Results 231 to 240 of about 72,215 (324)

Mechanistic Insights and Pharmacological Approaches for Nitrogen and Sulfur Mustards and Their Implications as Therapeutic Agents

open access: yesJournal of Applied Toxicology, Volume 45, Issue 8, Page 1417-1425, August 2025.
ABSTRACT Nitrogen and sulfur mustards, often acting as vesicants, have significant consequences for public health. Skin is a common site for exposure to these vesicants that can result in considerable morbidity and mortality. Given that the treatment options are limited, new insights into the mechanisms for the toxicity of these vesicants that can be ...
Madison Owens   +3 more
wiley   +1 more source

Quantitative spatial analysis of chromatin biomolecular condensates using cryoelectron tomography. [PDF]

open access: yesProc Natl Acad Sci U S A
Zhou H   +11 more
europepmc   +1 more source

Analyzing the Challenges and Opportunities Associated With Harnessing New Antibiotics From the Fungal Microbiome

open access: yesMicrobiologyOpen, Volume 14, Issue 4, August 2025.
Graphical abstract illustrating the multifaceted approach to harnessing fungal microbiome diversity for antibiotic discovery. Key elements include historical insights, modern genomic tools, and innovative biotechnological strategies for isolating and enhancing fungal antibiotic production.
Md. Sakhawat Hossain   +5 more
wiley   +1 more source

Compromised two-start zigzag chromatin folding in immature mouse retina cells driven by irregularly spaced nucleosomes with short DNA linkers. [PDF]

open access: yesNucleic Acids Res
Kable B   +7 more
europepmc   +1 more source

Genome‐Wide 5‐Methylcytosine and 5‐Hydroxymethylcytosine Signatures Analysis of Plasma Cell‐Free DNA in Schizophrenia

open access: yesMedComm, Volume 6, Issue 8, August 2025.
We performed cfDNA 5‐methylcytosine (5mC) and 5‐hydroxymethylcytosine (5hmC) sequencing of plasma samples from 66 individuals with SCZ and 77 healthy controls (HC). We identified differentially 5mC methylated regions (DMRs) and differentially 5hmC hydroxymethylated regions (DhMRs) that showed distinct patterns between SCZ and control samples.
Gang Xue   +13 more
wiley   +1 more source

Genome-wide maps of UV damage repair and mutation suppression by CPD photolyase. [PDF]

open access: yesNucleic Acids Res
Bohm KA   +4 more
europepmc   +1 more source

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