Results 141 to 150 of about 4,980,963 (235)

Summary of the characteristics of nucleus pulposus tissues obtained from patients: cumulative population doubling level, initial telomere length, and initial telomerase activity of nucleus pulposus chondrocytes.

, 2015
Summary of the characteristics of nucleus pulposus tissues obtained from patients: cumulative population doubling level, initial telomere length, and initial telomerase activity of nucleus pulposus chondrocytes.
Ki-Won Kim (833560), Seo-Won Jeong (833557), Joon-Pyo Juhn (833559), Sung-Wook Cho (833558), Jun-Seok Lee (181420)   +4 more
core   +1 more source

Injectable ECM-mimetic dynamic hydrogels abolish ferroptosis-induced post-discectomy herniation through delivering nucleus pulposus progenitor cell-derived exosomes

Nature Communications
Discectomy-induced ferroptosis of nucleus pulposus cells (NPCs) contributes to postoperative lumbar disc herniation (LDH) recurrence and intervertebral disc degeneration (IDD).
Wenkai Wang, Zhuo Cheng, Miao Yu, Ke Liu, Hongli Duan, Yang Zhang, Xinle Huang, Menghuan Li, Changqing Li, Yan Hu, Zhong Luo, Minghan Liu   +11 more
doaj   +1 more source

Polyethylene microplastics promote nucleus pulposus cell senescence by inducing oxidative stress via TLR4/NOX2 axis

Ecotoxicology and Environmental Safety
This study aimed to detect and characterize microplastics in intervertebral disc and investigate their effects and molecular mechanism on intervertebral disc degeneration.
Weilin Zhang, Zhencong Li, Zhongwei Wang, Kuize Liu, Shengbang Huang, Jinguo Liang, Zhiwen Dai, Weixiong Guo, Chao Mao, Siyuan Chen, Jinsong Wei   +10 more
doaj   +1 more source

Herniation of Nucleus Pulposus (Labeled)

Herniation of nucleus ...
Royal College of Surgeons of Ireland (RCSI)
core  

Role of tumor necrosis factor-alpha, interleukin-8, and dexamethasone in the focal adhesion kinase expression by human nucleus pulposus cells.

, 2007
STUDY DESIGN: Human nucleus pulposus cells from intervertebral disc specimens were cultured to study the effects of tumor necrosis factor (TNF)-alpha and interleukin (IL)-8 on the focal adhesion kinase (FAK) expression by these cells.
이운규
core   +1 more source

Neural precursor cell expressed developmentally downregulated 4–mediated phosphatase and tensin homolog ubiquitination alleviates senescence and apoptosis of nucleus pulposus cells under interleukin-1 beta conditions

Journal of International Medical Research
Objective Increasing evidence indicates that aging and apoptosis of nucleus pulposus cells are closely associated with the pathogenesis of intervertebral disc degeneration.
Yang Lin, Cheng Li, Xuehui Chang, Ye Wang, Shiying Jia   +4 more
doaj   +1 more source

Biomimetic Hydrogels for In Vitro Modelling of Nucleus Pulposus Degeneration: Effects of Extracellular Matrix Compositional Change on Physicochemical Properties and Cell Phenotype

Journal of Functional Biomaterials
The intervertebral disc, an anatomical compartment interposed between vertebral bodies, plays a key role in spine flexibility and compression loading.
Narjes Rashidi, Nicholas Dowell, Derek Covill, John Shepperd, Matteo Santin   +4 more
doaj   +1 more source

Effect of a low-frequency pulsed electromagnetic field on expression and secretion of IL-1β and TNF-α in nucleus pulposus cells

, 2017
Objective To investigate changes in nucleus pulposus cell expression and secretion of interleukin (IL)-1β and tumour necrosis factor (TNF)-α following stimulation with a low-frequency (LF) pulsed electromagnetic field (PEMF).
Jun Zou, Jiale Qian, Yufeng Chen, Huilin Yang   +3 more
core   +1 more source

Effect of electroacupuncture of “Jiaji”（EX-B2） on autophagy and apoptosis of nucleus pulposus cells in degenerative intervertebral disc rabbits based on PI3K/AKT/mTOR pathway

针刺研究
ObjectiveTo observe the effect of electroacupuncture （EA） of bilateral “Jiaji” （EX-B2） on autophagy， apoptosis and phosphoinositide 3-kinase （PI3K）/protein kinase B （AKT）/mammalian target of rapamycin （mTOR） signaling pathway of nucleus pulposus cells in
WANG Min, ZAHNG Yan-lin, ZOU Jing, HUANG Guo-fu, ZHANG Tuo, DING Xiao-han, XIA Lin-hao   +6 more
doaj   +2 more sources

Investigation of the HIF-PHD System in Nucleus Pulposus Cells of the Intervertebral Disc

, 2016
Low back pain is a taxing condition, both on the individual and on society. Although low back pain has several etiologies, intervertebral disc degeneration is considered a likely cause of a large percentage of cases.
Schoepflin, Zachary
core   +1 more source