Results 11 to 20 of about 1,102,607 (331)
Nucleotide excision repair [PDF]
Deep insight on Nucleotide excision ...
LHF Mullenders, A Stary, A Sarasin
core +4 more sources
Nucleotide Excision Repair [PDF]
European Bioinformatics Institute, New York University Langone Medical Center, Ontario Institute for Cancer Research, Oregon Health and Science University.
W. Mcgregor
semanticscholar +3 more sources
Nucleotide excision repair in humans [PDF]
The demonstration of DNA damage excision and repair replication by Setlow, Howard-Flanders, Hanawalt and their colleagues in the early 1960s, constituted the discovery of the ubiquitous pathway of nucleotide excision repair (NER). The serial steps in NER
Graciela Spivak
semanticscholar +3 more sources
Nucleotide Excision Repair in the Third Kingdom [PDF]
ABSTRACT Nucleotide excision repair, a general repair mechanism for removing DNA damage, is initiated by dual incisions bracketing the lesion. In procaryotes, the dual incisions result in excision of the damage in 12- to 13-nucleotide-long oligomers, and in eucaryotes they result in excision of the damage in the form of 24- to 32-
M, Ogrünç +3 more
openaire +4 more sources
Prokaryotic Nucleotide Excision Repair [PDF]
Nucleotide excision repair (NER) has allowed bacteria to flourish in many different niches around the globe that inflict harsh environmental damage to their genetic material.
C. Kisker, J. Kuper, B. Van Houten
semanticscholar +3 more sources
Zuo1 supports G4 structure formation and directs repair toward nucleotide excision repair [PDF]
G4 structure-interacting proteins have been linked to DNA repair processes. Here the authors reveal that in yeast, Zuo1 associates with G4 structures and plays a role in repair pathway choice by promoting nucleotide excision repair and ultimately ...
Alessio De Magis +6 more
doaj +2 more sources
Nucleotide excision repair in eukaryotes. [PDF]
Nucleotide excision repair (NER) is the main pathway used by mammals to remove bulky DNA lesions such as those formed by UV light, environmental mutagens, and some cancer chemotherapeutic adducts from DNA. Deficiencies in NER are associated with the extremely skin cancer-prone inherited disorder xeroderma pigmentosum. Although the core NER reaction and
O. Schärer
semanticscholar +4 more sources
Resistance to Nucleotide Excision Repair of Bulky Guanine Adducts Opposite Abasic Sites in DNA Duplexes and Relationships between Structure and Function. [PDF]
The nucleotide excision repair of certain bulky DNA lesions is abrogated in some specific non-canonical DNA base sequence contexts, while the removal of the same lesions by the nucleotide excision repair mechanism is efficient in duplexes in which all ...
Zhi Liu +6 more
doaj +1 more source
Transcription-coupled Nucleotide Excision Repair: New Insights Revealed by Genomic Approaches
Elongation of RNA polymerase II (Pol II) is affected by many factors including DNA damage. Bulky damage, such as lesions caused by ultraviolet (UV) radiation, arrests Pol II and inhibits gene transcription, and may lead to genome instability and cell ...
Mingrui Duan +4 more
semanticscholar +1 more source
Nucleotide excision repair genes shaping embryonic development [PDF]
Nucleotide excision repair (NER) is a highly conserved mechanism to remove helix-distorting DNA lesions. A major substrate for NER is DNA damage caused by environmental genotoxins, most notably ultraviolet radiation.
Sofia J. Araújo, Isao Kuraoka
doaj +1 more source

