Results 221 to 230 of about 151,614 (341)

5'-Guanidino Xylofuranosyl Nucleosides as Novel Types of 5'-Functionalized Nucleosides with Biological Potential. [PDF]

Pharmaceuticals (Basel)
Szilagyi J, Moreira T, Nunes RS, Silva J, Alves C, Martins A, Alvariño R, Heise NV, Csuk R, Xavier NM.   +9 more
europepmc   +1 more source

A Population Pharmacokinetic Approach to Understand the Effect of Efavirenz on CYP3A Activity in Healthy Volunteers Using Midazolam as a Probe

CPT: Pharmacometrics &Systems Pharmacology, EarlyView.
ABSTRACT Efavirenz induces and inhibits multiple drug‐metabolizing enzymes, contributing to significant drug–drug interactions. This study quantified the impact of multiple doses of efavirenz on CYP3A activity via midazolam metabolism using a population pharmacokinetic approach.
Kimberly S. Collins, Blessed W. Aruldhas, Ingrid F. Metzger, Jessica B. L. Lu, Michael A. Heathman, Sara K. Quinney, Zeruesenay Desta   +6 more
wiley   +1 more source

ALKBH8-mediated formation of a novel diastereomeric pair of wobble nucleosides in mammalian tRNA.

Nature Communications, 2011
E. van den Born, C. Vågbø, Lene Songe-Møller, Vibeke Leihne, G. F. Lien, G. Leszczynska, A. Małkiewicz, H. Krokan, F. Kirpekar, A. Klungland, P. Falnes   +10 more
semanticscholar   +1 more source

On the Quest for Biomarkers: A Comprehensive Analysis of Modified Nucleosides in Ovarian Cancer Cell Lines. [PDF]

Cells
Mohl DA, Lagies S, Lonzer A, Pfäffle SP, Groß P, Benka M, Jäger M, Huber MC, Günther S, Plattner DA, Juhasz-Böss I, Backhaus C, Kammerer B.   +12 more
europepmc   +1 more source

Ashwagandha: Is It Safe? Part 2: A Preclinical Evidence Review

Phytotherapy Research, EarlyView.
ABSTRACT The preclinical evidence for the safety of ashwagandha (Withania somnifera (L.) Dunal, AS) is reviewed, and its preparations (extracts) and constituents, from the general toxicity in animal models to in vitro and cell culture studies, which may elucidate mechanisms of action and explain clinical case reports.
Elizabeth M. Williamson, Thomas Brendler
wiley   +1 more source

Preparation of nucleoside analogues: opportunities for innovation at the interface of synthetic chemistry and biocatalysis. [PDF]

Chem Sci
Salihovic A, Taladriz-Sender A, Burley GA.   +2 more
europepmc   +1 more source

Studies on Nucleosides and Nucleotides. V. A New Synthetic Method of Ribonucleotide. Part I. Synthesis of Theophylline-ribonucleotide by the Use of 1, 5Dihalogeno-derivative of D-Ribose

, 1960
金沢 定一
openalex   +2 more sources

Exploring the Fragmentation of Sodiated Species Involving Covalent‐Bond Cleavages for Metabolite Characterization

Rapid Communications in Mass Spectrometry, EarlyView.
ABSTRACT Rationale Electrospray (ESI), the most popular desorption/ionization technique used in mass spectrometry‐based metabolomics, generates both protonated and deprotonated molecules, as well as adduct ions, sodium being the most frequent monoatomic cation entering their composition.
Annelaure Damont, Ekaterina Darii, Chenqin Cao, Anaïs Legrand, Alain Perret, Sylvain Dechaumet, Amina S. Woods, Christophe Junot, Jean‐Claude Tabet, François Fenaille   +9 more
wiley   +1 more source

UCK2-dependent conversion of cytidine to CTP is required for CTP uptake by <i>Chlamydia trachomatis</i>. [PDF]

MicroPubl Biol
Blanchet L, Subtil A.
europepmc   +1 more source

Metabolisms of Nucleosides in Bacteria Part III

, 1966
Takuo Sakai, Tatsurokuro Tochikura, Kôichi Ogata   +2 more
openalex   +2 more sources