Results 1 to 10 of about 1,426,835 (273)

Metal Ions Sensing by Biodots Prepared from DNA, RNA, and Nucleotides

open access: yesBiosensors, 2021
Nucleic acids that exhibit a high affinity toward noble and transition metal ions have attracted growing attention in the fields of metal ion sensing, toxic metal ion removal, and the construction of functional metal nanostructures.
Maofei Wang   +3 more
doaj   +1 more source

Synthesis of Mixed Dinucleotides by Mechanochemistry

open access: yesMolecules, 2022
We report the synthesis of vitamin B1, B2, and B3 derived nucleotides and dinucleotides generated either through mechanochemical or solution phase chemistry.
Faisal Hayat   +3 more
doaj   +1 more source

Dietary Supplementation with Nucleotides, Short-Chain Fructooligosaccharides, Xylooligosaccharides, Beta-Carotene and Vitamin E Influences Immune Function in Kittens

open access: yesAnimals, 2023
Nucleotides, short-chain fructooligosaccharides (scFOS), xylooligosaccharides (XOS), β-carotene and vitamin E are reported to enhance immune function; however, the evidence of this in cats is limited.
Jujhar Atwal   +7 more
doaj   +1 more source

CoCl2-Mimicked Endothelial Cell Hypoxia Induces Nucleotide Depletion and Functional Impairment That Is Reversed by Nucleotide Precursors

open access: yesBiomedicines, 2022
Chronic hypoxia drives vascular dysfunction by various mechanisms, including changes in mitochondrial respiration. Although endothelial cells (ECs) rely predominantly on glycolysis, hypoxia is known to alter oxidative phosphorylation, promote oxidative ...
Barbara Kutryb-Zajac   +6 more
doaj   +1 more source

Dietary Supplementation of a Mixture of Nucleotides, β-Glucan and Vitamins C and E Improved the Growth and Health Performance of Olive Flounder, Paralichthys olivaceus

open access: yesFishes, 2023
A twelve-week feeding trial was conducted to investigate the effect of dietary supplementation of a functional immunostimulant mixture (FIM; nucleotides, β-glucan and vitamins C and E) on growth, feed utilization, innate immunity, digestive enzyme ...
Nalin Medagoda   +3 more
doaj   +1 more source

Fluorescent Nanoparticles Synthesized from DNA, RNA, and Nucleotides

open access: yesNanomaterials, 2021
Ubiquitous on Earth, DNA and other nucleic acids are being increasingly considered as promising biomass resources. Due to their unique chemical structure, which is different from that of more common carbohydrate biomass polymers, materials based on ...
Maofei Wang   +3 more
doaj   +1 more source

Barcoded Nucleotides [PDF]

open access: yesAngewandte Chemie International Edition, 2011
DNA as an information storage system is simple and at the same time complex owing to the various different arrangements of the four natural nucleotides.[1] The DNA synthesis by DNA polymerases is intriguing, since these enzymes are able to catalyze the elongation of the primer strand by recognizing the DNA template and selecting the corresponding ...
Baccaro, Anna   +2 more
openaire   +3 more sources

Respiratory Cilia as a Therapeutic Target of Phosphodiesterase Inhibitors

open access: yesFrontiers in Pharmacology, 2020
Mucociliary clearance is an essential airway defense mechanism dependent predominantly on the proper ciliary function and mucus rheology. The crucial role of cilia is evident in `a variety of respiratory diseases, as the ciliary dysfunction is associated
Marta Joskova, Juraj Mokry, Sona Franova
doaj   +1 more source

Synthesis and Antiviral Activity of a Series of 2′-C-Methyl-4′-thionucleoside Monophosphate Prodrugs

open access: yesMolecules, 2020
The NS5B RNA-dependent RNA polymerase of the hepatitis C virus (HCV) is a validated target for nucleoside antiviral drug therapy. We endeavored to synthesize and test a series of 4′-thionucleosides with a monophosphate prodrug moiety for their antiviral ...
Zackery W. Dentmon   +2 more
doaj   +1 more source

Cytidine Triphosphate Synthase Four From Arabidopsis thaliana Attenuates Drought Stress Effects

open access: yesFrontiers in Plant Science, 2022
Cytidine triphosphate synthase (CTPS) catalyzes the final step in pyrimidine de novo synthesis. In Arabidopsis, this protein family consists of five members (CTPS1–5), and all of them localize to the cytosol.
Moritz Krämer   +5 more
doaj   +1 more source

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