Results 191 to 200 of about 4,980,963 (235)

An integrated multi-algorithm analysis to decipher senescence and metabolic characteristics in nucleus pulposus cells during disc degeneration. [PDF]

Geroscience
Liao Z, Li M, Chen Z, Yao Z, Wu Y, Tan Z, Qian J, Yang C, Huang L, Xue L, Wang D.   +10 more
europepmc   +1 more source

Macrophage-derived legumain ameliorates excessive mechanical stress-induced ferroptosis of nucleus pulposus cells and intervertebral disc degeneration via integrin αvβ3-Hippo signaling. [PDF]

Cell Mol Biol Lett
Wang P, Xie Z, Deng L, Zhou Y, Xu Z, Gao J, Sun R, Liu L, Wang Z, Wu X, Ren G, Zhang C, Wang Y.   +12 more
europepmc   +1 more source

Wogonin Ameliorates the Oxidative Stress, Apoptosis, and Extracellular Matrix Degradation of Nucleus Pulposus Cells Mediated by <i>Cutibacterium acnes</i> via the MAPK Signaling Pathway: An In Vivo and In Vitro Study. [PDF]

Int J Mol Sci
Jia J, Bai Y, Zhang M, Lei S, Ma M, Gao K, Kang X.   +6 more
europepmc   +1 more source

miR-191-5p attenuates TNF-α-induced inflammation in nucleus pulposus cells via targeting EGR1. [PDF]

J Orthop Surg Res
Yang Z, Li L, Lin R, Cen M.
europepmc   +1 more source

LncRNA MIR100HG induces degenerative changes in intervertebral disc degeneration nucleus pulposus cells by targeting miR-31-5p. [PDF]

J Orthop Surg Res
Tian J, Li Z, Wang F, Zhang J, Zhao L, Ji Y, Huang Y.   +6 more
europepmc   +1 more source

Some of the next articles are maybe not open access.

Related searches:

ASIC3 roles in mechanosensitive elongation of nucleus pulposus cells

Journal of Biomechanics, 2023
Morphological changes of the nucleus pulposus (NP) cells occur concomitantly as part of the intervertebral disc (IVD) degeneration and excessive mechanical loading has been speculated as a significant key factor for contributing to such morphological changes.
Jormay, Lim, Shao-Shiang, Huang, Mohammad, Nikkhoo, Wei-Ting, Tai, Ya-Cherng, Chu, Andy, Chien, Jaw-Lin, Wang   +6 more
openaire   +2 more sources

Autologous nucleus pulposus primes T cells to develop into interleukin-4-producing effector cells: An experimental study on the autoimmune properties of nucleus pulposus

Journal of Orthopaedic Research, 2009
An autoimmune response to herniated nucleus pulposus has been proposed to constitute a pathophysiologic mechanism for inducing sciatica based on the fact that nucleus pulposus under normal conditions is excluded from the development of immunological ...
Kjell Olmarker, Björn Rydevik, Karin Larsson   +2 more
exaly   +2 more sources

Stem cell regeneration of the nucleus pulposus

The Spine Journal, 2004
Low back pain due to disc degeneration is one of the largest health problems faced in this nation when judged by lost work time and direct as well as indirect costs. Many experimental methods are being explored to treat or to reverse the effect of disc degeneration. This article reviews the strategy of a tissue engineering approach to disc regeneration.
Makarand V, Risbud, Irving M, Shapiro, Alexander R, Vaccaro, Todd J, Albert   +3 more
openaire   +2 more sources

Injectable decellularized nucleus pulposus-based cell delivery system for differentiation of adipose-derived stem cells and nucleus pulposus regeneration

Acta Biomaterialia, 2018
Stem cell-based tissue engineering is a promising treatment for intervertebral disc (IVD) degeneration. A bio-scaffold that can maintain the function of transplanted cells and possesses favorable mechanical properties is needed in tissue engineering. Decellularized nucleus pulposus (dNP) has the potential to be a suitable bio-scaffold because it mimics
Tengfei Zhao, Xiaopeng Zhou, Qixin Chen
exaly   +3 more sources

Rabbit nucleus pulposus cells facilitate differentiation of adipose-derived stem cells into nucleus pulposus-like cells

Indian Journal of Cancer, 2015
To investigate the feasibility of inducing adipose-derived stem cells (ADSCs) to nucleus pulposus cells (NPCs).ADSCs were isolated from rabbit while NPCs were isolated from an allogeneic rabbit. NPCs were co-cultured with the 3rd generation ADSCs in co-cultured system. Only NPCs were cultured in single culturing group.
J, Xu, D L, Qi, X J, Pang, C W, Jing
openaire   +2 more sources