Results 241 to 250 of about 74,179 (293)
Genome-wide identification of nucleosome positioning determinants in schizosaccharomyces pombe
Julia Pointner
openalex +2 more sources
Centromere-Specific Assembly of CENP-A Nucleosomes Is Mediated by HJURP
D. Foltz +7 more
semanticscholar +1 more source
We report on the clinical characteristics of three new patients with pathogenic TRRAP variants expanding the syndrome's phenotype. In order to investigate the TRRAP potential involvement in skeletal development, osteoclastogenesis in Patient 1 was evaluated and TRRAP expression in osteoclasts and osteoblasts were analyzed.
Chiara Minotti +17 more
wiley +1 more source
Nucleosome context regulates chromatin reader preference. [PDF]
Marunde MR +45 more
europepmc +1 more source
Chromatin folding by the Polycomb group proteins and its elusive role in epigenetic repression
Genes repressed by the Polycomb system display greater chromatin folding compared to ‘regular’ inactive genes. The associated chromatin compaction, driven by PRC1‐H3K27me3 interactions, is modest and dynamic. This questions traditional models where Polycomb proteins repress transcription by sheltering genes from transcriptional activators.
Ludvig Lizana, Yuri B. Schwartz
wiley +1 more source
Defining transcription factor nucleosome binding with Pioneer-seq. [PDF]
Tsompana M +4 more
europepmc +1 more source
P. acnes infection impairs the mitochondrial biogenesis of nucleus pulposus cells (NPCs) through the AMPK/SIRT‐1/PGC‐1α signaling pathway. This results in impaired mitochondria that are unable to generate sufficient ATP, and impaired delivery of mitochondrial reactive oxygen species to carry out the bactericidal process effectively.
Lemeng Ren +9 more
wiley +1 more source
A molecular census to elucidate the demixing mechanism of membraneless organelles. [PDF]
Ali C, Muzzopappa F, Erdel F.
europepmc +1 more source
Lysine demethylase 4A: from chromatin to centrosomes
The lysine demethylase 4A (KDM4A) remodels chromatin by histone demethylation, regulating gene expression. In this issue, Chowdhury et al. report a previously undescribed localisation for KDM4A outside the nucleus, at the pericentriolar material around the centrosome.
Anushka Sharma +2 more
wiley +1 more source
H2A.Z-nucleosomes are stabilized by the superhelicity-dependent DNA binding of the C-terminal tail of the histone variant. [PDF]
Benhamza I +8 more
europepmc +1 more source

