Results 241 to 250 of about 72,215 (324)

Toll‐Like Receptors in the Immunotherapy Era: Dual‐Edged Swords of Tumor Immunity and Clinical Translation

open access: yesMedComm, Volume 6, Issue 8, August 2025.
This review discussed the signaling pathways of Toll‐like receptors in tumors and their antitumor or protumor regulatory effects in diverse tumors. We also paid attention to the application of Toll‐like receptors in clinical treatment and summarized the clinical trial situation in recent years.
Nueraili Maihemuti   +7 more
wiley   +1 more source

High-throughput epigenetic profiling immunoassays for accelerated disease research and clinical development. [PDF]

open access: yesJ Biol Chem
Van den Ackerveken P   +10 more
europepmc   +1 more source

Pathogenic variants in chromatin‐related genes: Linking immune dysregulation to neuroregression and acute neuropsychiatric disorders

open access: yesDevelopmental Medicine &Child Neurology, Volume 67, Issue 8, Page 1095-1102, August 2025.
Chromatin machinery influences how DNA is ‘wrapped’ around histones in the nucleosome of immune and brain cells. Plain language summary: https://onlinelibrary.wiley.com/doi/10.1111/dmcn.16299 This original article is commented by Thompson on pages 975–976 of this issue. Abstract We report eight children with de novo pathogenic DNA variants in chromatin‐
Russell C. Dale   +14 more
wiley   +1 more source

Exploring the untapped potential of single‐cell and spatial omics in plant biology

open access: yesNew Phytologist, Volume 247, Issue 3, Page 1098-1116, August 2025.
Summary Advances in single‐cell and spatial omics technologies have revolutionised biology by revealing the diverse molecular states of individual cells and their spatial organization within tissues. The field of plant biology has widely adopted single‐cell transcriptome and chromatin accessibility profiling and spatial transcriptomics, which extend ...
Tatsuya Nobori
wiley   +1 more source

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