Results 181 to 190 of about 12,120 (223)

miR-145-5p combined with miR-140-5p regulates the differentiation of bone marrow mesenchymal stem cells into nucleus pulposus cells and its mechanism in the treatment of intervertebral disc degeneration. [PDF]

J Orthop Surg Res
Chen X, Cao K, Feng H.
europepmc   +1 more source

Author Correction: Dynamics of CD44⁺ bovine nucleus pulposus cells with inflammation. [PDF]

Sci Rep
Ferreira JR, Caldeira J, Sousa M, Barbosa MA, Lamghari M, Almeida-Porada G, Gonçalves RM.   +6 more
europepmc   +1 more source

Pure platelet-rich plasma delays intervertebral disc degeneration by activating SIRT1-mediated autophagy in nucleus pulposus cells. [PDF]

J Orthop Surg Res
Han J, Ding Z, Huang J, Zhang Y, Ding Y.
europepmc   +1 more source

ACE-mediated Glycosylation Stabilizes PSAP To Promote GPR37-dependent Macrophage-Nucleus Pulposus Cells Crosstalk and TGFβ Signaling in Alleviating Intervertebral Disc Degeneration. [PDF]

Adv Sci (Weinh)
Guo Y, Wang F, Wang B, Zhou Y, Wang C, Hu T, Wu D.   +6 more
europepmc   +1 more source

Impact of exposing nucleus pulposus cells to direct current

, 2010
Ferguson, SJ, Ito, K, Welz, PM
core  

miR-340-5p alleviates the damage effect of LPS on nucleus pulposus cells by negatively regulating the expression of SOX4. [PDF]

J Orthop Surg Res
Liu Y, Huang L, Gao Z, Hou Y, Kong F, Hou S, Li Z.   +6 more
europepmc   +1 more source

Autologous nucleus pulposus primes T cells to develop into interleukin‐4‐producing effector cells: An experimental study on the autoimmune properties of nucleus pulposus

Journal of Orthopaedic Research, 2009
An autoimmune response to herniated nucleus pulposus has been proposed to constitute a pathophysiologic mechanism for inducing sciatica based on the fact that nucleus pulposus under normal conditions is excluded from the development of immunological ...
Karin Larsson, Björn Rydevik, Kjell Olmarker   +2 more
exaly   +2 more sources

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ASIC3 roles in mechanosensitive elongation of nucleus pulposus cells

Journal of Biomechanics, 2023
Morphological changes of the nucleus pulposus (NP) cells occur concomitantly as part of the intervertebral disc (IVD) degeneration and excessive mechanical loading has been speculated as a significant key factor for contributing to such morphological changes.
Jormay, Lim, Shao-Shiang, Huang, Mohammad, Nikkhoo, Wei-Ting, Tai, Ya-Cherng, Chu, Andy, Chien, Jaw-Lin, Wang   +6 more
openaire   +2 more sources

Stem cell regeneration of the nucleus pulposus

The Spine Journal, 2004
Low back pain due to disc degeneration is one of the largest health problems faced in this nation when judged by lost work time and direct as well as indirect costs. Many experimental methods are being explored to treat or to reverse the effect of disc degeneration. This article reviews the strategy of a tissue engineering approach to disc regeneration.
Makarand V, Risbud, Irving M, Shapiro, Alexander R, Vaccaro, Todd J, Albert   +3 more
openaire   +2 more sources