Results 31 to 40 of about 525,575 (332)
Lithium treatment impacts nucleus accumbens shape in bipolar disorder
NeuroImage: Clinical, 2020 The effects of lithium treatment duration on deep grey matter structures in bipolar disorder are not well known. In this cross-sectional neuroimaging case-control study, we tested the hypothesis that shape characteristics of deep grey matter structures ...
Daniela Vecchio +7 more
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Evidence and explanation for the involvement of the nucleus accumbens in pain processing
Neural Regeneration Research, 2019 The nucleus accumbens (NAc) is a subcortical brain structure known primarily for its roles in pleasure, reward, and addiction. Despite less focus on the NAc in pain research, it also plays a large role in the mediation of pain and is effective as a ...
Haley Harris, Y. Peng
semanticscholar +1 more source
Reward behavior is regulated by the strength of hippocampus-nucleus accumbens synapses
Nature, 2018 Reward drives motivated behaviours and is essential for survival, and therefore there is strong evolutionary pressure to retain contextual information about rewarding stimuli. This drive may be abnormally strong, such as in addiction, or weak, such as in
T. LeGates +6 more
semanticscholar +1 more source
The value of extended amygdala structures in emotive effects of narcogenic with diverse chemical structure [PDF]
Research Results in Pharmacology, 2019 Introduction: Studies on the mechanisms of the reinforcing action of opioid and non-opioid narcotics confirmed the existence in the brain of a specialized system named the extended amygdala.
Roman O. Roik +2 more
doaj +3 more sources
Biomolecules, 2022 G protein-coupled trace amine-associated receptors (TAAR) recognize different classes of amine compounds, including trace amines or other exogenous and endogenous molecules.
Anastasia N. Vaganova +4 more
doaj +1 more source
NeuroImage: Clinical, 2023 Craving is a core symptom of cocaine use disorder and a major factor for relapse risk. To date, there is no pharmacological therapy to treat this disease or at least to alleviate cocaine craving as a core symptom.
Etna J.E. Engeli +11 more
doaj +1 more source
Nature Communications, 2018 Adolescence is a developmental period in which the mesolimbic dopaminergic “reward” circuitry of the brain, including the nucleus accumbens (NAc), undergoes significant plasticity. Dopamine D1 receptors (D1rs) in the NAc are critical for social behavior,
Ashley M. Kopec +4 more
semanticscholar +1 more source
Nucleus Accumbens Invulnerability to Methamphetamine Neurotoxicity [PDF]
ILAR Journal, 2011 Methamphetamine (Meth) is a neurotoxic drug of abuse that damages neurons and nerve endings throughout the central nervous system. Emerging studies of human Meth addicts using both postmortem analyses of brain tissue and noninvasive imaging studies of intact brains have confirmed that Meth causes persistent structural abnormalities.
Donald M, Kuhn +2 more
openaire +2 more sources
Effect of Electrical Stimulation and Lesion of Nucleus Accumbens on EEG of Intact and Addicted Rats [PDF]
Journal of Kerman University of Medical Sciences, 2008 Introduction: The nucleus accumbens is involved in various functions ranging from motivation and reward to feeding and drug addiction. Some researchers have also suggested that this region has some roles in consciousness. In the present study, the effect
M Hosseini +4 more
doaj
Effort discounting in human nucleus accumbens [PDF]
Cognitive, Affective, & Behavioral Neuroscience, 2009 A great deal of behavioral and economic research suggests that the value attached to a reward stands in inverse relation to the amount of effort required to obtain it, a principle known as effort discounting. In the present article, we present the first direct evidence for a neural analogue of effort discounting.
Matthew M, Botvinick +2 more
openaire +2 more sources