Results 21 to 30 of about 1,426,835 (273)

Integrated Multi-Omics Analysis for Inferring Molecular Players in Inclusion Body Myositis

open access: yesAntioxidants, 2023
Inclusion body myositis (IBM) is an acquired inflammatory myopathy affecting proximal and distal muscles that leads to weakness in patients over 50.
Judith Cantó-Santos   +15 more
doaj   +1 more source

High-resolution genome-wide functional dissection of transcriptional regulatory regions and nucleotides in human

open access: yesNature Communications, 2018
Genome-wide epigenomic maps have revealed millions of putative enhancers and promoters, but experimental validation of their function and high-resolution dissection of their driver nucleotides remain limited.
Xinchen Wang   +7 more
semanticscholar   +1 more source

Identification of single nucleotides in MoS2 nanopores. [PDF]

open access: yesNature Nanotechnology, 2015
The size of the sensing region in solid-state nanopores is determined by the size of the pore and the thickness of the pore membrane, so ultrathin membranes such as graphene and single-layer molybdenum disulphide could potentially offer the necessary ...
Jiandong Feng   +6 more
semanticscholar   +1 more source

The Human SLC25A33 and SLC25A36 Genes of Solute Carrier Family 25 Encode Two Mitochondrial Pyrimidine Nucleotide Transporters [PDF]

open access: yes, 2014
The human genome encodes 53 members of the solute carrier family 25 (SLC25), also called the mitochondrial carrier family, many of which have been shown to transport inorganic anions, amino acids, carboxylates, nucleotides, and coenzymes across the inner
Agrimi, G.   +6 more
core   +2 more sources

Oncogenic Integration of Nucleotide Metabolism via Fatty Acid Synthase in Non-Hodgkin Lymphoma

open access: yesFrontiers in Oncology, 2021
Metabolic dysfunctions enabling increased nucleotide biosynthesis are necessary for supporting malignant proliferation. Our investigations indicate that upregulation of fatty acid synthase (FASN) and de novo lipogenesis, commonly observed in many cancers,
Dashnamoorthy Ravi   +27 more
doaj   +1 more source

Protein Mass and Calcium Mass of Broiler Chicken with Added Nucleotides at Different Maintenance Temperatures

open access: yesJurnal Sain Peternakan Indonesia, 2021
This study aims to examine the effect of adding nucleotides in broiler rations on the protein mass and calcium mass of broiler chicken reared at different temperatures.
I. Rahmawati, L .D. Mahfudz, S. Kismiati
doaj   +1 more source

Discovering and Mapping the Modified Nucleotides That Comprise the Epitranscriptome of mRNA.

open access: yesCold Spring Harbor Perspectives in Biology, 2019
SUMMARYAn important mechanism of gene expression regulation is the regulated modification of nucleotides in messenger RNA (mRNA). These modified nucleotides affect mRNA translation, stability, splicing, and other processes.
Bastian Linder, S. Jaffrey
semanticscholar   +1 more source

Dietary Supplementation of Brown Seaweed and/or Nucleotides Improved Shrimp Performance, Health Status and Cold-Tolerant Gene Expression of Juvenile Whiteleg Shrimp during the Winter Season

open access: yesMarine Drugs, 2021
This study was aimed to evaluate the efficiency of Sargassumpolycystum and nucleotides- supplemented diets to improve immune response and cold-tolerance of juvenile Litopenaeus vannamei.
Mohamed Abdel-Rahim   +5 more
doaj   +1 more source

Applications of nucleoside-based molecular probes for the in vivo assessment of tumour biochemistry using positron emission tomography (PET)

open access: yesBrazilian Archives of Biology and Technology, 2007
Positron emission tomography (PET) is a non-invasive nuclear imaging technique. In PET, radiolabelled molecules decay by positron emission. The gamma rays resulting from positron annihilation are detected in coincidence and mapped to produce three ...
Leonard I. Wiebe
doaj   +1 more source

Eukaryotic translational termination efficiency is influenced by the 3′ nucleotides within the ribosomal mRNA channel

open access: yesNucleic Acids Research, 2018
When a stop codon is at the 80S ribosomal A site, there are six nucleotides (+4 to +9) downstream that are inferred to be occupying the mRNA channel. We examined the influence of these downstream nucleotides on translation termination success or failure ...
A. Cridge   +3 more
semanticscholar   +1 more source

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