Results 61 to 70 of about 2,030,934 (244)

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

Stochastic Effects on the Dynamics of the Resonant Structure of a Lorentz Force MEMS Magnetometer

open access: yesActuators, 2019
Resonance features of slender mechanical parts of Lorentz force MEMS magnetometers are affected by the (weakly) coupled thermo-electro-magneto-mechanical multi-physics governing their dynamics.
Mehrdad Bagherinia, Stefano Mariani
doaj   +1 more source

Mathematical homogenization of inelastic dissipative materials: a survey and recent progress [PDF]

open access: yes, 2017
In this paper, a review of papers on mathematical homogenization of dissipative composites under small strains and on the interplay between homogenization procedure and dissipation due to mechanical work is presented.
CHEMISKY, Yves   +8 more
core   +1 more source

Versatile vector tools for efficient protein screening across multiple expression systems

open access: yesFEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu   +5 more
wiley   +1 more source

Numerical homogenization for indefinite H(curl)-problems [PDF]

open access: yes, 2017
summary:In this paper, we present a numerical homogenization scheme for indefinite, timeharmonic Maxwell’s equations involving potentially rough (rapidly oscillating) coefficients. The method involves an H(curl)-stable, quasi-local operator, which allows
Verfürth, Barbara
core   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

open access: yesFEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty   +13 more
wiley   +1 more source

The role of machine learning for insight into the material behavior of lattices: A surrogate model based on data from finite element simulation

open access: yesResults in Engineering
In recent years, lattice structures have gained extensive attention due to their unique properties and great potential in various fields. Their effective material properties can be obtained by several means, e.g., numerical homogenization methods, finite
Pana Suttakul   +7 more
doaj   +1 more source

Optimization in multiscale thermoelastic problems [PDF]

open access: yesComputer Methods in Materials Science, 2014
The paper is devoted to the optimization in two-scale thermoelastic problems. The problems are solved by means of evolutionary computation and direct analysis based on a numerical homogenization.
Adam Długosz
doaj   +1 more source

Multiscale homogenization of multilayered structures [PDF]

open access: yes, 2015
In this paper, the analytical solution of the multiple - step homogenization problem for multi - rank composites with generalized periodicity made of elastic materials is presented.
BONNAY, Kevin   +3 more
core  

In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols

open access: yesFEBS Open Bio, EarlyView.
Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton   +6 more
wiley   +1 more source

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