Results 241 to 250 of about 74,179 (293)

Centromere-Specific Assembly of CENP-A Nucleosomes Is Mediated by HJURP

open access: yesCell, 2009
D. Foltz   +7 more
semanticscholar   +1 more source

Further Exploring the TRRAP Genotype–Phenotype Correlations: Report of Three New Patients With A Focus on Skeletal Anomalies

open access: yesClinical Genetics, Volume 109, Issue 1, Page 181-187, January 2026.
We report on the clinical characteristics of three new patients with pathogenic TRRAP variants expanding the syndrome's phenotype. In order to investigate the TRRAP potential involvement in skeletal development, osteoclastogenesis in Patient 1 was evaluated and TRRAP expression in osteoclasts and osteoblasts were analyzed.
Chiara Minotti   +17 more
wiley   +1 more source

Nucleosome context regulates chromatin reader preference. [PDF]

open access: yesNucleic Acids Res
Marunde MR   +45 more
europepmc   +1 more source

Chromatin folding by the Polycomb group proteins and its elusive role in epigenetic repression

open access: yesThe FEBS Journal, Volume 293, Issue 1, Page 10-25, January 2026.
Genes repressed by the Polycomb system display greater chromatin folding compared to ‘regular’ inactive genes. The associated chromatin compaction, driven by PRC1‐H3K27me3 interactions, is modest and dynamic. This questions traditional models where Polycomb proteins repress transcription by sheltering genes from transcriptional activators.
Ludvig Lizana, Yuri B. Schwartz
wiley   +1 more source

Defining transcription factor nucleosome binding with Pioneer-seq. [PDF]

open access: yesPLoS Genet
Tsompana M   +4 more
europepmc   +1 more source

Propionibacterium acnes evades microbicidal phagocytosis by inhibiting the mitochondrial biogenesis of nucleus pulposus cells

open access: yesThe FEBS Journal, Volume 293, Issue 1, Page 295-317, January 2026.
P. acnes infection impairs the mitochondrial biogenesis of nucleus pulposus cells (NPCs) through the AMPK/SIRT‐1/PGC‐1α signaling pathway. This results in impaired mitochondria that are unable to generate sufficient ATP, and impaired delivery of mitochondrial reactive oxygen species to carry out the bactericidal process effectively.
Lemeng Ren   +9 more
wiley   +1 more source

Lysine demethylase 4A: from chromatin to centrosomes

open access: yesThe FEBS Journal, Volume 293, Issue 2, Page 392-395, January 2026.
The lysine demethylase 4A (KDM4A) remodels chromatin by histone demethylation, regulating gene expression. In this issue, Chowdhury et al. report a previously undescribed localisation for KDM4A outside the nucleus, at the pericentriolar material around the centrosome.
Anushka Sharma   +2 more
wiley   +1 more source

H2A.Z-nucleosomes are stabilized by the superhelicity-dependent DNA binding of the C-terminal tail of the histone variant. [PDF]

open access: yesNucleus
Benhamza I   +8 more
europepmc   +1 more source

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