Blunted Cystine–Glutamate Antiporter Function in the Nucleus Accumbens Promotes Cocaine-induced Drug Seeking [PDF]
Repeated cocaine alters glutamate neurotransmission, in part, by reducing cystine–glutamate exchange via system xc−, which maintains glutamate levels and receptor stimulation in the extrasynaptic compartment.
Abdulhameed, Omer+5 more
core +1 more source
Effects of hippocampal damage on reward threshold and response rate during self-stimulation of the ventral tegmental area in the rat [PDF]
The main purpose of this study was to explore the role of the hippocampus in motivated behavior. Rats with bilateral excitotoxic lesions of the hippocampus and controls were trained to lever press for electrical stimulation of the ventral tegmental area.
Altman+52 more
core +1 more source
¿Cómo funciona el nucleus accumbens? [PDF]
O nucleus accumbens é considerado uma interfase neural entre a motivaçao, conduta sexual, resposta ao stress, autoadministraçao de drogas, etc. Desenvolvimento. O nucleus accumbens apresenta dois territórios, o núcleus e a cobertura, cujas conexoes desenham nitidamente as suas vertentes motora e límbica.
openaire +3 more sources
Transducer Materials Mediated Deep Brain Stimulation in Neurological Disorders
This review discusses advanced transducer materials for improving deep brain stimulation (DBS) in neurological disorders. These materials respond to light, ultrasound, or magnetic fields, enabling precise, less invasive neuromodulation. Their stimulus‐responsive properties enhance neural control and adaptive therapy, paving the way for next‐generation ...
Di Zhao+5 more
wiley +1 more source
Quantitative pharmacologic MRI: Mapping the cerebral blood volume response to cocaine in dopamine transporter knockout mice [PDF]
The use of pharmacologic MRI (phMRI) in mouse models of brain disorders allows noninvasive in vivo assessment of drug-modulated local cerebral blood volume changes (ΔCBV) as one correlate of neuronal and neurovascular activities.
Demyanenko, Andrey V.+5 more
core +2 more sources
Nucleus Accumbens Invulnerability to Methamphetamine Neurotoxicity [PDF]
Methamphetamine (Meth) is a neurotoxic drug of abuse that damages neurons and nerve endings throughout the central nervous system. Emerging studies of human Meth addicts using both postmortem analyses of brain tissue and noninvasive imaging studies of intact brains have confirmed that Meth causes persistent structural abnormalities.
Donald M. Kuhn+2 more
openaire +3 more sources
Convergence drawing is used to create flexible, microscale, multifunctional fiber‐based neural probes. Optimized materials selection enables individual devices to perform neural recording, electrical stimulation, optogenetics, fiber photometry, fluid delivery, and voltammetric neurotransmitter detection in rodents.
Nicolette Driscoll+16 more
wiley +1 more source
A wireless‐charging sustained oxygen release from conductive microgels (SOCO) served as an antenna and an on‐demand O2 release for nerve regeneration is developed. Introducing “electromagnetic messenger”, using external alternating magnetic field (AMF) to enhance catalytic oxygen release and electrical stimulation to promote the reconstruction of blood
Hoi Man Iao+15 more
wiley +1 more source
Distribution and characterisation of Glucagon-like peptide-1 receptor expressing cells in the mouse brain. [PDF]
© 2015 The Authors.Objective: Although Glucagon-like peptide 1 is a key regulator of energy metabolism and food intake, the precise location of GLP-1 receptors and the physiological relevance of certain populations is debatable.
Cork, SC+5 more
core +2 more sources
Dialectical Thinking Is Linked With Smaller Left Nucleus Accumbens and Right Amygdala
Our current work examined the interface between thinking style and emotional experience at both the behavioral and neuropsychological levels. Thirty-nine Chinese participants completed the triad task, and we calculated the rate of individually selected ...
Hui-Xian Li, Hui-Xian Li, Xiaomeng Hu
doaj +1 more source