Results 171 to 180 of about 36,245 (244)

Calibration and discrimination ability of the Dat'AIDS score in people living with HIV aged 70 years and older from the Dat'AIDS cohort

open access: yesHIV Medicine, EarlyView.
Abstract Objective The Dat'AIDS score was developed to predict 5‐year mortality risk in people living with HIV aged 60 and older. However, its validity in people living with HIV aged 70 years and older needed confirmation. Methods This was a multicentre prospective cohort study in the Dat'AIDS French cohort.
Abeo Mousse   +337 more
wiley   +1 more source

The impact of accumulating immune adaptation in circulating strains of HIV‐1

open access: yesHIV Medicine, EarlyView.
Abstract Background Mutations in human immunodeficiency virus type 1 (HIV‐1) enable the virus to evade recognition and killing by human leucocyte antigen (HLA)‐restricted T cells. These viral adaptations are specific to the HLA type of individuals and are therefore evident as HLA allele‐HIV sequence associations at the population level. Most studies of
Marwah Al‐kaabi   +7 more
wiley   +1 more source

Real‐world use of second‐generation integrase strand transfer inhibitors (INSTI) as switch therapy in the prospective ANRS‐CO3‐AquiVIH‐NA cohort

open access: yesHIV Medicine, EarlyView.
Abstract Objectives To characterize real‐world treatment switching in France to bictegravir (BIC or B) or dolutegravir (DTG)‐based regimens with a focus on treatment persistence, effectiveness (HIV‐1 RNA ≤50 copies/ml) and particular attention to the prevalence and incidence of comorbidities. Methods People living with HIV from the prospective ANRS‐CO3‐
O. Leleux   +15 more
wiley   +1 more source

Pediococcus acidilactici GR-5 alleviates hyperuricemia by degrading purine nucleosides and improving gut microbiota metabolism. [PDF]

open access: yesNPJ Sci Food
Ji J   +9 more
europepmc   +1 more source

Postoperative Pain After Endodontic Treatment in HIV‐Positive Patients Under HAART: A Prospective Observational Cohort Study

open access: yesInternational Endodontic Journal, EarlyView.
ABSTRACT Aim To compare post‐operative pain following root canal treatment (RCT) in HIV‐positive patients receiving highly active antiretroviral therapy (HAART) and HIV‐negative patients and to assess the influence of systemic condition on endodontic pain.
Marcos Felipe Iparraguirre Nuñovero   +5 more
wiley   +1 more source

Age‐related differences in mRNA vaccine immunogenicity and adjuvancy

open access: yesImmunology &Cell Biology, EarlyView.
Older people often respond poorly to mRNA vaccines, with reduced T and B cell responses, but they also bear more morbidity and mortality for infectious diseases. This paper maps age‐related changes in mechanisms of adjuvancy that can shape the immunogenicity of mRNA vaccine in a mouse model. Created in BioRender.
Shivali Savita Chinni   +12 more
wiley   +1 more source

DNA Content and DNA Damage in Raw and Heat-Processed Foods. [PDF]

open access: yesJ Agric Food Chem
Shin J, Jaruga P, Dizdaroglu M, Kool ET.
europepmc   +1 more source

High Intrahepatic cccDNA in Resolved HBV Infection: Insights From Living Donor Liver Transplantation With Anti‐HBc‐Positive Grafts

open access: yesJournal of Gastroenterology and Hepatology, EarlyView.
ABSTRACT Aim In hepatitis B surface antigen (HBsAg)‐negative recipients with antibody to hepatitis B core antigen (anti‐HBc)‐positive liver grafts, hepatitis B virus (HBV) can be reactivated under post‐transplant immunosuppression. We recently reported a median intrahepatic covalently closed circular DNA (cccDNA) level of 238 copies/μg in HBsAg ...
Sung Kwan Bae   +15 more
wiley   +1 more source

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