Results 201 to 210 of about 10,982 (239)
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Spotlight on Nucleosomes

Nature Reviews Genetics, 2018
Two new studies in Nature provide insight into the role of nucleosomes in gene regulation. One describes the genome-wide organization of nucleosomes and the other details how transcription factor binding to DNA is affected by the presence of nucleosomes.
exaly   +3 more sources

Remodeling of Individual Nucleosomes in Nucleosome Arrays

Adenosin triphosphate (ATP)-dependent nucleosome remodeling factors sculpt the nucleosomal landscape of eukaryotic chromatin. They deposit, evict, or reposition nucleosomes along DNA in a process termed nucleosome sliding. Remodeling has traditionally been analyzed using mononucleosomes as a model substrate.
Petra, Vizjak   +2 more
openaire   +2 more sources

Nucleosome autoantibodies

Clinica Chimica Acta, 2006
The nucleosome is a large protein-nucleic acid complex involved in DNA packing and in controlling genetic information. Under circumstances described below, this component, normally sequestered in the cell nucleus, is released into the extracellular milieu and then is easily accessible to cells of the immune system.
openaire   +2 more sources

Nucleosomes in contact

Science, 2017
Structural Biology In eukaryotic cells, genomic DNA must be compacted to fit inside the nucleus. A key player in DNA packaging is the nucleosome, which comprises a segment of DNA wrapped around an octamer of histone proteins. During replication and transcription, nucleosomes must reposition themselves on the DNA.
openaire   +2 more sources

Dynamic nucleosomes

Chromosome Research, 2006
It is now widely recognized that the packaging of genomic DNA together with core histones, linker histones, and other functional proteins into chromatin profoundly influences nuclear processes such as transcription, replication, repair and recombination. How chromatin structure modulates the expression and maintenance of knowledge encoded in eukaryotic
openaire   +2 more sources

Nucleosome Mapping

2009
The basic repeating unit of chromatin, the nucleosome, is known to play a critical role in regulating the process of gene transcription. The positioning of nucleosomes on a promoter is a significant determinant in its responsiveness to gene-inducing signals.
Nicolas, GĂ©vry   +3 more
openaire   +2 more sources

The Nucleosome

Scientific American, 1981
R D, Kornberg, A, Klug
openaire   +2 more sources

Nucleosome Structure

Annual Review of Biochemistry, 1980
J D, McGhee, G, Felsenfeld
openaire   +2 more sources

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