Results 151 to 160 of about 156,001 (374)

Elucidating the DNA–Histone Interaction in Nucleosome from the DNA–Dendrimer Complex [PDF]

open access: green, 2016
Yen‐Chih Huang   +7 more
openalex   +1 more source

An open call for contributions to a special issue of Biophysical Reviews focused on multiscale simulations of DNA from electrons to nucleosomes [PDF]

open access: green, 2023
Wilma K. Olson   +7 more
openalex   +1 more source

Regulation of R‐Loop Dynamics by Proteins and Long Noncoding RNAs: An Emerging Paradigm for Cancer Treatment

open access: yesCancer Science, EarlyView.
R‐loops are three‐stranded nucleic acid structures whose dysregulation leads to genomic instability and cancer progression. This review summarizes the protein and lncRNA machineries that regulate R‐loop dynamics and discusses the therapeutic potential of targeting these pathways in cancer.
Miho M. Suzuki   +3 more
wiley   +1 more source

Dynamic Reorganization of Nucleosome Positioning in Somatic Cells after Transfer into Porcine Enucleated Oocytes

open access: yesStem Cell Reports, 2017
Summary: The nucleosome, the fundamental structural unit of chromatin, is a critical regulator of gene expression. The mechanisms governing changes to nucleosome occupancy and positioning during somatic cell reprogramming remain poorly understood.
Chenyu Tao   +13 more
doaj   +1 more source

Catalytic Mechanism of the INO80 Chromatin Remodeler Acting on the Nucleosome [PDF]

open access: bronze, 2016
Marianne Schwarz   +2 more
openalex   +1 more source

Parental nucleosome segregation and the inheritance of cellular identity

open access: yesNature reviews genetics, 2021
Thelma M. Escobar   +2 more
semanticscholar   +1 more source

Structural and functional dissection of the WH2/DAD motif of INF2, a formin linked to human inherited degenerative disorders

open access: yesThe FEBS Journal, EarlyView.
The INF2 WH2/DAD domain, composed of hydrophobic and basic regions, forms a single α‐helix in solution. The hydrophobic segment is essential for INF2 function, as its deletion disrupts actin dynamics and causes nuclear abnormalities, like those seen in pathogenic INF2 DID variants. In contrast, natural INF2 WH2/DAD variants found in patients with renal
Leticia Labat‐de‐Hoz   +5 more
wiley   +1 more source

Nucleosome-bound SOX2 and SOX11 structures elucidate pioneer factor function

open access: yesNature, 2020
S. Dodonova   +4 more
semanticscholar   +1 more source

The importin‐alpha superfamily engages in ethylene signaling by shuttling ETHYLENE INSENSITIVE 2 from the endoplasmic reticulum to the nucleus

open access: yesThe FEBS Journal, EarlyView.
The plant hormone ethylene regulates plant growth, ripening, senescence, and stress responses. The hormonal signal transmission, from receptors at the ER membrane to the transcriptional regulators in the nucleus, is still not completely understood.
Fabian Wynen   +7 more
wiley   +1 more source

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