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Synthesis of Natural Product-Like Tricyclic Higher-Carbon Sugar Nucleosides
Because of the structural novelty and interesting biological profiles, the synthesis of higher-carbon sugars has been highly pursued. In this work, we first synthesized a series of structurally novel bis-uracil containing tricyclic higher-carbon sugar ...
Xiao-Han Yuan+4 more
doaj +1 more source
Determination of total potentially available nucleosides in bovine milk [PDF]
Bovine colostrum and milk samples were collected from two herds over the course of the first month post-partum, pooled for each herd by stage of lactation and total potentially available nucleosides were determined.
Gill, Brendon D.+2 more
core +2 more sources
An efficient and facile strategy has been developed for bromination of nucleosides using sodium monobromoisocyanurate (SMBI). Our methodology demonstrates bromination at the C-5 position of pyrimidine nucleosides and the C-8 position of purine ...
Roger Stromberg, Jyotirmoy Maity
doaj +1 more source
LC-MS based quantification of 2’-ribosylated nucleosides Ar(p) and Gr(p) in tRNA [PDF]
RNA nucleosides are often naturally modified into complex non-canonical structures with key biological functions. Here we report LC-MS quantification of the Ar(p) and Gr(p) 2'-ribosylated nucleosides in tRNA using deuterium labelled standards, and the ...
Agris+28 more
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Phosphorylation of purine and pyrimidine nucleosides by isolated rat liver mitochondria [PDF]
Formation of 5'-AMP, 5'-GMP, 5'-CMP and 5'UMP was confirmed in isolated rat liver mitochondria incubated with alpha-ketoglutarate, inorganic phosphate, purine nucleoside and pyrimidine nucleoside. Increased incorporation of 32Pi into ATP, GTP and UTP was
Inaba, Kozo, Oda, Takuzo
core +1 more source
Interaction of low-energy electrons with the purine bases, nucleosides, and nucleotides of DNA [PDF]
The authors report results from computational studies of the interaction of low-energy electrons with the purine bases of DNA, adenine and guanine, as well as with the associated nucleosides, deoxyadenosine and deoxyguanosine, and the nucleotide ...
McKoy, Vincent, Winstead, Carl
core +1 more source
Synthesis of Modified Nucleosides [PDF]
Peer Reviewed ; https://deepblue.lib.umich.edu/bitstream/2027.42/143685/1/cpnc0100 ...
Roger Jones, Piet Herdewijn
openaire +3 more sources
Background Modification of nucleosides on transfer RNA (tRNA) is important either for correct mRNA decoding process or for tRNA structural stabilization.
Youmei Wang+6 more
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Testicular disposition of clofarabine in rats is dependent on equilibrative nucleoside transporters
Acute lymphoblastic leukemia (ALL) is the most common cancer in children and adolescents. Although the 5‐year survival rate is high, some patients respond poorly to chemotherapy or have recurrence in locations such as the testis. The blood–testis barrier
Siennah R. Miller+7 more
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The morbidity and mortality of colorectal cancer (CRC) have been increasing in recent years, and early detection of CRC can improve the survival rate of patients. RNA methylation plays crucial roles in many biological processes and has been implicated in
Weifang Zheng+9 more
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