Results 151 to 160 of about 566,734 (334)

Differential Behavioral Responses to\ud Cocaethylene of Long-Evans and\ud Sprague-Dawley Rats: Role of Serotonin [PDF]

open access: yes, 1997
Cocaethylene is a neuroactive metabolite derived from the concurrent consumption of cocaine and ethanol. The effects of cocaethylene on locomotor activity, stereotypy, and rearing in Long-Evans and Sprague-Dawley rats were compared.A single cocaine ...
Horowitz, Dr. J.M.   +2 more
core  

Quality of life in older adults is enhanced by piano practice: Results from a randomized controlled trial

open access: yesAnnals of the New York Academy of Sciences, EarlyView.
In this randomized controlled trial, 156 older participants were assigned to either piano practice or music listening groups for 12 months. Quality of life was assessed at 0, 6, 12, 18, and ∼48 months. We showed that practicing piano positively impacted psychological, physical, and environmental quality of life, which was associated with bilateral ...
Florian Worschech   +8 more
wiley   +1 more source

Roles for the Uptake\u3csub\u3e2\u3c/sub\u3e Transporter OCT3 in Regulation of Dopaminergic Neurotransmission and Behavior [PDF]

open access: yes, 2019
Transporter-mediated uptake determines the peak concentration, duration, and physical spread of released monoamines. Most studies of monoamine clearance focus on the presynaptic uptake1 transporters SERT, NET and DAT.
Gasser, Paul J.
core   +1 more source

Beyond problematic social media use and the brain: A public health and policy perspective

open access: yesAnnals of the New York Academy of Sciences, EarlyView.
With the rise in social media use comes concerns of problematic patterns of engagement resembling behavioral addictions. We explore the classification, debate, and underlying neurobiological mechanisms of problematic social media use (PSMU). In addition, public health frameworks to mitigate PSMU through health protection, prevention, surveillance, and ...
Holly Shannon   +7 more
wiley   +1 more source

EFFECTS OF REVERSIBLE INACTIVATION OF BILATERAL ACCUMBENS NUCLEI ON MEMORY STORAGE: ANIMAL STUDY IN RAT MODEL

open access: yesJournal of Research in Medical Sciences, 2002
Introduction. Memory and learning play an important role in human"s life that will become problematic in case disability is weak for any reason. There are many factors that facilitate process of mamory and learning of which accumbens nucleus plays an ...
H.A ALAEI   +5 more
doaj  

Cocaine self-administration augments kappa opioid receptor system-mediated inhibition of dopamine activity in the mesolimbic dopamine system

open access: yesIBRO Neuroscience Reports, 2023
Prior studies examining the effects of cocaine on the dynorphin/kappa opioid receptor (Dyn/KOR) system primarily focus on non-contingent cocaine exposure, but the effects of self-administration, which more closely reflects human drug-taking behaviors ...
Paige M. Estave   +5 more
doaj  

Topical application of the cold‐mimetic l‐menthol decreases wheel running without affecting the beneficial effects of voluntary exercise in mice

open access: yesExperimental Physiology, EarlyView.
Abstract Topical application of l‐menthol, a pharmacological cold‐mimetic and agonist of the cold‐sensing receptor TRPM8 (transient receptor potential cation channel subfamily M member 8), has been shown to stimulate brown adipose tissue (BAT) thermogenesis and reduce weight gain in both obese and lean male mice, without affecting energy intake.
Annalaura Bellucci   +8 more
wiley   +1 more source

Neuroinflammation and microglial expression in brains of social-isolation rearing model of schizophrenia

open access: yesIBRO Neuroscience Reports, 2023
Schizophrenia is a psychiatric disorder with a global prevalence of approximately 0.45%. It is considered a mental illness, with negative symptoms, positive symptoms, and cognitive dysfunction.
Gideon Opeyemi Ayilara   +1 more
doaj  

Early adversity and the comorbidity between metabolic disease and psychopathology

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Hierarchical diagram representing the interplay between the genetic background and early life adversities and its effect on multiple physiological processes that ultimately impact on the risk for the comorbdity between psychopathology and cardiometabolic disorders.
Ameyalli Gómez‐Ilescas   +1 more
wiley   +1 more source

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