cause of muscle degeneration impacting human and animal health. Owing to their anti‐inflammatory and antioxidant properties, polyphenols have attracted considerable interest as feed additives.
Graziella Orso, Monica Matuozzo, Mariapina Rocco, Seyed Hossein Hoseinifar, Ghasem Ashouri, Andrea Scaloni, Marina Paolucci, Chiara D'Ambrosio, Roberta Imperatore   +8 more
wiley   +1 more source

Approaching life in a test tube with prebiotic chemistry. [PDF]

Commun Chem
Pianowski ZL.
europepmc   +1 more source