Results 201 to 210 of about 588,819 (292)

Assembly of a pangenome uncovers novel non-reference unique insertion sequences in cattle highlighting their genetic diversity. [PDF]

J Anim Sci Biotechnol
Sorin V, Besnard F, Capitan A, Grohs C, Naji MM, Escouflaire C, Fritz S, Lledo J, Eché C, Iampietro C, Donnadieu C, Milan D, Drouilhet L, Tosser-Klopp G, Boichard D, Klopp C, Sanchez MP, Boussaha M.   +17 more
europepmc   +1 more source

Massively parallel reporter assay for mapping gene-specific regulatory regions at single nucleotide resolution

Alastair J Tulloch, Ryan N. Delgado, Rinaldo Catta-Preta, Constance L. Cepko   +3 more
openalex   +1 more source

Lactylation‐Driven YTHDC1 Alleviates MASLD by Suppressing PTPN22‐Mediated Dephosphorylation of NLRP3

Advanced Science, EarlyView.
In MASLD, YTHDC1 undergoes increased lactylation and ubiquitination, reducing its expression. AARS1 mediates lactylation at lysine 565, while disrupted binding to LDHA further promotes lactylation, suppressing YTHDC1. This downregulation enhances PTPN22 mRNA stability, leading to NLRP3 dephosphorylation and activation, which exacerbates inflammation ...
Feng Zhang, Linghua Zeng, Kunkun Zou, Keying Lin, Fangting Yao, Jinglun Song, Shumeng Zhang, Hanshu Feng, Zhichao Yang, Chunlei Wang, Hongtao Diao, Xue Kong, Tengfei Pan, Joonki Kim, Tianqi Duo, Linqiang Li, Yu Bian   +16 more
wiley   +1 more source

Alpha-synuclein amyloids catalyze the degradation of ATP and other nucleotides. [PDF]

Sci Rep
Castillo-Cáceres C, Nova E, Diaz-Espinoza R.   +2 more
europepmc   +1 more source

DIPHOSPHOPYRIDINE NUCLEOTIDE PYROPHOSPHATASE

Journal of Biological Chemistry, 1948
A, KORNBERG, O, LINDBERG
openaire   +2 more sources

Efavirenz or nevirapine in three-drug combination therapy with two nucleoside or nucleotide-reverse transcriptase inhibitors for initial treatment of HIV infection in antiretroviral-naïve individuals

, 2016
Lawrence Mbuagbaw, Sara Mursleen, James Irlam, Alicen B. Spaulding, George W. Rutherford, Nandi Siegfried   +5 more
openalex   +2 more sources

Calcium Shock Enables Efficient and Programmable Particle Delivery for Genome Editing Applications

Advanced Science, EarlyView.
Classical transfection and transduction are inefficient, particularly with confluent cells and organoids, and lack cell type‐specific programmability. This study presents calcium shock (CaSh), a method that dramatically improves particle delivery into single cells, colonies, and organoids.
Nicole Vo, Lorena de Oñate, Maximillian Frank, Xian Hu, Sophie M. Blackburn, Dana V. Foss, Jasmine Villegas, Kunica Asija, Dirk Hockemeyer, Hongxia Fu, Raymond J. Monnat, Ross C. Wilson, Benjamin S. Freedman   +12 more
wiley   +1 more source

Deletion detection in SARS-CoV-2 genomes from COVID-19 patients: elimination of false positives. [PDF]

Virus Evol
Jiang N, Dewey CN, Yin J.
europepmc   +1 more source

Effect of three common IL-17 single nucleotide polymorphisms on the risk of developing gastric cancer

, 2014
Yawen Gao, Meili Xu, Yan Xu, Dan Li, Shenghua Zhou   +4 more
openalex   +2 more sources

A Mussel‐Inspired Bioadhesive Patch to Selectively Kill Glioblastoma Cells

Advanced Science, EarlyView.
An innovative mussel‐inspired bioadhesive patch has been developed for post‐surgical glioblastoma treatment. The patch, which adheres strongly in biological environments, releases a localized treatment. This treatment, acting via reactive oxygen species, shows specific toxicity to glioblastoma cells.
Jose Bolaños‐Cardet, Sara Pugliese, Jordi Bruna, Daniel Ruiz‐Molina, Salvio Suárez‐García, Victor J. Yuste   +5 more
wiley   +1 more source