Results 111 to 120 of about 588,819 (292)

A single nucleotide variant on chromosome 9 residing within ADAMTSL1 distinguishes patients with HER2+ breast cancer.

, 2022
Shahan Mamoor
openalex   +2 more sources

A Two-Single-Nucleotide Polymorphism Haplotype in Promoter Region of CYP11B2 Gene Affects Plasma Aldosterone Concentration: A Matched Case-Control Study [PDF]

, 2020
Fatemeh Nabizadeh, Shabnaz Koochakkhani, Hossein Farshidi, Zahra Farbood, fatemeh kharaee, Tasnim Eghbal Eftekhaari, Elaheh Farahbakhsh, Mahmood Khayatian, Azim Nejatizadeh   +8 more
openalex   +1 more source

Selective and Precise Editing of Digital Polymers Through Parallel or Series Toehold‐Mediated Strand Displacement

Advanced Functional Materials, EarlyView.
A sequence‐encoded supramolecular construct containing two accessible toeholds is developed herein for enabling multiple editing operations. By introducing specific input strands, it is possible to selectively erase or rewrite digital content through parallel or series toehold‐mediated strand displacement (PTMSD or STMSD).
Jakub Ossowski, Cyril Antheaume, Jean‐François Lutz, Maria Nerantzaki   +3 more
wiley   +1 more source

Expanding Chemical Space of Nucleic Acid Nanoparticles for Tunable Antiviral‐Like Immunomodulatory Responses and Potent Adjuvant Activity

Advanced Functional Materials, EarlyView.
We introduce a nucleic acid nanoparticle (NANP) platform designed to be rrecognized by the human innate immune system in a regulated manner. By changing chemical composition while maintaining constant architectural parameters, we identify key determinants of immunorecognition enabling the rational design of NANPs with tunable immune activation profiles
Martin Panigaj, Hannah S. Newton, Jian Wang, Laxmi Pandey, Yelixza I. Avilla, Phong Nguyen, Morgan Chandler, Justin Halman, Yasmine Radwan, Stephanie Smith, Elijah Edmondson, Simone Difilippantonio, Chelsea Sanders, Bao Tran, Yongmei Zhao, Shaojun Xie, Edward Cedrone, Barry W. Neun, Meni Wanunu, Nikolay V. Dokholyan, Marina A. Dobrovolskaia, Kirill A. Afonin   +21 more
wiley   +1 more source

Combinations of diagnostic nucleotides for each of the 20 <i>Chlorella</i>-like taxa recovered in Fig 2.

, 2016
Zou Shanmei, Fei Cong, Song Jiameng, Bao Yachao, He Meilin, Changhai Wang   +5 more
openalex   +2 more sources

Programmable DNA‐Peptide Hybrid Nanostructures for Potent Neutralization of Multiple Influenza a Virus Subtypes

Advanced Functional Materials, EarlyView.
A multivalent antiviral platform based on honeycomb‐shaped DNA nanostructures (HC–Urumin) is developed to enhance the potency and breadth of the host defense peptide Urumin. Through spatially patterned trimeric presentation, HC–Urumin disrupts influenza A virus entry, improves cell viability, and reduces disease severity in vivo‐offering a modular and ...
Saurabh Umrao, Abhisek Dwivedy, Payton L. Haak, Dhanush Gandavadi, Laurie A. Rund, Chi Chen, Vineetha Mareddy, Lifeng Zhou, Jinwei Duan, Ying Fang, Andrew J. Steelman, Xing Wang   +11 more
wiley   +1 more source

New nucleotide sequence data on the EMBL File Server [PDF]

, 1992
P Purdue, M Lumb, M Fox, G Griffo, C Hamon-Benais, S Povey, C Danpure, N Soldatov, N Soldatov, S Izumo, K Philipson, K Wenninger, I Komuro, B Saitta, R Timpl, M Chu, Unpublished, M M81836 H. ; Tenchini, L Marchetti, E Bossi, M Malcovati, R Lorenzetti, M Romkes, M Faletto, J Blaisdell, J Raucy, J Goldstein, M Romkes, M Faletto, J Blaisdell, J Raucy, J Goldstein, M Romkes, M Faletto, J Blaisdell, J Raucy, J Goldstein, M Romkes, M Faletto, J Blaisdell, J Raucy, J Goldstein, M Romkes, M Faletto, J Blaisdell, J Raucy, J Goldstein, P Nhamburo, S Kimura, O Mcbride, C Kozak, H Gelboin, F Gonzalez, D Kwiatkowski, J Unpublished ; Gilman, J Fleckner, H Rasmussen, J Justesen, E Meacci, M Taira, M Moos, C Smith, M Movsesian, E Degerman, P Belfrage, V Manganiello, J Renauld, F Houssiau, A Goethals, E Van Roost, J Van Snick, H, G, H Schooltink, T Stoyan, D Lenz, H Schmitz, T Hirano, T Kishimoto, P Heinrich, S Rose-John, G Adolf, B Fruehbeis, R Hauptmann, I Kalsner, I Maurer-Fogy, E Ostermann, E Patzelt, R Schwendenwein, W Sommergruber, A Zoephel, V Pascual, K Victor, D Lelsz, M Spellerberg, T Hamblin, K Thompson, I Randen, J Natvig, D Capra   +99 more
openalex   +1 more source

Bimetallic Nanoreactor Activates cGAS‐STING Pathway via mtDNA Release for Cancer Metalloimmunotherapy

Advanced Functional Materials, EarlyView.
A bimetallic Mn–Ca nanoreactor (MCC) is developed as a non‐nucleotide STING nanoagonist for cancer metalloimmunotherapy. MCC induces Ca2+ overload and hydroxyl radical generation, resulting in mitochondrial damage and mtDNA release. The released mtDNA cooperates with Mn2+ to robustly activate cGAS–STING signaling.
Xin Wang Mo, Nguyen Thi Nguyen, LiLi Guo, Ngoc Man Phan, Hyunsu Shin, Tae‐il Kim, Yu Seok Youn, Jaeyun Kim   +7 more
wiley   +1 more source

DNA‐Templated 2D Heterostructures as Phototriggered Dynamic Nanohybrids: From Releasing Molecular Loads to Controlling Enzyme Biocatalytic Function

Advanced Functional Materials, EarlyView.
DNA strands are employed both as dynamic linkers and nanoscale templates for the integration of Ag2S nanoparticles on MoS2, which in turn imparted photothermal responsiveness; this feature permits the selective cargo (fluorophore, quantum dots or an enzyme) release from the MoS2 surface in response to local heat induced by light irradiation.
Kai Chen, Haosen Miao, Weiying Hong, Matteo Palma   +3 more
wiley   +1 more source

Synthetic Nanobiology Actuated Lipometabolic Cell Factory for Autologous Tumor Immunotherapy

Advanced Functional Materials, EarlyView.
FA plays a crucial role in the interaction between tumor cells and the tumor microenvironment, especially for the immune response. A biocatalytic immunoenhancement strategy is developed to boost antitumor immunity by FA metabolic orientation to ceramide. Through the design of this delicate catalytic immunoenhancement strategy, the synthetic nanobiology
Shoujie Zhao, Yejing Zhu, Hengchao Yu, Jun Zhu, Bo Wang, Yu Qiao, Zhimin Tian, Junlong Zhao, Lei Liu   +8 more
wiley   +1 more source