Results 11 to 20 of about 119,298 (337)
Insights into the Mycosphere Fungal Community and Its Association with Nucleoside Accumulation in Ophiocordyceps sinensis [PDF]
Journal of FungiSoil microbiomes are critical environmental factors influencing the occurrence and quality formation of Ophiocordyceps sinensis, a valuable medicinal fungus endemic to the Qinghai-Tibet Plateau. However, few studies have explored the relationship between
Jianshuang Zhang +5 more
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Molecules, 2022 In our attempt towards the synthesis and development of effective antimicrobial, anticancer and antioxidant agents, a novel series of 2,3-dihydropyrido[2,3-d]pyrimidin-4-one 7a–e and pyrrolo[2,1-b][1,3]benzothiazoles 9a–e were synthesized.
Aamal A. Al-Mutairi +3 more
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COMPLEX-FORMING PROPERTIES OF SYNTHETIC PYRIMIDINONE NUCLEOSIDES WITH Ag(I) IONS IN AN AQUEOUS SOLUTION [PDF]
Acta Poloniae Pharmaceutica, 2023 The present work describes the complexation properties of two synthetic nucleosides (used as ligands), i.e. β-D-ribofuranoside-4-pyrimidinone (ribo) and β-D-deoxyribofuranoside-4-pyrimidinone (deoxy) with Ag(I) ions in aqueous solution.
Marek Pająk +5 more
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Sensors, 2006 A rigid molecular clip comprising bisphosphonate binding sites and aromaticsidewalls forming an electron-rich cavity is able to distinguish between nucleosides andnucleotides in aqueous solution. Neutral nucleosides as well as antibiotics derived thereofare drawn into the unpolar interior of the cleft and lead to substantial upfield-shifts in the 1HNMR
Fokkens, Michael +2 more
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SOME RECENT FINDINGS IN THE BIOTECHNOLOGY OF BIOLOGICALLY IMPORTANT NUCLEOSIDES [PDF]
Biotechnologia Acta, 2013 Some recent findings in the biotechnology of biologically important nucleosides will be discussed, viz., (i) a new strategy of the cascade one-pot transformation of D-pentoses into nucleosides based on the extension and deepening of the knowledge of the ...
A. Mikhailopulo, A. I. Miroshnikov
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Green Synthesis and Catalysis, 2020 Both O-glycosides and nucleosides are essential biomolecules with important roles in a variety of biological processes. Chemical synthesis of both O-glycosides and nucleosides is a scalable and reliable method to develop new therapeutic agents and ...
Penghua Li +7 more
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Radiosensitizing Nucleosides [PDF]
JNCI Journal of the National Cancer Institute, 1996 Chemotherapeutic drugs that perturb nucleotide metabolism have the potential to produce substantial sensitization of tumor cells to radiation treatment. The process is called radiosensitization, and the agents that induce it are called radiosensitizers.
C J, McGinn, D S, Shewach, T S, Lawrence
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Efficient Biocatalytic Synthesis of Dihalogenated Purine Nucleoside Analogues Applying Thermodynamic Calculations [PDF]
, 2020 The enzymatic synthesis of nucleoside analogues has been shown to be a sustainable and efficient alternative to chemical synthesis routes. In this study, dihalogenated nucleoside analogues were produced by thermostable nucleoside phosphorylases in ...
Giessmann, Robert T. +9 more
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Strained Conformations of Nucleosides in Active Sites of Nucleoside Phosphorylases
Biomolecules, 2020 Nucleoside phosphorylases catalyze the reversible phosphorolysis of nucleosides to heterocyclic bases, giving α-d-ribose-1-phosphate or α-d-2-deoxyribose-1-phosphate. These enzymes are involved in salvage pathways of nucleoside biosynthesis. The level of
Irina A. Il’icheva +2 more
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Testicular disposition of clofarabine in rats is dependent on equilibrative nucleoside transporters
Pharmacology Research & Perspectives, 2021 Acute lymphoblastic leukemia (ALL) is the most common cancer in children and adolescents. Although the 5‐year survival rate is high, some patients respond poorly to chemotherapy or have recurrence in locations such as the testis. The blood–testis barrier
Siennah R. Miller +7 more
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