Results 41 to 50 of about 1,773 (158)

Manipulation of mitochondrial poly(A) polymerase family proteins in Trypanosoma brucei impacts mRNA termini processing

Frontiers in Parasitology
RNA-specific nucleotidyltransferases (rNTrs) add nontemplated nucleotides to the 3′ end of RNA. Two noncanonical rNTRs that are thought to be poly(A) polymerases (PAPs) have been identified in the mitochondria of trypanosomes – KPAP1 and KPAP2.
Clara M. Smoniewski, Poorya Mirzavand Borujeni, Marshall Hampton, Austin Petersen, Sean P. Faacks, Reza Salavati, Sara L. Zimmer   +6 more
doaj   +1 more source

Enzymes are enriched in bacterial essential genes.

PLoS ONE, 2011
Essential genes, those indispensable for the survival of an organism, play a key role in the emerging field, synthetic biology. Characterization of functions encoded by essential genes not only has important practical implications, such as in identifying
Feng Gao, Randy Ren Zhang
doaj   +1 more source

The inhibition of deoxyribonucleic acid nucleotidyltransferase by stilboestrol derivatives [PDF]

Biochemical Journal, 1968
The inhibition by diethylstilboestrol of DNA nucleotidyltransferase isolated from calf thymus was studied. The inhibition exercised by diethylstilboestrol appears to obey competitive kinetics with respect to DNA primer. The activities of both replicative and terminal enzymes were affected to the same extent. There was no evidence of binding between DNA
A R, Fahmy, K, Griffiths
openaire   +2 more sources

Identification of proteins interacting with lupin and Arabidopsis tRNA nucleotidyltransferases [PDF]

, 2000
ATP (CTP):tRNA nucleotidyltransferase catalyzes the addition of CMP and AMP residues to the 3 ' ends of tRNAs that have an incomplete CCA sequence. In eukaryotic cells, nuclear, mitochondrial and chloroplast genomes all encode tRNAs.
Gu, Jun
core   +1 more source

Amikacin: Uses, Resistance, and Prospects for Inhibition

Molecules, 2017
Aminoglycosides are a group of antibiotics used since the 1940s to primarily treat a broad spectrum of bacterial infections. The primary resistance mechanism against these antibiotics is enzymatic modification by aminoglycoside-modifying enzymes that are
Maria S. Ramirez, Marcelo E. Tolmasky
doaj   +1 more source

Crystal Structure of the Catalytic α Subunit of E. coli Replicative DNA Polymerase III [PDF]

, 2006
SummaryBacterial replicative DNA polymerases such as Polymerase III (Pol III) share no sequence similarity with other polymerases. The crystal structure, determined at 2.3 Å resolution, of a large fragment of Pol III (residues 1–917), reveals a unique ...
Georgescu, Roxana E., Lamers, Meindert H., Lee, Sang-Gyu, Kuriyan, John, O'Donnell, Mike   +4 more
core   +1 more source

The Synthesis and Properties of the Sepharose‐Bound tRNA Nucleotidyltransferase [PDF]

European Journal of Biochemistry, 1971
The synthesis of an insoluble tRNA nucleotidyltransferase by covalent coupling of the enzyme to cyanogen bromide‐activated sepharose is described. The sepharose‐bound enzyme is active in the repair of the pCpCpA sequence of tRNA. Most of its properties are identical to the soluble enzyme although its stability, regarding thermal inactivation and ...
S, Litvak, L, Tarrago-Litvak, D S, Carre, F, Chapeville   +3 more
openaire   +2 more sources

Microbial and host‐derived biomarkers for the diagnosis and management of peri‐implant diseases

Periodontology 2000, EarlyView.
Abstract Objectives To critically evaluate the current evidence on microbial and host‐derived biomarkers for the diagnosis and management of peri‐implant diseases, with emphasis on their biological relevance, potential clinical utility, and current translational limitations.
Su Sheng Quach, Ausra Ramanauskaite, Sašo Ivanovski, Pingping Han, Frank Schwarz, Emilio A. Cafferata   +5 more
wiley   +1 more source

Unusual occurrence of two bona-fide CCA-adding enzymes in Dictyostelium discoideum

, 2020
Dictyostelium discoideum, the model organism for the evolutionary supergroup of Amoebozoa, is a social amoeba that, upon starvation, undergoes transition from a unicellular to a multicellular organism.
Stadler, P., Lieselotte Erber, Christian Hammann, Hoffmann, A., Jörg Fallmann, Sonja Prohaska, Hagedorn, M., Fallmann, J., Prohaska, S., Mario Mörl, Betat, H., Erber, L., Heike Betat, Hammann, C., Anne Hoffmann, Monica Hagedorn, Peter F. Stadler, Mörl, M.   +17 more
core   +1 more source

Detecting Antibiotic Resistance in Strains of Selected Gram‐Negative Bacterial Species Using Raman Spectroscopy

Journal of Raman Spectroscopy, Volume 57, Issue 9, Page 1554-1564, September 2026.
Raman spectroscopy successfully identified antibiotic‐resistant Gram‐negative strains. Resistant strains of four bacterial species were discriminated from sensitive ones with 99.1% accuracy using PLS regression. The method allows for rapid, label‐free detection of antibiotic resistance.
Fernanda Sant Ana de Siqueira e Oliveira, Adriano Moraes da Silva, Marcos Tadeu T. Pacheco, Landulfo Silveira Jr.   +3 more
wiley   +1 more source