Results 201 to 210 of about 4,980,963 (235)

Expression of cytokeratin and vimentin in nucleus pulposus cells

Differentiation, 1988
With immunohistochemistry using monoclonal antibodies against intermediate filament proteins, nucleus pulposus cells were found to express cytokeratin(s) simultaneously with vimentin in fetal life and childhood. This finding adds to the series of human tissues showing coexpression of cytokeratins and vimentin.
P, Stosiek, M, Kasper, U, Karsten
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Influence of intradiscal medication on nucleus pulposus cells

The Spine Journal, 2013
Eugene Carragee was the first to prove that provocative discography may contribute to intervertebral disc degeneration. Disc degeneration can be induced either by mechanical trauma caused by the puncturing needle or as a pharmacological effect of the drugs instilled into the disc.The aim of this study was to test the influence of cortisone, lidocaine ...
Claudia, Eder, Astrid, Pinsger, Sabrina, Schildboeck, Erwin, Falkner, Philipp, Becker, Michael, Ogon   +5 more
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Differentiation of Menstrual Blood–Derived Stem Cells Toward Nucleus Pulposus-Like Cells in a Coculture System With Nucleus Pulposus Cells

Spine, 2014
Human stromal stem cells derived from menstrual blood (MenSCs) and nucleus pulposus (NP) cells were cocultured under normal or low oxygen (O2) condition.To assess the differentiation capability of MenSCs toward nucleus pulposus cells under normal or low oxygen condition.Given the proliferative capacity and pluripotentiality of mesenchymal stem cells ...
Xuqi, Hu, Yifei, Zhou, Xuhao, Zheng, Naifeng, Tian, Cong, Xu, Wei, Wu, Fan, Li, Sipin, Zhu, Yijing, Zheng, Enxing, Xue, Yang, Yu, Xiaolei, Zhang, Huazi, Xu   +12 more
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Differentiation of mesenchymal stem cells into nucleus pulposus cells in vitro

Journal of Huazhong University of Science and Technology [Medical Sciences], 2008
To find a new source of seed cells for constructing tissue-engineered intervertebral disc, nucleus pulposus (NP) cells and mesenchymal stem cells (MSCs) were isolated from New Zealand white rabbits. The nucleus pulposus cells population was fluorescence-laelled and co-cultured with MSCs with or without direct contact.
Fenghua, Tao, Feng, Li, Guanghui, Li, Feng, Pan   +3 more
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An injectable vehicle for nucleus pulposus cell-based therapy

Biomaterials, 2011
An injectable hydrogel, acting as a reservoir for cell delivery and mimicking the native environment, offers promise for nucleus pulposus (NP) repair and regeneration. Herein, the potential of a stabilised type II collagen hydrogel using poly(ethylene glycol) ether tetrasuccinimidyl glutarate (4S-StarPEG) cross-linker, enriched with hyaluronic acid (HA)
Estelle C, Collin, Sibylle, Grad, Dimitrios I, Zeugolis, Claire S, Vinatier, Johann R, Clouet, Jérôme J, Guicheux, Pierre, Weiss, Mauro, Alini, Abhay S, Pandit   +8 more
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^{Coculture with Partial Digestion Notochordal Cell-Rich Nucleus Pulposus Tissue Activates Degenerative Human Nucleus Pulposus Cells}

Tissue Engineering Part A, 2017
Recent studies suggested that notochordal cells (NCs) and NC-conditioned medium (NCCM) can stimulate cell viability and matrix production of nucleus pulposus cells (NPCs). However, the potential of notochordal cell-rich nucleus pulposus (NRNP) incorporating the native environment of the intervertebral disc (IVD) has not been evaluated. The objective of
Xue-Dong, Bai, Xiao-Chuan, Li, Jia-Hai, Chen, Zi-Ming, Guo, Li-Sheng, Hou, De-Li, Wang, Qing, He, Di-Ke, Ruan   +7 more
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Differentiation of Human Wharton's Jelly Cells Toward Nucleus Pulposus-Like Cells After Coculture with Nucleus Pulposus Cells In Vitro

Tissue Engineering Part A, 2012
The aim of this study was to evaluate whether human Wharton's jelly cells (WJCs) could be differentiated into nucleus pulposus (NP)-like cells by coculturing with NP cells (NPCs) in vitro. WJCs were isolated from the human umbilical cord, and NPCs were isolated from healthy human intervertebral disc.
Dike, Ruan, Yan, Zhang, Deli, Wang, Chao, Zhang, Jianhong, Wu, Chaofeng, Wang, Zhiyuan, Shi, Hongkui, Xin, Chen, Xu, Haifeng, Li, Qing, He   +10 more
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Potential of co‐culture of nucleus pulposus mesenchymal stem cells and nucleus pulposus cells in hyperosmotic microenvironment for intervertebral disc regeneration

Cell Biology International, 2013
AbstractNucleus pulposus mesenchymal stem cells (NPMSCs) are a potential cell source for intervertebral disc (IVD) regeneration, but little is known about their response to IVD‐like high osmolarity (400 mOsm). This study was to investigate the viability, proliferation and protein biosynthesis of nucleus pulposus cells (NPCs), NPMSCs and co‐cultured ...
Yi-Qing, Tao, Cheng-Zhen, Liang, Hao, Li, Yu-Jie, Zhang, Fang-Cai, Li, Gang, Chen, Qi-Xin, Chen   +6 more
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Differentiation of adipose stem cells by nucleus pulposus cells: Configuration effect

Biochemical and Biophysical Research Communications, 2007
Degenerative disc disease (DDD) is a major cause of chronic low back pain. For mild/intermediate DDD, regeneration by injecting adipose stem cells (ASCs) into the nucleus pulposus (NP) may be considered. The goal of this study is to investigate whether NP cells can direct ASCs towards the NP phenotype.
Lu, Z., Zandieh Doulabi, B., Wuisman, P.I.J.M., Bank, R.A., Helder, M.N.   +4 more
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A novel and efficient method for culturing mouse nucleus pulposus cells

Spine Journal, 2019
As degeneration of the nucleus pulposus (NP) is a major cause of intervertebral disc degeneration, research directed toward nucleus pulposus cells (NPCs) is drawing increased attention. However, caused by the difficulties associated with their harvest and culture, there are few reports describing cultivation methods for mouse NP cells (mNPCs).To ...
Junichi Kushioka, Ryota Chijimatsu, Takahiro Makino   +2 more
exaly   +3 more sources