Results 21 to 30 of about 1,773 (158)

The Battle for Survival: The Role of RNA Non-Canonical Tails in the Virus–Host Interaction

Metabolites, 2023
Terminal nucleotidyltransferases (TENTs) could generate a ‘mixed tail’ or ‘U-rich tail’ consisting of different nucleotides at the 3′ end of RNA by non-templated nucleotide addition to protect or degrade cellular messenger RNA.
Xianghui Wen, Ahsan Irshad, Hua Jin
doaj   +1 more source

Cytidines in tRNAs that are required intact by ATP/CTP:tRNA nucleotidyltransferases fromEscherichia coliandSaccharomyces cerevisiae

Nucleic Acids Research, 1990
D L Thurlow
exaly   +2 more sources

Identification of a novel aminoglycoside O-nucleotidyltransferase AadA33 in Providencia vermicola

Frontiers in Microbiology, 2022
A novel chromosome-encoded aminoglycoside O-nucleotidyltransferase AadA33 was identified in Providencia vermicola strain P13. The AadA33 shares the highest amino acid identity of 51.28% with the function characterized AadA31.
Chunlin Feng, Chunlin Feng, Mengdi Gao, Weiyan Jiang, Weina Shi, Anqi Li, Shuang Liu, Lei Zhang, Xueya Zhang, Qiaoling Li, Hailong Lin, Junwan Lu, Junwan Lu, Kewei Li, Hailin Zhang, Yunliang Hu, Qiyu Bao, Qiyu Bao, Qiyu Bao, Xi Lin, Xi Lin   +20 more
doaj   +1 more source

Analysis of Unusual Eukaryotic tRNA Nucleotidyltransferases and Establishment of a High-Throughput Sequencing Method for Mature tRNAs [PDF]

, 2020
Transfer RNA nucleotidyltransferases (CCA-adding enzymes) are important enzymes, which catalyze the attachment of a CCA triplet to the 3‘ end of tRNAs, an essential requirement for subsequent aminoacylation.
Erber, Lieselotte
core   +1 more source

The arms race between bacteria CBASS and bacteriophages

Frontiers in Immunology, 2023
The Bacterial Cyclic oligonucleotide-Based Anti-phage Signaling System (CBASS) is an innate immune system that induces cell suicide to defend against phage infections.
Lan Wang, Lan Wang, Lan Wang, Leiliang Zhang, Leiliang Zhang, Leiliang Zhang   +5 more
doaj   +1 more source

Promiscuous splicing-derived hairpins are dominant substrates of tailing-mediated defense of miRNA biogenesis in mammals

Cell Reports, 2023
Summary: Canonical microRNA (miRNA) hairpins are processed by the RNase III enzymes Drosha and Dicer into ∼22 nt RNAs loaded into an Argonaute (Ago) effector.
Seungjae Lee, David Jee, Sid Srivastava, Acong Yang, Abhinav Ramidi, Renfu Shang, Diane Bortolamiol-Becet, Sébastien Pfeffer, Shuo Gu, Jiayu Wen, Eric C. Lai   +10 more
doaj   +1 more source

CCA-Addition Gone Wild: Unusual Occurrence and Phylogeny of Four Different tRNA Nucleotidyltransferases in Acanthamoeba castellanii

Molecular biology and evolution, 2020
tRNAs are important players in the protein synthesis machinery, where they act as adapter molecules for translating the mRNA codons into the corresponding amino acid sequence.
L. Erber, H. Betat, Mario Mörl
semanticscholar   +1 more source

Bacteriophage antidefense genes that neutralize TIR and STING immune responses

Cell Reports, 2023
Summary: Programmed cell suicide of infected bacteria, known as abortive infection (Abi), serves as an immune defense strategy to prevent the propagation of bacteriophage viruses.
Peiyin Ho, Yibu Chen, Subarna Biswas, Ethan Canfield, Alireza Abdolvahabi, Douglas E. Feldman   +5 more
doaj   +1 more source

Mechanism of Nucleotidyltransfer Reaction and Role of Mg2+ Ion in Sugar Nucleotidyltransferases.

Biophysical Journal, 2020
Sugar nucleotidyl transferases (SNTs) catalyze nucleotidyltransfer reactions to form sugar-nucleotides and pyrophosphate in the presence of two Mg2+ ions (Mg2+A and Mg2+B).
N. Vithani, B. Prakash, N. N. Nair
semanticscholar   +1 more source

Terminal Uridylyltransferases TUT4/7 Regulate microRNA and mRNA Homeostasis

Cells, 2022
The terminal nucleotidyltransferases TUT4 and TUT7 (TUT4/7) regulate miRNA and mRNA stability by 3′ end uridylation. In humans, TUT4/7 polyuridylates both mRNA and pre-miRNA, leading to degradation by the U-specific exonuclease DIS3L2. We investigate the
Pengcheng Zhang, Mallory I. Frederick, Ilka U. Heinemann   +2 more
doaj   +1 more source