Results 131 to 140 of about 473,018 (289)

Hydrogel Microspheres as Versatile Platforms for Biomedical Research: Design, Properties, and Applications

MedComm, Volume 6, Issue 10, October 2025.
Schematic diagram illustrating the comprehensive landscape of hydrogel microspheres (HMs). (A) The components of HMs. (B) Preparation technologies employed in fabricating HMs. (C) The diverse applications of HMs across different fields. (D) The therapeutic applications of HMs in the treatment of various systemic diseases, demonstrating their potential ...
Meng Yang, Yuanyuan Shi, Feng Wang, Xin Zhang, Jiayi Shao, Fan Yang, Hao Sun, Chong Zhang, Zheng Zhou, Jianyong Huang, Pengyu Lv, Patrick Shu‐Hang Yung, Jin Cheng, Hong‐Jie Huang, Jian‐Quan Wang   +14 more
wiley   +1 more source

Macrophage Efferocytosis as a Therapeutic Strategy in Intervertebral Disc Degeneration

Cell Proliferation, Volume 58, Issue 10, October 2025.
Macrophages, integral to degenerated intervertebral discs, play a critical role in disc degeneration. By performing efferocytosis, they clear apoptotic cells. This article explores the process of efferocytosis, its molecular mechanisms, potential therapeutic implications for intervertebral disc degeneration and future strategies for targeted treatments.
Shijie Chen, Haijun Zhang, Zhaoheng Wang, Daxue Zhu, Yanhu Li, Yizhi Zhang, Dongxin Wang, Shuwei Chen, Huan Liu, Xuewen Kang   +9 more
wiley   +1 more source

Bioactive glass serves as a substrate for maintenance of phenotype of nucleus pulposus cells of the intervertebral disc [PDF]

, 2000
Jean C. Gan, Paul Ducheyne, Edward J. Vresilovic, Irving M. Shapiro   +3 more
openalex   +1 more source

Targeting Ferroptosis With Ginsenoside Rg3 Alleviates Intervertebral Disc Degeneration

Orthopaedic Surgery, Volume 17, Issue 10, Page 2960-2972, October 2025.
Ginsenosides Rg3 were used to repair the degenerative nucleus pulposus; Furthermore, Rg3 was identified as the bioactive molecule that inhibits the occurrence of ferroptosis through inhibiting PRKAA2 expression in degenerated discs. ABSTRACT Objective Intervertebral disc degeneration (IVDD) has been closely associated with ferroptosis in nucleus ...
Weiran Xu, Fei Geng, Kaihui Zhang, Yinhuan Wang   +3 more
wiley   +1 more source

BIOCHEMICAL AND BIOMECHANICAL SUBSTANTIATION OF REPARATIVE REGENERATION OF INTERVERTEBRAL DISCS IN PATIENTS WITH DEGENERATIVE DISC DISEASES

Східноукраїнський медичний журнал, 2020
Degenerative disc diseases occupy the second place in the overall structure of morbidity with temporary disability. In 40% of patients with spinal osteochondrosis, diseases of the locomotor apparatus and connective tissue cause primary disability.
J. A. Bodnarchuk, M. V. Khyzhnjak, О. О. Potapov, N. G. Chopik   +3 more
doaj  

Nucleus pulposus-induced nerve root injury: effects of diclofenac and ketoprofen [PDF]

, 2001
Michael Cornefjord, Kjell Olmarker, Koji Otani, Björn Rydevik   +3 more
openalex   +1 more source

Sagittal Classification of Calcified Lumbar Disc Herniation and Therapeutic Analysis of Percutaneous Endoscopic Interlaminar Discectomy

Orthopaedic Surgery, Volume 17, Issue 10, Page 2887-2894, October 2025.
Calcified lumbar disc herniation (CLDH) is one specific type of lumbar disc herniation (LDH). CLDH was innovatively divided into four grades in our study. ABSTRACT Background Calcified lumbar disc herniation (CLDH) is one specific type of lumbar disc herniation (LDH).
Kai Zhang, Yingchuang Tang, Hanwen Li, Peng Peng, Xingbang Ruan, Xiangyan Zhen, Bin Meng, Huilin Yang, Junxin Zhang, Haiqing Mao, Kangwu Chen   +10 more
wiley   +1 more source

Characterization of nucleus pulposus‐like tissue formed in vitro [PDF]

, 2001
Yongliang Sun, Mark Hurtig, Robert M. Pilliar, Marc D. Grynpas, Rita A. Kandel   +4 more
openalex   +1 more source

Machine learning and quantitative computed tomography radiomics prediction of postoperative functional recovery in paraplegic dogs

Veterinary Surgery, Volume 54, Issue 7, Page 1305-1315, October 2025.
Abstract Objective To develop a computed tomography (CT)‐radiomics‐based machine‐learning algorithm for prediction of functional recovery in paraplegic dogs with acute intervertebral disc extrusion (IVDE). Study design Multivariable prediction model development.
Daniel Low, Scott Rutherford
wiley   +1 more source

Neferine alleviates intervertebral disc degeneration through KEAP1/NRF2/GPX4 and NF-κB signaling pathways

Shanghai Jiaotong Daxue xuebao. Yixue ban
Objective·To investigate the therapeutic effects of neferine (Nef) on intervertebral disc degeneration (IDD) and the underlying regulatory pathways.Methods·The effects of Nef on the viability and proliferation of nucleus pulposus cells were assessed ...
WAN Hongjin, HU Yibin, WANG Xin, ZHANG Kai, QIN An, MA Peixiang, MA Hui, ZHAO Jie   +7 more
doaj   +1 more source