Results 201 to 210 of about 749,080 (252)
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Nature, 1976
It is show that in aqueous solution the backbone conformation of adenosine is as much flexible as that of 3'-AMP, 5'-AMP and 3', 5'-ADP indicating that nucleotides are not any more rigid than nucleosides. The flexible conformation of the monomeric components is conserved in the nucleotidyl units of destacked ApA, ApApA and poly(A), but it is not ...
F E, Evans, R H, Sarma
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It is show that in aqueous solution the backbone conformation of adenosine is as much flexible as that of 3'-AMP, 5'-AMP and 3', 5'-ADP indicating that nucleotides are not any more rigid than nucleosides. The flexible conformation of the monomeric components is conserved in the nucleotidyl units of destacked ApA, ApApA and poly(A), but it is not ...
F E, Evans, R H, Sarma
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Phytochemistry, 2004
The natural occurrence of cyclic nucleotides in higher plants, formerly a topic of fierce debate, is now established, as is the presence of nucleotidyl cyclases and cyclic nucleotide phosphodiesterases capable of their synthesis and breakdown. Here we describe the significant properties of cyclic nucleotides, also outlining their second messenger ...
Russell P, Newton, Christopher J, Smith
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The natural occurrence of cyclic nucleotides in higher plants, formerly a topic of fierce debate, is now established, as is the presence of nucleotidyl cyclases and cyclic nucleotide phosphodiesterases capable of their synthesis and breakdown. Here we describe the significant properties of cyclic nucleotides, also outlining their second messenger ...
Russell P, Newton, Christopher J, Smith
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2011
Publisher Summary This chapter discusses the synthesis and degradation of nucleotides. A nucleotide consists of a purine or pyrimidine base, a pentose, and a phosphate. Nucleotides are synthesized by two types of metabolic pathways: de novo synthesis and salvage pathways.
Chung-Eun Ha, N.V. Bhagavan
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Publisher Summary This chapter discusses the synthesis and degradation of nucleotides. A nucleotide consists of a purine or pyrimidine base, a pentose, and a phosphate. Nucleotides are synthesized by two types of metabolic pathways: de novo synthesis and salvage pathways.
Chung-Eun Ha, N.V. Bhagavan
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The Biosynthesis of Nucleotides
2004The synthesis of PRPP from ATP and ribose-5-phosphate is catalyzed by phosphoribosylpyrophosphate synthetase as follows:
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1986
A supply of ribonucleoside and deoxyribonucleoside 5′-triphosphates is required for the biosynthesis of nucleic acids (chapters 6 and 8). The synthesis of these compounds occurs in two main stages: (1) the formation of the purine and pyrimidine ring systems and their conversion into the parent ribonucleoside monophosphate, inosine 5′-monophosphate (IMP)
Roger L. P. Adams +2 more
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A supply of ribonucleoside and deoxyribonucleoside 5′-triphosphates is required for the biosynthesis of nucleic acids (chapters 6 and 8). The synthesis of these compounds occurs in two main stages: (1) the formation of the purine and pyrimidine ring systems and their conversion into the parent ribonucleoside monophosphate, inosine 5′-monophosphate (IMP)
Roger L. P. Adams +2 more
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The separation of nucleotides by isotachophoresis
Journal of Chromatography A, 1972The mono-, di-, and triphosphates of adenosine, cytidine, guanosine, and uridine were sepd. by isotachophoresis in several different electrolyte systems. At lower pH, the differences in step-height were greater, and complete sepn. of a mixt.
FM Frans Everaerts, JL Jozef Beckers
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Fluorinated Nucleosides, Nucleotides and Sugar Nucleotides
Future Medicinal Chemistry, 2023Jonathan P Dolan +3 more
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Reduction of cytidine nucleotides to deoxycytidine nucleotides by mammalian enzymes
Biochimica et Biophysica Acta, 1962Abstract 1. 1. Conditions for the reduction in vitro of cytidine nucleotides to deoxycytidine nucleotides by an extract of the Novikoff ascites rat tumor are described. ATP was required; TPN, Mg 2+ and Fe 3+ stimulated the reaction. The effects of other metal ions and of a number of organic compounds on the reaction are described. 2.
Robert B. Hurlbert, E. Colleen Moore
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2002
Nucleotide wurden erstmals als Bausteine der Nucleinsauren gefunden. Sie sind in charakteristischer Weise aufgebaut und haben inzwischen einer ganzen Substanzklasse gleichermasen aufgebauter Verbindungen ihren Namen gegeben.
Uli Kazmaier +2 more
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Nucleotide wurden erstmals als Bausteine der Nucleinsauren gefunden. Sie sind in charakteristischer Weise aufgebaut und haben inzwischen einer ganzen Substanzklasse gleichermasen aufgebauter Verbindungen ihren Namen gegeben.
Uli Kazmaier +2 more
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Nucleotides as nucleophiles: Reactions of nucleotides with phosphoimidazolide activated guanosine
Origins of life and evolution of the biosphere, 1992An earlier study of the reaction of phosphoimidazolide activated nucleosides (ImpN) in aqueous phosphate buffers indicated two modes of reaction of the phosphate monoanion and dianion. The first mode is catalysis of the hydrolysis of the P-N bond in ImpN's which leads to imidazole and nucleoside 5'-monophosphate.
Anastassia Kanavarioti +2 more
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