Results 161 to 170 of about 4,980,963 (235)

UCHL3 drives ferroptosis in nucleus pulposus cells by deubiquitinating HMGB1 to activate NCOA4-mediated ferritinophagy. [PDF]

Autophagy
Hu T, Cui P, Zhao X, Wang W, Ma Y, Hu X, Zhang H, Fan Z, Wang D, Huang Q, Pan F, Huang H, Cui C, Chen X, Rong Y, Lu S.   +15 more
europepmc   +1 more source

Cell-loaded gellan gum-based hydrogels for nucleus pulposus regeneration

, 2013
[Excerpt] Limitations of current treatments for intervertebral disc (IVD) degeneration encourage the development of tissue engineering approaches. Injectable hydrogels loaded with cells can be used as substitute material for the inner part of the IVD,
Tsaryk, R., Kirkpatrick, C. James, Reis, R. L., Silva-Correia, Joana, Oliveira, Joaquim M.   +4 more
core  

GPNMB⁺ macrophages promote osteogenic differentiation of nucleus pulposus cells through PDGF signaling in intervertebral disc degeneration. [PDF]

Cell Rep Med
Jiang J, Kong F, Zheng B, Mei Z, Zhu J, Xu X, Pan W, Wang Z, Sun X, Sun K, Huan L, Shi J, Xu H, Guo Y.   +13 more
europepmc   +1 more source

Editorial Expression of Concern: Integrating bioinformatics and experimental validation to Investigate IRF1 as a novel biomarker for nucleus pulposus cells necroptosis in intervertebral disc degeneration. [PDF]

Sci Rep
Zhou K, Wu S, Wu Z, Ran R, Song W, Dong H, Zhang H.   +6 more
europepmc   +1 more source

Mechanism of acupuncture at “Houxi”（SI3） and “Huantiao”（GB30） in influencing autophagy of nucleus pulposus cells by regulating PI3K/AKT/mTOR signaling pathway in rats with lumbar intervertebral disc degeneration

针刺研究
ObjectiveTo observe the effect of acupuncture at the acupoint pair “Houxi”（SI3） and “Huantiao”（GB30） on the phosphatidylinositol-3 kinase （PI3K）/protein kinase B （AKT）/mammalian target of rapamycin （mTOR） signaling pathway and autophagy of nucleus ...
HU Zhi-xiang, WU Han, LÜ Heng, ZHANG Hao, ZHAI Chun-tao, LI Sheng-yun, WANG Zheng-hao, LÜ Yu-e   +7 more
doaj  

HACE1 alleviates intervertebral disc degeneration by inhibiting ferroptosis in nucleus pulposus cells. [PDF]

Sci Rep
Xia J, Zhang W, Jiang Y, Li T, Dong H, Zhu L, Xia Q, Zhao Y, Yi J, Weng Z, Feng S, Xin Z.   +11 more
europepmc   +1 more source

SENP1 mitigates intervertebral disc degeneration: mechanisms involving suppression of pyroptosis and apoptosis in nucleus pulposus cells. [PDF]

J Orthop Surg Res
Xu Z, Hao K, Zhang T, Yang X, Peng S, Yang G, Zhao J, Zhao Y, Wu D.   +8 more
europepmc   +1 more source

Thrombospondin-4 Regulates Lipopolysaccharide-Induced Apoptosis and Inflammation in Nucleus Pulposus Cells via the Phosphatidylinositol 3-Kinase/Protein Kinase B Pathway. [PDF]

Immun Inflamm Dis
Shu Y, Sun C, Chen S.
europepmc   +1 more source

Harnessing Platelet-derived factors to reactivate Nucleus Pulposus cells in Intervertebral Disc Regeneration. [PDF]

Regen Ther
Nardini M, Muraglia A, Zanirato A, Gentili C, Giannarelli E, Ferrari P, Filaci G, Cancedda R, Formica M, Mastrogiacomo M.   +9 more
europepmc   +1 more source

S-palmitoylation regulates the function of the mitochondria-associated endoplasmic reticulum membrane to alleviate the senescence of nucleus pulposus cells. [PDF]

PLoS One
Liang Q, Zhang J, Yan J, Guo W, Zhao J, Lin L, Li S, Feng D, Liao B.   +8 more
europepmc   +1 more source