Results 51 to 60 of about 8,017 (202)
Bacteriophage antidefense genes that neutralize TIR and STING immune responses
Cell Reports, 2023 Summary: Programmed cell suicide of infected bacteria, known as abortive infection (Abi), serves as an immune defense strategy to prevent the propagation of bacteriophage viruses.
Peiyin Ho +5 more
doaj
Dual targeting of the tRNA nucleotidyltransferase in plants: not just the signal [PDF]
Journal of Experimental Botany, 2007 Enzymes involved in tRNA maturation are essential for cytosolic, mitochondrial, and plastid protein synthesis and are therefore localized to these different compartments of the cell. Interestingly, only one isoform of tRNA nucleotidyltransferase (responsible for adding the 3'-terminal cytidine-cytidine-adenosine to tRNAs) has been identified in plants.
Schmidt von Braun, Serena +5 more
openaire +5 more sources
PLoS ONE, 2014 In animals, the main precursor for glycosaminoglycan and furthermore proteoglycan biosynthesis, like hyaluronic acid, is UDP-glucuronic acid, which is synthesized via the nucleotide sugar oxidation pathway.
Roman Gangl +2 more
doaj +1 more source
Food Safety and Health, EarlyView.This study evaluated the antimicrobial susceptibility profile of Escherichia coli isolated from artisanal colonial cheese from Brazil. Sixty percent of the isolates showed resistance to at least one antimicrobial, no ESBL was found, genes blaTEM and tetB were found simultaneously in four isolates.
Luísa Aimée Schmitt Lobe +14 more
wiley +1 more source
Chemistry Central Journal, 2008 Background Although the necessity of divalent magnesium and manganese for full activity of sugar nucleotidyltransferases and glycosyltransferases is well known, the role of these metal cations in binding the substrates (uridine 5'-triphosphate, glucose-1-
Pohl Nicola L +2 more
doaj +1 more source
Proteome Analysis of Corynebacterium diphtheriae–Macrophage Interaction
PROTEOMICS, EarlyView.ABSTRACT Contact of Corynebacterium diphtheriae with macrophages induces adaptations on both bacterial and cellular sides. The study presented here was aiming to shed light on the simultaneous intracellular adaptation of the bacteria and changes in the proteome of the phagocytes in response to the internalization of C. diphtheriae.
Luca Musella +6 more
wiley +1 more source
Measuring catalytic mechanism similarity – a new approach to study enzyme function and evolution
The FEBS Journal, EarlyView.We introduce a previously undescribed computational method to measure the similarity of enzyme mechanisms, enabling comparison of catalytic steps across hundreds of enzymes. Applying this method to a database of enzyme mechanisms demonstrated its ability to automatically uncover functional and evolutionary relationships, independently of sequence and ...
Antonio J. M. Ribeiro +5 more
wiley +1 more source
Nucleotide specificity of the human terminal nucleotidyltransferase Gld2 (TUT2) [PDF]
RNA, 2016 The nontemplated addition of single or multiple nucleotides to RNA transcripts is an efficient means to control RNA stability and processing. Cytoplasmic RNA adenylation and the less well-known uridylation are post-transcriptional mechanisms regulating RNA maturation, activity, and degradation.
David Hyung Suk Jo +2 more
openaire +3 more sources
Frontiers in Microbiology, 2019 Metagenomic investigations have the potential to provide unprecedented insights into microbial ecologies, such as those relating to antimicrobial resistance (AMR).
Pablo Rovira +13 more
doaj +1 more source
An E1–E2 fusion protein primes antiviral immune signalling in bacteria
Nature, 2023 This study demonstrates that bacteria use a ubiquitin transferase-like enzyme to prime cGAS/DncV-like nucleotidyltransferase activation and use a deubiquitinase-like enzyme to decrease activity.
Hannah E. Ledvina +8 more
semanticscholar +1 more source