Results 241 to 250 of about 621,729 (284)
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Cyclic Nucleotide Metabolism in Tumours
Australian and New Zealand Journal of Medicine, 1979Summary: Many hormones act by combining with cell surface receptors and stimulating adenylate cyclase activity. The cyclic AMP generated is the mediator of a number of cellular metabolic processes. Other processes may be influenced by changes in cyclic GMP levels.
N H, Hunt, T J, Martin
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Nitrogen metabolism: nucleotide metabolism
2018This chapter talks about nucleotides. These are synthesized de novo. Purine nucleotides are synthesized by a salvage pathway via ribotidation of free bases released by the degradation of nucleotides. The chapter reviews the de novo synthesis of purine nucleotides, wherein the purine ring that is assembled by a series of steps in which the intermediates
Despo Papachristodoulou +3 more
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NUCLEOTIDE METABOLISM IN RAT BRAIN
Journal of Neurochemistry, 1968Abstract— The uptake, the conversion to nucleotides, and their incorporation into RNA for labelled glycine, aspartate, the free bases and nucleosides of purines and pyrimidines were investigated with cortical slices of rat cerebrum. At the end of a 1‐hr incubation time the slice‐to‐medium ratio of the radioactivities for labelled aspartate, glycine ...
J N, Santos +3 more
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SIRTifying intestinal nucleotide metabolism
Trends in Endocrinology & MetabolismThe intestine is a proliferative tissue subjected to a variety of stresses that disturb its homeostasis. A recent study by Tucker et al. demonstrated that loss of the tumor suppressor SIRT4 leads to increased cell proliferation via the de novo nucleotide biosynthesis pathway over the salvage pathway after ionizing irradiation (IR).
Shweta Tiwary +2 more
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1986
A supply of ribonucleoside and deoxyribonucleoside 5′-triphosphates is required for the biosynthesis of nucleic acids (chapters 6 and 8). The synthesis of these compounds occurs in two main stages: (1) the formation of the purine and pyrimidine ring systems and their conversion into the parent ribonucleoside monophosphate, inosine 5′-monophosphate (IMP)
Roger L. P. Adams +2 more
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A supply of ribonucleoside and deoxyribonucleoside 5′-triphosphates is required for the biosynthesis of nucleic acids (chapters 6 and 8). The synthesis of these compounds occurs in two main stages: (1) the formation of the purine and pyrimidine ring systems and their conversion into the parent ribonucleoside monophosphate, inosine 5′-monophosphate (IMP)
Roger L. P. Adams +2 more
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Nucleotide Metabolism and Cell-Cell Interactions
2006Interactions between the vascular endothelium and polymorphonuclear leukocytes (PMNs) are central to PMN emigration into inflamed tissues, and to neutrophil-endothelial crosstalk pathways that modulate inflammatory responses and vascular barrier function.
Holger K, Eltzschig +3 more
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1983
This chapter deals with the enzymes that synthesize and degrade cyclic nucleotides in the central nervous system. The actions of the cyclic nucleotides themselves were reviewed in Volume 1 of this series.
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This chapter deals with the enzymes that synthesize and degrade cyclic nucleotides in the central nervous system. The actions of the cyclic nucleotides themselves were reviewed in Volume 1 of this series.
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