Results 51 to 60 of about 1,773 (158)
RNA Tailing by Nucleotidyltransferases in Plants: Mechanisms, Functions, and Biological Significance
RNA tailing, the non-templated addition of nucleotides to RNA 3′ ends, is a conserved post-transcriptional modification that plays a critical role in regulating RNA metabolism.
Xintong Xu +6 more
doaj +1 more source
Proteome Analysis of Corynebacterium diphtheriae–Macrophage Interaction
ABSTRACT Contact of Corynebacterium diphtheriae with macrophages induces adaptations on both bacterial and cellular sides. The study presented here was aiming to shed light on the simultaneous intracellular adaptation of the bacteria and changes in the proteome of the phagocytes in response to the internalization of C. diphtheriae.
Luca Musella +6 more
wiley +1 more source
In animals, the main precursor for glycosaminoglycan and furthermore proteoglycan biosynthesis, like hyaluronic acid, is UDP-glucuronic acid, which is synthesized via the nucleotide sugar oxidation pathway.
Roman Gangl +2 more
doaj +1 more source
Emergence of 4',4"-aminoglycoside nucleotidyltransferase in enterococci [PDF]
Enterococcus faecium BM4102 was resistant to macrolide-lincosamide-streptogramin B-type (MLS) antibiotics; tetracycline-minocycline; and high levels of kanamycin, neomycin, tobramycin, and dibekacin but not gentamicin. This aminoglycoside resistance phenotype is new in enterococci.
C, Carlier, P, Courvalin
openaire +2 more sources
Recent Advances in the Molecular Mechanisms of Bacterial Anti‐Phage Defence Systems
Panoptes as an example for an antiphage system consists of OptS producing a cyclic dinucleotide that prevents activation of OptE, a transmembrane protein. Phage T4 infection introduces the sponge protein Acb2 that adsorbs the cyclic dinucleotide thus activating OptE which disrupts the cell membrane aborting phage infection.
Harald Brüssow
wiley +1 more source
Background Although the necessity of divalent magnesium and manganese for full activity of sugar nucleotidyltransferases and glycosyltransferases is well known, the role of these metal cations in binding the substrates (uridine 5'-triphosphate, glucose-1-
Pohl Nicola L +2 more
doaj +1 more source
An E1-E2 fusion protein primes antiviral immune signaling in bacteria
This study demonstrates that bacteria use a ubiquitin transferase-like enzyme to prime cGAS/DncV-like nucleotidyltransferase activation and use a deubiquitinase-like enzyme to decrease activity.
Hannah E. Ledvina +8 more
semanticscholar +1 more source
Abstract Cyanobacterial harmful algal blooms (cHABs) are worldwide issues. Reduced nitrogen forms (ammonium and urea) have recently been measured in freshwater systems at concentrations not previously recorded. These reduced nitrogen forms have been shown to favor the proliferation of harmful cyanobacteria.
Matthew F. Gladfelter +3 more
wiley +1 more source
Two novel antibiotic resistance genes, tet(44) and ant(6)-Ib, are located within a transferable pathogenicity island in Campylobacter fetus subsp. fetus [PDF]
New tetracycline and streptomycin resistance genes, tet(44) and ant(6)-Ib, were identified in Campylobacter fetus subsp. fetus within a transferable pathogenicity island that is typically unique to Campylobacter fetus subsp. venerealis.
Brodard, Isabelle +2 more
core +2 more sources
Metagenomic investigations have the potential to provide unprecedented insights into microbial ecologies, such as those relating to antimicrobial resistance (AMR).
Pablo Rovira +13 more
doaj +1 more source

