Results 21 to 30 of about 8,017 (202)
Unlocking Enhanced Efficacy of Aminoglycoside Antibiotics Against Pseudomonas aeruginosa. [PDF]
Microb BiotechnolThis opinion article reviews the use and challenges of aminoglycosides on the Gram‐negative pathogen Pseudomonas aeruginosa and highlights recent discoveries of adjuvants and/or other compounds that potentiate the activity of these antibiotics. ABSTRACT Infectious diseases continue to be a global health burden.
Tawiah PO, Sultana S, Dahl JU.
europepmc +2 more sources
Recognition of TMV RNA by the tRNA nucleotidyltransferase [PDF]
FEBS Letters, 1974 Claude Bénicourt, Anne‐Lise Haenni
openalex +5 more sources
Stimulation and inhibition of deoxyribonucleic acid nucleotidyltransferase by oligodeoxyribonucleotides [PDF]
Biochemical Journal, 1962 HM KEIR
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A Phylogeny of Bacterial RNA Nucleotidyltransferases: Bacillus halodurans Contains Two tRNA Nucleotidyltransferases [PDF]
Journal of Bacteriology, 2005 ABSTRACT We have analyzed the distribution of RNA nucleotidyltransferases from the family that includes poly(A) polymerases (PAP) and tRNA nucleotidyltransferases (TNT) in 43 bacterial species. Genes of several bacterial species encode only one member of the nucleotidyltransferase superfamily (NTSF), and if that protein functions
Patricia Bralley +2 more
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RNA minihelices as model substrates for ATP/CTP:tRNA nucleotidyltransferase [PDF]
Biochemical Journal, 1997 Twenty-one RNA minihelices, resembling the coaxially stacked acceptor- /T-stems and T-loop found along the top of a tRNA's three-dimensional structure, were synthesized and used as substrates for ATP/CTP:tRNA nucleotidyltransferases from Escherichia coli and Saccharomyces cerevisiae.
Zengji LI, Yue Sun, L. David THURLOW
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Mechanism of Mg2+-Accompanied Product Release in Sugar Nucleotidyltransferases. [PDF]
Structure, 2018 The nucleotidyl transfer reaction, catalyzed by sugar nucleotidyltransferases (SNTs), is assisted by two active site Mg2+ ions. While studying this reaction using X-ray crystallography, we captured snapshots of the pyrophosphate (product) as it exits along a pocket.
N. Vithani +6 more
semanticscholar +5 more sources
Molecular biology and evolution, 2022 In tRNA maturation, CCA-addition by tRNA nucleotidyltransferase is a unique and highly accurate reaction. While the mechanism of nucleotide selection and polymerization is well understood, it remains a mystery why bacterial and eukaryotic enzymes exhibit
Martina Hager +7 more
semanticscholar +1 more source
EMBO Molecular Medicine, 2023 Dysfunction of the endoplasmic reticulum (ER) in insulin‐producing beta cells results in cell loss and diabetes mellitus. Here we report on five individuals from three different consanguineous families with infancy‐onset diabetes mellitus and severe ...
Luke A Perera +9 more
doaj +1 more source
Identification of a novel aminoglycoside O-nucleotidyltransferase AadA33 in Providencia vermicola
Frontiers in Microbiology, 2022 A novel chromosome-encoded aminoglycoside O-nucleotidyltransferase AadA33 was identified in Providencia vermicola strain P13. The AadA33 shares the highest amino acid identity of 51.28% with the function characterized AadA31.
Chunlin Feng +20 more
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