Results 31 to 40 of about 8,017 (202)
The Battle for Survival: The Role of RNA Non-Canonical Tails in the Virus–Host Interaction
Metabolites, 2023 Terminal nucleotidyltransferases (TENTs) could generate a ‘mixed tail’ or ‘U-rich tail’ consisting of different nucleotides at the 3′ end of RNA by non-templated nucleotide addition to protect or degrade cellular messenger RNA.
Xianghui Wen, Ahsan Irshad, Hua Jin
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The arms race between bacteria CBASS and bacteriophages
Frontiers in Immunology, 2023 The Bacterial Cyclic oligonucleotide-Based Anti-phage Signaling System (CBASS) is an innate immune system that induces cell suicide to defend against phage infections.
Lan Wang +5 more
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Molecular biology and evolution, 2020 tRNAs are important players in the protein synthesis machinery, where they act as adapter molecules for translating the mRNA codons into the corresponding amino acid sequence.
L. Erber, H. Betat, M. Mörl
semanticscholar +1 more source
Purification and Characterization of a Mutant tRNA Nucleotidyltransferase [PDF]
European Journal of Biochemistry, 1980 tRNA nucleotidyltransferase has been extensively purified from a mutant strain of Escherichia coli which displays greatly decreased AMP incorporation, but normal CMP incorporation. The defect in AMP incorporation is retained throughout the purification of the mutant protein. The mutant protein behaves identically to the wild‐type protein with regard to
Murray P. Deutscher, Robert G. McGANN
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Terminal Uridylyltransferases TUT4/7 Regulate microRNA and mRNA Homeostasis
Cells, 2022 The terminal nucleotidyltransferases TUT4 and TUT7 (TUT4/7) regulate miRNA and mRNA stability by 3′ end uridylation. In humans, TUT4/7 polyuridylates both mRNA and pre-miRNA, leading to degradation by the U-specific exonuclease DIS3L2. We investigate the
Pengcheng Zhang +2 more
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TYMV RNA As a substrate of the tRNA nucleotidyltransferase [PDF]
FEBS Letters, 1970 It has been recently shown that in the presence of partly purified enzyme preparations from Escherichia coli and ATP. lhe RNA (M.W. = 2 × 106) of Turnip Yellow Mosaic Virus (TYMV) reacts with valine forming an ester bond analogous to that existing in aminoacyltRNA: lhe valine estcrifies the., -terminal adenosine ofTYMV RNA II. 21.
Simon Litvak +2 more
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AGO-bound mature miRNAs are oligouridylated by TUTs and subsequently degraded by DIS3L2
Nature Communications, 2020 3′ end of microRNAs binds to the PAZ domain of Argonaute (AGO) proteins. Here the authors show that terminal nucleotidyltransferases TUT4/7 and exonuclease DIS3L2 induce tailing and decay of 3’ end exposed-microRNAs in AGO PAZ mutant expressing- or ...
Acong Yang +6 more
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Frontiers in Microbiology, 2023 BackgroundPaenibacillus thiaminolyticus, a species of genus Paenibacillus of the family Paenibacillaceae, exists widely in environments and habitats in various plants and worms, and occasionally causes human infections.
Junwan Lu +10 more
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Life, 2019 The early metabolism arising in a Thioester world gave rise to amino acids and their simple peptides. The catalytic activity of these early simple peptides became instrumental in the transition from Thioester World to a Phosphate World.
Hyman Hartman, Temple F. Smith
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The inhibition of deoxyribonucleic acid nucleotidyltransferase by stilboestrol derivatives [PDF]
Biochemical Journal, 1968 The inhibition by diethylstilboestrol of DNA nucleotidyltransferase isolated from calf thymus was studied. The inhibition exercised by diethylstilboestrol appears to obey competitive kinetics with respect to DNA primer. The activities of both replicative and terminal enzymes were affected to the same extent. There was no evidence of binding between DNA
K Griffiths, A R Fahmy
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