Results 151 to 160 of about 64,059 (299)

Nuclease digestion in between and within nucleosomes [PDF]

, 1976
W. Greil, Tibor Igo‐Kemenes, Hans G. Zachau   +2 more
openalex   +1 more source

A cellular model of TDP‐43 induces phosphorylated TDP‐43 aggregation with distinct changes in solubility and autophagy dysregulation

The FEBS Journal, EarlyView.
TDP‐43 protein plays a pathological role in sporadic and familial amyotrophic lateral sclerosis (ALS). Here, we developed a cellular model overexpressing TDP‐43 with three mutations linked to familial ALS, termed ‘3X‐TDP‐43’. Mutant 3X‐TDP‐43 expression showed deficits in autophagy flux and colocalization with stress granules.
Matthew B. Dopler, Muhammad I. Abeer, Sanaz Arezoumandan, Keyshawn Cox, Tyler L. Petersen, Esther H. Daniel, Carlton L. Cannon III, Angelica Bautista, Kennedy D. Blancher, Alysia M. Bland, Kylie J. Bond, Dominque A. Davis, Jessica M. Francois, Eliana J. McCray, Justin M. Morgan, Jessica L. Pulliam, Zymir A. Robinson, Mykia J. Taylor, James A. Dowell, Nigel J. Cairns, Michael A. Gitcho   +20 more
wiley   +1 more source

General regulatory factors exert differential effects on nucleosome sliding activity of the ISW1a complex

Biological Research
Background Chromatin dynamics is deeply involved in processes that require access to DNA, such as transcriptional regulation. Among the factors involved in chromatin dynamics at gene regulatory regions are general regulatory factors (GRFs). These factors
Andrea Oyarzún-Cisterna, Cristián Gidi, Fernanda Raiqueo, Roberto Amigo, Camila Rivas, Marcela Torrejón, José L. Gutiérrez   +6 more
doaj   +1 more source

Binding of cis - and trans -dichlorodiammineplatinum(II) to the nucleosome core

, 1979
Stephen J. Lippard, James D. Hoeschele
openalex   +1 more source

Statistical distributions of nucleosomes: nonrandom locations by a stochastic mechanism [PDF]

, 1988
Roger D. Kornberg, Lubert Stryer
openalex   +1 more source

Epigenetic control of cell identities from epiblast to gastrulation

The FEBS Journal, EarlyView.
In this review, we present and contextualize current knowledge about the roles of epigenetic modifiers during the development of mouse epiblast to gastrulation stage. The epigenetic regulation of enhancer and promoter elements by DNA methylation, histone modifications, and chromatin accessibility in concert with lineage‐specific transcription factors ...
Katrin M. Schüle, Simone Probst
wiley   +1 more source

Cell cycle-dependent changes in conformation and composition of nucleosomes containing human histone gene sequences [PDF]

, 1987
Richard Sterner, Lidia C. Boffa, Thelma A. Chen, Vincent G. Allfrey   +3 more
openalex   +1 more source

Interaction of TFAP2A with the Ku70/80 complex is crucial for HIF‐dependent activation of hypoxia‐inducible genes

The FEBS Journal, EarlyView.
Under normoxic conditions, the SUMOylated fraction of TFAP2A cannot interact with the Ku70/Ku80 complex, nor it can bind to chromatin. The unSUMOylated fraction pre‐occupies the chromatin of a subset of hypoxia‐induced genes together with the Ku70/Ku80 complex for basal euchromatin formation. Under hypoxic conditions, the SUMOylation equilibrium shifts
Amalia Kanoura, Antonis Giakountis, Chrysa Filippopoulou, Angeliki Karagiota, George Stamatakis, Martina Samiotaki, George Panayotou, George Simos, Georgia Chachami   +8 more
wiley   +1 more source

Nucleosome arrangement with regard to DNA base composition.

, 1979
Patrice Nelson, S.C. Albright, William T. Garrard   +2 more
openalex   +1 more source

Neutrophil Extracellular Traps Are Widely Distributed Across Lesional and Perilesional Hidradenitis Suppurativa Skin, and Elevated Serum NET Markers Associate With Moderate to Severe HS Disease

International Journal of Dermatology, EarlyView.
Increased NET markers are detected in HS skin and blood. Neutrophils are scarce in healthy skin but infiltrate lesions of hidradenitis suppurativa (HS) patients. Activated neutrophils release proinflammatory neutrophil extracellular traps (NETs). The NET marker CitH3 was widely distributed across both lesional and perilesional regions of HS skin but ...
Stephanie C. M. van Dalen, Josephine W. J. Stein, Tirza Bruurmijn, Martyn L. Foster, Renato G. S. Chirivi, Maarten van der Linden, Helmuth van Es, Jacek C. Szepietowski, Piotr K. Krajewski, Kelsey R. van Straalen, Errol P. Prens, John R. Ingram, Eric Meldrum   +12 more
wiley   +1 more source