Results 71 to 80 of about 12,671,316 (204)
Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research
FEBS Letters, EarlyView.What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Neglect impairs explicit processing of the mental number line
Frontiers in Human Neuroscience, 2012 Converging evidence suggests that visuospatial attention plays a pivotal role in numerical processing, especially when the task involves the manipulation of numerical magnitudes.
Marco eZorzi +6 more
doaj +1 more source
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Understanding economical outcomes with the mental number line [PDF]
, 2011 With this study we provide evidence that the cognitive processes involved in addition/subtraction, mapped along the mental number line, seem to mediate our understanding of trading verbs.
Carmelo Vicario
core +1 more source
Frontiers in Psychology, 2020 Whether the human brain processes various types of magnitude, such as numbers and time, through a shared representation or whether there are different representations for each type of magnitude is still debated.
Maria Grazia Di Bono +3 more
doaj +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Complexity of processing to activate magnitude representation for common fractions and precision of their magnitude representations in fraction magnitude comparison [PDF]
, 2021 This study investigated processing/strategy complexity to activate magnitude representation for common fractions (1/4, 1/3, 1/2, 2/3, and 3/4), and the precision of their magnitude representations on the mental number line.
Tanida, Yuki, Okamoto, Masahiko
core +1 more source
Phonemic awareness as a pathway to number transcoding
Frontiers in Psychology, 2014 Although verbal and numerical abilities have a well-established interaction, the impact of phonological processing on numeric abilities remains elusive.
Júlia Beatriz Lopes-Silva +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source