Results 211 to 220 of about 4,980,963 (235)
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Notochordal Cells Interact with Nucleus Pulposus Cells: Regulation of Proteoglycan Synthesis
Experimental Cell Research, 1999The disappearance of notochordal cells is correlated with early degenerative changes in the intervertebral disc. With increased disc degeneration there is a marked decrease in proteoglycan synthesis, resulting in loss of mechanical function. One possible mechanism for the decrease in proteoglycan synthesis is the loss of notochordal cells from the ...
D J, Aguiar, S L, Johnson, T R, Oegema
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Malignant Granular Cell Tumor Mimicking Herniated Nucleus Pulposus
Clinical Orthopaedics and Related Research, 1996Peripheral nerve tumors may arise in any nerve, large or small. Their presence is readily apparent when they are superficial, but when they are located in a deep nerve, symptoms can mimic+ the nerve root pain of herniated nucleus pulposus. This case of malignant granular cell tumor, probably of Schwann cell origin, involved the sciatic and tibial ...
A L, Saperstein +4 more
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Immortalization of Human Nucleus Pulposus Cells by a Recombinant SV40 Adenovirus Vector
Spine, 2004Establishment and characterization of a de novo cell line derived from human nucleus pulposus cells using a recombinant simian virus 40 (SV40) adenovirus vector.To assess the feasibility of human nucleus pulposus cell line procurement and to evaluate the character of the resultant outcome to better understand the nature of human nucleus pulposus cells ...
Daisuke, Sakai +8 more
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Mechanobiology of annulus fibrosus and nucleus pulposus cells in intervertebral discs
Cell and Tissue Research, 2019Low back pain (LBP) is a chronic condition that can affect up to 80% of the global population. It is the number one cause of disability worldwide and has enormous socioeconomic consequences. One of the main causes of this condition is intervertebral disc (IVD) degeneration.
Sara Molladavoodi +2 more
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Ultrastructure of the human intervertebral disc: II. Cells of the nucleus pulposus
The Anatomical Record, 1982AbstractThe cells of the intervertebral disc exist in a unique environment; not only are discs subject to large mechanical loads, they are the largest avascular structures in the body. To describe the ultrastructure and age changes in cells from human nucleus pulposus, we studied these cells in individuals ranging in age from the 26th week of fetal ...
J J, Trout, J A, Buckwalter, K C, Moore
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Active cell proliferation contributes to the enlargement of the nascent nucleus pulposus
Developmental DynamicsAbstractBackgroundThe notochord is an embryonic organ involved in forming and patterning the spinal column. The mechanism by which the notochord transforms from a continuous rod to a segmented structure excluded from the vertebrae and residing solely as the nucleus pulposus within the intervertebral disc is understudied.
Rose G. Long +2 more
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