Results 71 to 80 of about 525,575 (332)

Effects of age and sex on photoperiod modulation of nucleus accumbens monoamine content and release in adolescence and adulthood

Neurobiology of Sleep and Circadian Rhythms
Day length, or photoperiod, is a reliable environmental cue encoded by the brain's circadian clock that indicates changing seasons and induces seasonal biological processes.
Alexis N. Jameson, Justin K. Siemann, Carrie A. Grueter, BradA. Grueter, Douglas G. McMahon   +4 more
doaj   +1 more source

Adeno-associated virus (AAV)-mediated suppression of Ca2+/calmodulin kinase IV activity in the nucleus accumbens modulates emotional behaviour in mice

BMC Neuroscience, 2007
Background Calcium/calmodulin-dependent protein kinase IV (CaMKIV) controls activity-dependent gene transcription by regulating the activity of the cyclic AMP response element binding protein (CREB). This signaling pathway is involved in gating emotional
Bading Hilmar, Zhang Sheng-Jia, Spanagel Rainer, Schneider Miriam, Klugmann Matthias   +4 more
doaj   +1 more source

Anatomical Progression of Neuropathology in FTLD‐TDP Type C and Linkage to Annexin A11

Annals of Neurology, EarlyView.
Objective Frontotemporal lobar degenerations (FTLD)‐TDP type C (TDP‐C) is distinguished from other FTLD‐TDP subtypes by 3 unique features: (1) invariable onset in the anterior temporal lobe (ATL), (2) phosphorylated TDP‐43 (pTDP) neurites in cortex, and (3) colocalization of all pTDP deposits with annexin A11 (ANXA11).
Allegra Kawles, Caroline Nelson, Ivan Ayala, Elena Barbieri, Rudolph Castellani, Changiz Geula, Tamar Gefen, M. Marsel Mesulam   +7 more
wiley   +1 more source

VTA glutamatergic inputs to nucleus accumbens drive aversion by acting on GABAergic interneurons

Nature Neuroscience, 2016
The ventral tegmental area (VTA) is best known for its dopamine neurons, some of which project to nucleus accumbens (nAcc). However, the VTA also has glutamatergic neurons that project to nAcc.
J. Qi, Shiliang Zhang, Huiling Wang, David J. Barker, Jorge Miranda-Barrientos, M. Morales   +5 more
semanticscholar   +1 more source

Distinct thalamic functional connectivity and volume patterns across focal epilepsies in children: A multimodal neuroimaging study

Epilepsia, EarlyView.
Abstract Objective The thalamus is a key hub in seizure propagation, and its nuclei are emerging targets for neuromodulation. However, the contributions of individual nuclei to epileptic networks remain unclear, particularly in children, who are less studied than adults.
Xiyu Feng, Aswin Chari, Maria H. Eriksson, Freya Prentice, Xiaosong He, Hua Xie, Leigh Sepeta, M. Zubair Tahir, Jonathan D. Clayden, Martin M. Tisdall, Torsten Baldeweg, Rory J. Piper   +11 more
wiley   +1 more source

Nucleus accumbens deep brain stimulation in adult patients suffering from severe and enduring anorexia nervosa (STIMARS): protocol for a pilot study

Frontiers in Psychiatry
BackgroundAffecting adolescent and young adults, anorexia nervosa (AN) has the highest death rate of all mental disorders. Effective treatment options are lacking and a significant proportion of patients develop severe and chronic forms of the disease ...
Philibert Duriez, Philibert Duriez, Giorgia Antonia Simboli, Giorgia Antonia Simboli, Philippe Domenech, Philippe Domenech, Philippe Domenech, Anne Buot, Anne Buot, Casey Halpern, Casey Halpern, Marie Fadigas, Yann Mongin, Aurore Guy-Rubin, Romain Carron, Romain Carron, Catherine Oppenheim, Catherine Oppenheim, Philip Gorwood, Philip Gorwood, Johan Pallud, Johan Pallud, Marc Zanello, Marc Zanello   +23 more
doaj   +1 more source

Is Deep Brain Stimulation a viable treatment for substance-related addiction? [PDF]

Romanian Journal of Neurology, 2019
For the ability to modulate the activity of dysregulated networks Deep Brain Stimulation (DBS) of areas involved in reward system and motivational states may have a potential application in addiction despite risks associated with its invasiveness.
Giusy Guzzi, Angelo Lavano, Serena Marianna Lavano, Rosa Marotta   +3 more
doaj   +1 more source

Activation of D2 dopamine receptor-expressing neurons in the nucleus accumbens increases motivation

Nature Communications, 2016
Striatal dopamine receptor D1-expressing neurons have been classically associated with positive reinforcement and reward, whereas D2 neurons are associated with negative reinforcement and aversion. Here we demonstrate that the pattern of activation of D1
C. Soares-Cunha, B. Coimbra, A. David-Pereira, S. Borges, L. Pinto, Patrício Costa, N. Sousa, A. Rodrigues   +7 more
semanticscholar   +1 more source

Neuroanatomical and functional correlates in borderline personality disorder: A narrative review

Ibrain, Volume 11, Issue 1, Page 19-31, Spring 2025.
Borderline personality disorder (BPD) is considered a dysfunctional, stable, and pervasive alteration in personality functioning with the inability to adapt to the environment, mental rigidity, and ego‐syntonic, and like all personality disorders is a consistent pattern of inner experience and behavior that deviates markedly from the expectations of ...
Giulio Perrotta
wiley   +1 more source

The bivalent side of the nucleus accumbens [PDF]

NeuroImage, 2009
An increasing body of evidence suggests that the nucleus accumbens (NAcc) is engaged in both incentive reward processes and in adaptive responses to conditioned and unconditioned aversive stimuli. Yet, it has been argued that NAcc activation to aversive stimuli may be a consequence of the rewarding effects of their termination, i.e., relief. To address
Levita, L, Hare, Todd A, Voss, H U, Glover, G, Ballon, D J, Casey, B J   +5 more
openaire   +3 more sources