Results 51 to 60 of about 6,924 (153)

Small Extracellular Vesicles in Gestational Diabetes Mellitus: Current Landscape and Emerging Diagnostic Horizons

open access: yesJournal of Extracellular Biology, Volume 5, Issue 3, March 2026.
ABSTRACT Gestational diabetes mellitus (GDM) is a common metabolic disorder of pregnancy associated with significant maternal and neonatal morbidity and mortality. Current diagnostic strategies, particularly the oral glucose tolerance test (OGTT), are limited by late detection, variability in diagnostic criteria, and patient burden, highlighting the ...
Mai Ahmed   +3 more
wiley   +1 more source

The potato cyst nematode Globodera pallida overcomes major potato resistance through selection on standing variation at a single locus

open access: yesNew Phytologist, Volume 249, Issue 6, Page 3039-3059, March 2026.
Summary Globodera pallida poses a major threat to potato production, with management strategies primarily relying on genetic resistance. However, increasing virulence in field populations across Western Europe raises major concerns for G. pallida control.
Arno S. Schaveling   +8 more
wiley   +1 more source

Virulence Regulation and Lifestyle Transitions: The Role of c‐di‐GMP and Two‐Component Systems in Erwinia amylovora and Their Evolutionary Context Within Enterobacterales

open access: yesMolecular Plant Pathology, Volume 27, Issue 2, February 2026.
Erwinia amylovora infects apple blossoms by activating the T3SS, then spreads systemically via amylovoran‐mediated biofilms. Transitions between motile and sessile states are regulated by key two‐component systems and c‐di‐GMP. This review summarises infection biology, virulence factors, regulatory networks and evolutionary insights underlying fire ...
Dhirendra Niroula   +3 more
wiley   +1 more source

Network Pharmacology‐Based Identification of Potential Targets and Mechanisms of Isoginkgetin in Gastric Cancer

open access: yesBioMed Research International, Volume 2026, Issue 1, 2026.
Background Isoginkgetin (ISO) is a natural flavonoid with potential anticancer effects. However, the anticancer mechanisms of ISO in gastric cancer remain insufficiently explored. Methods Network pharmacology, TCGA data analysis, and molecular docking were employed to identify potential ISO targets and their involvement in gastric cancer ...
Linen Li   +4 more
wiley   +1 more source

Clinical Efficacy of Traditional Chinese Medicine Chaihu‐Guizhi‐Ganjiang Decoction Combined With Danggui‐Shaoyao‐San for the Treatment of Oligomenorrhea: A Prospective, Open‐Label Clinical Study

open access: yesInternational Journal of Clinical Practice, Volume 2026, Issue 1, 2026.
Objective To assess the efficacy and safety of Chaihu‐Guizhi‐Ganjiang decoction (CGGJD) combined with Danggui‐Shaoyao‐San (DS) in oligomenorrhea treatment. Methods In this prospective open‐label trial, 35 oligomenorrhea patients (30–40 years) received CGGJD‐DS for 3 months, followed by a 2‐month follow‐up.
Mei Yu   +5 more
wiley   +1 more source

Characterization of Giant Myoviridae With Therapeutic Potential Against Grouper Pathogen, Vibrio alginolyticus

open access: yesInternational Journal of Microbiology, Volume 2026, Issue 1, 2026.
Background Vibrio alginolyticus is a gram‐negative bacterium responsible for mass mortality in cultured groupers, leading to significant economic losses in the aquaculture industry. Although preventive measures such as chemical treatments, antibiotics, and pesticides have been employed, these methods have been reported to be toxic to the environment ...
Mohammad Tamrin Mohamad Lal   +9 more
wiley   +1 more source

Mapping the Threat: A Scoping Review of Acinetobacter baumannii–Associated Hospital Infections and Resistance Mechanisms

open access: yesInternational Journal of Microbiology, Volume 2026, Issue 1, 2026.
Background Acinetobacter baumannii is a major cause of hospital‐associated infections (HAIs) globally, particularly in intensive care units (ICUs). Its remarkable environmental resilience and ability to acquire extensive antimicrobial resistance (AMR) have made it a critical threat to patient safety and a top priority pathogen according to the World ...
Yussif Owusu Aboagye   +3 more
wiley   +1 more source

Integrative Bioinformatics and Machine Learning Identify Novel Diagnostic Biomarkers and Molecular Mechanisms in Sjögren’s Syndrome

open access: yesInternational Journal of Genomics, Volume 2026, Issue 1, 2026.
Background Sjögren’s syndrome (SS) is a chronic autoimmune disorder characterized by significant diagnostic challenges due to nonspecific symptoms and a lack of reliable biomarkers, often resulting in delayed diagnosis and suboptimal patient management.
Hua Xu   +9 more
wiley   +1 more source

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