Results 161 to 170 of about 151,614 (341)

Identification of Candidate Blood Biomarkers of Recombinant Human Erythropoietin Administration Using Targeted Polar Metabolomics by HILIC‐MS/MS

open access: yesDrug Testing and Analysis, EarlyView.
Using targeted HILIC‐MS/MS metabolomics, inosine and hypoxanthine were identified as potential biomarkers of EPO administration. Their consistent and sensitive plasma responses highlight their promise for inclusion in the Athlete Biological Passport (ABP), warranting further investigation to enhance anti‐doping detection strategies. ABSTRACT Increasing
Olivier Salamin   +5 more
wiley   +1 more source

Pediococcus acidilactici GR-5 alleviates hyperuricemia by degrading purine nucleosides and improving gut microbiota metabolism. [PDF]

open access: yesNPJ Sci Food
Ji J   +9 more
europepmc   +1 more source

Spiro[3.3]heptane: A Versatile sp3‐Rich Scaffold and its Synthetic Routes

open access: yesEuropean Journal of Organic Chemistry, EarlyView.
The sp3‐rich spiro[3.3]heptane scaffold is a saturated, 3D bioisostere of benzene. This review summarizes key synthetic strategies, including [2+2] cyclizations and bond disconnections at C1C2 or C4 (spiro‐carbon) positions, offering a practical guide for accessing this emerging motif and expanding drug‐like chemical space.
Myunggi Jung
wiley   +1 more source

Identification of methylated nucleosides in messenger RNA from Novikoff hepatoma cells.

open access: yesProceedings of the National Academy of Sciences of the United States of America, 1974
R. Desrosiers, K. Friderici, F. Rottman
semanticscholar   +1 more source

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