Results 231 to 240 of about 49,625 (309)

Chromosome segregation in a minimal bacterial cell driven by SMC protein complexes

Protein Science, Volume 35, Issue 6, June 2026.
Abstract Minimal bacterial cells such as JCVI‐Syn3A provide a powerful system for uncovering the essential mechanisms of chromosome organization and segregation. Lacking canonical systems such as Min and ParABS, JCVI‐Syn3A relies primarily on structural maintenance of chromosomes (SMC) protein complexes for partitioning.
Andrew K. Maytin, Benjamin R. Gilbert, Zaida Luthey‐Schulten   +2 more
wiley   +1 more source

A modular framework for automated segmentation and analysis of AFM imaging of chromatin organization. [PDF]

Nucleic Acids Res
Sørensen EW, Pangeni S, Merino Urteaga R, Murray PJ, Rudnizky S, Liao TW, Rashid F, Hwang J, Yamadi M, Feng XA, Zähringer J, Gu S, Davidson IF, Caccianini L, Osorio-Valeriano M, Farnung L, Vos SM, Peters JM, Berger J, Wu C, Hatzakis NS, Kirkegaard JB, Ha T.   +22 more
europepmc   +1 more source

Pitfalls and missing links in current understanding of 4D genomes

Quantitative Biology, Volume 14, Issue 2, June 2026.
Abstract The spatial and temporal organization of the genome—collectively termed the 4D genome—is pivotal for regulating gene expression, maintaining genome stability, and guiding development. The convergence of chromosome conformation capture technologies, super‐resolution microscopy, and single‐cell epigenomics has transformed our understanding of ...
Michael Q. Zhang
wiley   +1 more source

A Self-Organized Liquid Reaction Container for Cellular Memory. [PDF]

Adv Sci (Weinh)
Mukherjee S, Skoruppa E, Merlitz H, Sommer JU, Schiessel H.   +4 more
europepmc   +1 more source

Phenotypic and genetic resistance to Septoria blotch disease in European wheat varieties

The Plant Genome, Volume 19, Issue 2, June 2026.
Abstract Zymoseptoria tritici, the causal agent of Septoria tritici blotch (STB), poses a critical threat to wheat (Triticum aestivum L.) production in temperate Europe, underscoring the need for durable genetic resistance. Here, we screened 151 winter wheat varieties at the seedling stage using a mixed inoculum of five virulent isolates.
Conor Copeland, Julio Isidro y Sánchez, Humberto Fanelli, Fiona M. Doohan   +3 more
wiley   +1 more source

Differential nucleosome organization in human interphase and metaphase chromosomes. [PDF]

Mol Syst Biol
Li K, Unlu I, Tu Y, Voong LN, Lu Y, Kendall B, Ma X, Pui SL, Tao M, Wang JP, Wang X.   +10 more
europepmc   +1 more source

Application of deep learning in crop research: From genomics to phenomics

The Plant Genome, Volume 19, Issue 2, June 2026.
Abstract Deep learning, as a pivotal branch of machine learning, has demonstrated remarkable potential in advancing crop science by effectively integrating genomics and phenomics. This review systematically outlines the application of diverse deep learning architectures—such as convolutional neural networks, recurrent neural networks, and transformers ...
Zefeng Wu, Yali Sun, Qian Luo, Jiaping Wei, Junmei Cui, Yan Fang, Yining Niu, Zhaohong Li, Xiaolin Wang, Zigang Liu   +9 more
wiley   +1 more source

Phosphorylation of Xenopus M18BP1 governs centromeric localization and CENP-A nucleosome assembly. [PDF]

EMBO Rep
Brown RR, Schwartz JP, Ghadri L, Straight AF.   +3 more
europepmc   +1 more source

Loss of SMARCAD1 Mitigates Tauopathy

Aging Cell, Volume 25, Issue 6, June 2026.
Using genetics approaches in a C. elegans transgenic model of tauopathy, we uncover a role for the homolog of human SMARCAD1, a regulator of chromatin dynamics. ABSTRACT Tauopathies are neurodegenerative diseases characterized by the accumulation of misfolded tau protein and include Alzheimer's disease (AD) and related dementia disorders.
Vaishnavi S. Jadhav, Rebecca L. Kow, Asia D. Beale, Misa Baum, Pamela J. McMillan, Caitlin S. Latimer, Nicole F. Liachko, Brian C. Kraemer   +7 more
wiley   +1 more source

Parasite nucleosomes: Chromatin dynamics rewired. [PDF]

PLoS Pathog
Deák G, Wilson MD.
europepmc   +1 more source