Results 221 to 230 of about 193,772 (411)

Biologically Active Nucleosides [PDF]

Current Protocols in Nucleic Acid Chemistry, 2005
openaire   +11 more sources

Model‐Informed Drug Development Applications and Opportunities in mRNA‐LNP Therapeutics

Clinical Pharmacology &Therapeutics, EarlyView.
The utilization of lipid nanoparticles (LNP) for encapsulating mRNA has revolutionized the field of therapeutics, enabling the rapid development of COVID‐19 vaccines and cancer vaccines. However, the clinical development of mRNA‐LNP therapeutics faces numerous challenges due to their complex mechanisms of action and limited clinical experience.
Jiawei Zhou, Rohit Rao, Monica E. Shapiro, Nessy Tania, Cody Herron, Cynthia J. Musante, Jim H. Hughes   +6 more
wiley   +1 more source

On the Quest for Biomarkers: A Comprehensive Analysis of Modified Nucleosides in Ovarian Cancer Cell Lines. [PDF]

Cells
Mohl DA, Lagies S, Lonzer A, Pfäffle SP, Groß P, Benka M, Jäger M, Huber MC, Günther S, Plattner DA, Juhasz-Böss I, Backhaus C, Kammerer B.   +12 more
europepmc   +1 more source

Dideoxyapiose nucleosides revisited : syntheses and protide derivatives [PDF]

, 2011
Balzarini, Jan, Toti, Kiran, Van Calenbergh, Serge   +2 more
core   +1 more source

Studies on Nucleosides and Nucleotides. VIII. Nucleophilic Substitution of Secondary Sulfonyloxy Groups of Pyrimidine Nucleosides. (1)

, 1968
Tateaki Naito, Miyoshi Hirata, Yoshiaki Nakai, Toshihiko Kobayashi, M. KANAO   +4 more
openalex   +2 more sources

New Glycoconjugates Containing Selenium and Polyphenols. Stereoselective Synthesis by Pummerer‐like Rearrangement.

European Journal of Organic Chemistry, EarlyView.
Two series of novel six‐membered Se‐glycoconjugates containing hydroxycinnamic acids marked by well‐known antioxidant properties are synthesized, exploiting a Mitsunobu reaction and a Pummerer‐like rearrangement. A first example of six‐membered selenosugar with selenium in the ring and bearing an acetal‐like functional group at C‐1 was reported, which ...
Claudia González, Mauro De Nisco, Reinier Lemos, Giovanna Cimmino, Yoana Pérez‐Badell, Severina Pacifico, Silvana Pedatella   +6 more
wiley   +1 more source

UCK2-dependent conversion of cytidine to CTP is required for CTP uptake by <i>Chlamydia trachomatis</i>. [PDF]

MicroPubl Biol
Blanchet L, Subtil A.
europepmc   +1 more source

Contactless Conductivity Detection for Capillary Electrophoresis—Developments From 2020 to 2024

ELECTROPHORESIS, EarlyView.
ABSTRACT The review covering the development of capillary electrophoresis with capacitively coupled contactless conductivity detection from 2020 to 2024 is the latest in a series going back to 2004. The article considers applications employing conventional capillaries and planar lab‐on‐chip devices as well as fundamental and technical developments of ...
Peter C. Hauser, Pavel Kubáň
wiley   +1 more source

Comprehensive Analysis of Small RNA Modifications in <i>Arabidopsis thaliana</i> and Their Dynamics During Seed Germination. [PDF]

Metabolites
Jiang LC, Men M, Cui XJ, Zeng RJ, Gu SY, Feng T, Zeng C, Ye T, Xiong J, Yuan BF, Feng YQ.   +10 more
europepmc   +1 more source

BASIS OF ACTINOMYCIN ACTION, II. EFFECT OF ACTINOMYCIN ON THE NUCLEOSIDE TRIPHOSPHATE-INORGANIC PYROPHOSPHATE EXCHANGE

, 1963
I. Goldberg, Murray Rabinowitz, E. Reich
openalex   +1 more source