Results 211 to 220 of about 49,625 (309)

Altered benzo[a]pyrene adduct formation in nucleosomes establishes distinct mutational patterns in lung cancer. [PDF]

J Biol Chem
Morledge-Hampton B, Lindberg M, Larsson E, Wyrick JJ.   +3 more
europepmc   +1 more source

Bioanalytical TERS and Advanced Data Processing Methods

Journal of Raman Spectroscopy, Volume 57, Issue 6, Page 977-994, June 2026.
Tip‐enhanced Raman spectroscopy delivers label‐free, subnanometer vibrational imaging of biological systems. Recent advances in instrumentation, data analysis, and ambient/liquid operation enable surface‐selective mapping of molecular heterogeneity in proteins, nucleic acids, membranes, and viruses, positioning TERS as a powerful platform for nanoscale
Sarika Joshi, Ankit Dodla, Sarthak Saxena, Twinkle Soni, Sumit Saxena, Shobha Shukla, Bayden R. Wood   +6 more
wiley   +1 more source

Direct Readout of Multivalent Chromatin Reader-Nucleosome Interactions by Nucleosome Mass Spectrometry. [PDF]

ACS Cent Sci
Lee AS, Fisher NP, Marunde MR, Su P, Khan LF, Ezell RJ, Gillespie ZB, Graham B, Taylor HF, Onuoha UC, Su T, Jooß K, Schachner LF, Fuchs HA, Noll K, Meiners MJ, Cheek MA, Burg JM, Sun ZW, Musselman CA, Keogh MC, Kelleher NL.   +21 more
europepmc   +1 more source

Phase Separation‐Mediated SRF/P54nrb Transcription Complex Shapes the Vasculature Microenvironment via Upregulating OLFML3 in Glioblastoma

MedComm, Volume 7, Issue 6, June 2026.
We identified SRF as the key TF significantly associated with the malignant phenotype and poor prognosis of GBM. SRF forms a transcriptional complex with P54nrb via phase separation to upregulate the expression of OLFML3. OLFML3 activates ECs and promotes angiogenesis by degrading ECM, releasing proangiogenic factors, enhancing cell–cell adhesion, and ...
Zetao Chen, Yujie Zhang, Liwei Hao, Chenya Feng, Chuangyuan Wang, Tianjing Ai, Peiqian Hu, Jingsen Ji, Shengsong Fu, Taoliang Chen, Fabing Zhang, Liang Zhao, Yiquan Ke   +12 more
wiley   +1 more source

Linker histones consolidate heterogenous nucleosome fiber contacts by linking together multiple nucleosomes. [PDF]

Nat Commun
Adhireksan Z, Sharma D, Bao Q, Lee PL, Padavattan S, Davey GE, Hansen JC, Davey CA.   +7 more
europepmc   +1 more source

Epigenetic Regulation in Cardiovascular Diseases: Mechanisms and Therapeutic Targets

MedComm, Volume 7, Issue 6, June 2026.
Environmental and lifestyle exposures reshape the cardiovascular epigenome through coordinated regulation of DNA methylation, histone modifications, noncoding RNAs, and RNA methylation (m6A). These multilayered mechanisms drive enhancer‐centered regulatory network remodeling and epigenomic plasticity in cardiovascular diseases, highlighting emerging ...
Wangzheqi Zhang, Chenyang Mu, Rui Zhao, Runwei Ma, Xuehai Liu, Haoling Zhang, Zengwu Wang, Jing‐jing Zhang   +7 more
wiley   +1 more source

Structural analysis of OCT4 binding to human LIN28B nucleosomes. [PDF]

Sci Rep
Sinha KK, Halic M.
europepmc   +1 more source

White Adipose Tissue Browning and Cross Talk With Metabolic Diseases and Tumors: From Molecular Mechanisms to Clinical Translation

Med Research, Volume 2, Issue 2, Page 280-308, June 2026.
White adipose tissue undergoes browning under endogenous and exogenous stimuli, primarily regulated by core molecules such as PRDM16 and UCP1. It exhibits a double‐edged sword effect in metabolic diseases and tumors: while mitigating metabolic disease impacts and suppressing early‐stage tumors through nutritional competition, it may accelerate cachexia
Yingjiao Wang, Diyuan Zhang, Yuqin Zhou, Ling Qian, Yan Wang, Lei Peng, Min Zhao, Hao Tian, Zhenyu Wu, Aiqi Tang, Minghao Sun, Yi Zhang, Xiaowei Qi   +12 more
wiley   +1 more source

Nucleosome spacing regulates linker methylation by DNMT3A2/3B3. [PDF]

Mol Cell
Xie X, Liu M, Chua GNL, Zhou XE, Dykstra ML, Liu S, Jones PA, Worden EJ.   +7 more
europepmc   +1 more source

Nucleosome [PDF]

, 2020
openaire   +1 more source