Results 151 to 160 of about 141,257 (371)
The isolation of nucleosomes from saline‐washed chromatin [PDF]
L. Woodhead, E.W. Johns
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A basic motif anchoring ISWI to nucleosome acidic patch regulates nucleosome spacing
Recent studies have implicated the nucleosome acidic patch in the activity of ATP-dependent chromatin remodeling machines. We used a photocrosslinking-based nucleosome profiling technology (photoscanning) to identify a conserved basic motif within the ...
H. T. Dao+4 more
semanticscholar +1 more source
RepliChrom is an interpretable machine learning model that predicts enhancer‐promoter interactions using DNA replication timing across multiple cell types. By integrating replication timing with chromatin interaction data from multiple experimental platforms, it accurately distinguishes true interactions and reveals promoter‐region signals as key ...
Fuying Dao+7 more
wiley +1 more source
Characteristic H3 N-tail dynamics in the nucleosome core particle, nucleosome, and chromatosome
Summary: The nucleosome core particle (NCP) comprises a histone octamer, wrapped around by ∼146-bp DNA, while the nucleosome additionally contains linker DNA.
Ayako Furukawa+7 more
doaj
The basic unit of chromatin is the nucleosome, a histone octamer with 147 base pairs of DNA wrapped around it. Positions of nucleosomes relative to each other and to DNA elements have a strong impact on chromatin structure and gene activity and are ...
Zhongliang Zhao, Holger Bierhoff
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Supercoiling energy and nucleosome formation: the role of the arginine-rich histone kernel [PDF]
R. Daniel Camerini‐Otero+1 more
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Despite lacking DNMT3, EM‐seq revealed CpG methylation in the Colorado potato beetle. CUT&Tag analysis showed an association of H3K36me3 and H3K27ac with transcription, with H3K36me3 mirroring CpG methylation, demonstrating epigenetic flexibility.
Zoe M. Länger+6 more
wiley +1 more source
Free energy profile for unwrapping outer superhelical turn of CENP-A nucleosome
Eukaryotic genome is packaged in a nucleus in the form of chromatin. The fundamental structural unit of the chromatin is the protein-DNA complex, nucleosome, where DNA of about 150 bp is wrapped around a histone core almost twice.
Hidetoshi Kono+2 more
doaj +1 more source
Chromatin: The nucleosome unwrapped [PDF]
The structure of the nucleosome core particle has been determined by X-ray crystallography at 2.8 A resolution. The structure has several significant surprises, and provides important new insights into the structure and function of chromatin.
openaire +3 more sources
ATAC‐seq in Emerging Model Organisms: Challenges and Strategies
Principle of ATAC‐seq (left), overview of arthropod species with published ATAC‐seq data (middle), summary of experimental design (right). ABSTRACT The Assay for Transposase‐Accessible Chromatin with sequencing (ATAC‐seq) is a versatile and widely utilized method for identifying potential regulatory regions, such as promoters and enhancers, within a ...
Duğçar Ebrar Erdoğan+13 more
wiley +1 more source